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BindingDB Data by Journal

PMIDDataArticle TitleCitationOrganizationSD Files Download
232753488The naphthoquinone diospyrin is an inhibitor of DNA gyrase with a novel mechanism of action.BDBJ Biol Chem 288: 5149-56 (2013)John Innes Centre2D 3D TSV
2330619539Thiolactomycin-based ▀-Ketoacyl-AcpM Synthase A (KasA) Inhibitors: FRAGMENT-BASED INHIBITOR DISCOVERY USING TRANSIENT ONE-DIMENSIONAL NUCLEAR OVERHAUSER EFFECT NMR SPECTROSCOPY.BDBJ Biol Chem 288: 6045-52 (2013)Institute for Chemical Biology & Drug Discovery2D 3D TSV
235489081Inhibition of isoleucyl-tRNA synthetase as a potential treatment for human African Trypanosomiasis.BDBJ Biol Chem 288: 14256-63 (2013)University of Washington2D 3D TSV
236159038The A128T resistance mutation reveals aberrant protein multimerization as the primary mechanism of action of allosteric HIV-1 integrase inhibitors.BDBJ Biol Chem 288: 15813-20 (2013)The Ohio State University2D 3D TSV
2366169915Structural and biochemical characterization of compounds inhibiting Mycobacterium tuberculosis pantothenate kinase.BDBJ Biol Chem 288: 18260-70 (2013)Uppsala University2D 3D TSV
237750756Functional selectivity of 6'-guanidinonaltrindole (6'-GNTI) at kappa-opioid receptors in striatal neurons.BDBJ Biol Chem 288: 22387-98 (2013)The Scripps Research Institute2D 3D TSV
2379296110Site-specific inhibitory mechanism for amyloid ▀42 aggregation by catechol-type flavonoids targeting the Lys residues.BDBJ Biol Chem 288: 23212-24 (2013)Kyoto University2D 3D TSV
237375233The chlorite dismutase (HemQ) from Staphylococcus aureus has a redox-sensitive heme and is associated with the small colony variant phenotype.BDBJ Biol Chem 288: 23488-504 (2013)University of Notre Dame2D 3D TSV
238399876Laccaic acid A is a direct, DNA-competitive inhibitor of DNA methyltransferase 1.BDBJ Biol Chem 288: 23858-67 (2013)University of Iowa2D 3D TSV
2383994219Heterodimerization with Its splice variant blocks the ghrelin receptor 1a in a non-signaling conformation: a study with a purified heterodimer assembled into lipid discs.BDBJ Biol Chem 288: 24656-65 (2013)UniversitÚ Montpellier 12D 3D TSV
238530923Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages.BDBJ Biol Chem 288: 25362-74 (2013)University of Queensland2D 3D TSV
238281987Key mutations alter the cytochrome P450 BM3 conformational landscape and remove inherent substrate bias.BDBJ Biol Chem 288: 25387-99 (2013)University of Manchester2D 3D TSV
238646603Crystal structure of 3-hydroxybenzoate 6-hydroxylase uncovers lipid-assisted flavoprotein strategy for regioselective aromatic hydroxylation.BDBJ Biol Chem 288: 26235-45 (2013)Wageningen University2D 3D TSV
2388442210Roles of phosphate recognition in inositol 1,3,4,5,6-pentakisphosphate 2-kinase (IPK1) substrate binding and activation.BDBJ Biol Chem 288: 26908-13 (2013)McGill University2D 3D TSV
2389782160Histone deacetylase (HDAC) inhibitor kinetic rate constants correlate with cellular histone acetylation but not transcription and cell viability.BDBJ Biol Chem 288: 26926-43 (2013)Genentech, Inc.2D 3D TSV
239400477Nicotinamide adenine dinucleotide-induced multimerization of the co-repressor CtBP1 relies on a switching tryptophan.BDBJ Biol Chem 288: 27836-48 (2013)Oregon Health and Science University2D 3D TSV
2393509916Discovery of novel irreversible inhibitors of interleukin (IL)-2-inducible tyrosine kinase (Itk) by targeting cysteine 442 in the ATP pocket.BDBJ Biol Chem 288: 28195-206 (2013)GlaxoSmithKline2D 3D TSV
2393510520Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability.BDBJ Biol Chem 288: 28217-29 (2013)National Institutes of Health, National Institutes of Health Biomedical Research Center2D 3D TSV
239553449Pre-existent asymmetry in the human cyclooxygenase-2 sequence homodimer.BDBJ Biol Chem 288: 28641-55 (2013)University of Michigan Medical School2D 3D TSV
239283584VKORC1L1, an enzyme rescuing the vitamin K 2,3-epoxide reductase activity in some extrahepatic tissues during anticoagulation therapy.BDBJ Biol Chem 288: 28733-42 (2013)Institut National de Recherche Agronomique (INRA)-Vetagro Sup, Veterinary School of Lyon2D 3D TSV
239600738FRAX597, a small molecule inhibitor of the p21-activated kinases, inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated Schwannomas.BDBJ Biol Chem 288: 29105-14 (2013)The Scripps Research Institute2D 3D TSV
240032201Evaluation of cancer dependence and druggability of PRP4 kinase using cellular, biochemical, and structural approaches.BDBJ Biol Chem 288: 30125-38 (2013)Sanofi Oncology2D 3D TSV
2400323214Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa.BDBJ Biol Chem 288: 30223-35 (2013)University of Virginia2D 3D TSV
2402248918Structural basis of mycobacterial inhibition by cyclomarin ABDBJ Biol Chem 288: 30883-91 (2013)Novartis Institute for Tropical Diseases2D 3D TSV