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BindingDB Data by Journal




PMIDDataArticle TitleCitationOrganizationSD Files Download
241945205Evidence of ternary complex formation in Trypanosoma cruzi trans-sialidase catalysis.BDBJ Biol Chem 289: 423-36 (2014)Universidade Federal do Rio de Janeiro2D 3D TSV
241871399Defining the communication between agonist and coactivator binding in the retinoid X receptor a ligand binding domain.BDBJ Biol Chem 289: 814-26 (2014)University of Alabama at Birmingham2D 3D TSV
242259507Identification of a small peptide that inhibits PCSK9 protein binding to the low density lipoprotein receptor.BDBJ Biol Chem 289: 942-55 (2014)Genentech, Inc.2D 3D TSV
242577466A L-lysine transporter of high stereoselectivity of the amino acid-polyamine-organocation (APC) superfamily: production, functional characterization, and structure modeling.BDBJ Biol Chem 289: 1377-87 (2014)Max Planck Institute of Biophysics2D 3D TSV
243276569The molecular chaperone Hsp70 activates protein phosphatase 5 (PP5) by binding the tetratricopeptide repeat (TPR) domain.BDBJ Biol Chem 289: 2908-17 (2014)University of Michigan2D 3D TSV
2435697037Structure-guided development of specific pyruvate dehydrogenase kinase inhibitors targeting the ATP-binding pocket.BDBJ Biol Chem 289: 4432-43 (2014)University of Texas Southwestern Medical Center2D 3D TSV
243794015A novel sirtuin 2 (SIRT2) inhibitor with p53-dependent pro-apoptotic activity in non-small cell lung cancer.BDBJ Biol Chem 289: 5208-16 (2014)Universitńt Duisburg-Essen2D 3D TSV
244435694The different inhibition mechanisms of OXA-1 and OXA-24 ▀-lactamases are determined by the stability of active site carboxylated lysine.BDBJ Biol Chem 289: 6152-64 (2014)Case Western Reserve University2D 3D TSV
245234095Coregulator control of androgen receptor action by a novel nuclear receptor-binding motif.BDBJ Biol Chem 289: 8839-51 (2014)Karlsruhe Institute of Technology2D 3D TSV
2449763938Affinity map of bromodomain protein 4 (BRD4) interactions with the histone H4 tail and the small molecule inhibitor JQ1.BDBJ Biol Chem 289: 9304-19 (2014)Bayer HealthCare2D 3D TSV
246342238Trimethylation of histone H3 lysine 36 by human methyltransferase PRDM9 protein.BDBJ Biol Chem 289: 12177-88 (2014)University of Toronto2D 3D TSV
246342192A novel small-molecule tumor necrosis factor a inhibitor attenuates inflammation in a hepatitis mouse model.BDBJ Biol Chem 289: 12457-66 (2014)Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College2D 3D TSV
246442813Fatty acid-binding protein 5 (FABP5) regulates cognitive function both by decreasing anandamide levels and by activating the nuclear receptor peroxisome proliferator-activated receptor ▀/d (PPAR▀/d) in the brain.BDBJ Biol Chem 289: 12748-58 (2014)Case Western Reserve University School of Medicine2D 3D TSV
246957356The Parkinson disease-linked LRRK2 protein mutation I2020T stabilizes an active state conformation leading to increased kinase activity.BDBJ Biol Chem 289: 13042-53 (2014)Harvard NeuroDiscovery Center2D 3D TSV
246485212Deciphering the binding of caveolin-1 to client protein endothelial nitric-oxide synthase (eNOS): scaffolding subdomain identification, interaction modeling, and biological significance.BDBJ Biol Chem 289: 13273-83 (2014)St. Paul's Hospital's Centre of Heart and Lung Innovation2D 3D TSV
246688047Biochemical, cellular, and biophysical characterization of a potent inhibitor of mutant isocitrate dehydrogenase IDH1.BDBJ Biol Chem 289: 13717-25 (2014)National Institutes of Health2D 3D TSV
2473731618Structural basis of pharmacological chaperoning for human ▀-galactosidase.BDBJ Biol Chem 289: 14560-8 (2014)The University of Tokyo2D 3D TSV
2469255118Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor ▀/d (FABP5-PPAR▀/d) signaling pathway.BDBJ Biol Chem 289: 14941-54 (2014)Emory University School of Medicine2D 3D TSV
247532542Functional rescue of Kallmann syndrome-associated prokineticin receptor 2 (PKR2) mutants deficient in trafficking.BDBJ Biol Chem 289: 15518-26 (2014)Central South University; Changsha Medical University2D 3D TSV
2474268014Structural basis for the recognition of peptide RJPXD33 by acyltransferases in lipid A biosynthesis.BDBJ Biol Chem 289: 15527-35 (2014)University of Michigan2D 3D TSV
247426814Oxysterol-binding protein (OSBP)-related protein 4 (ORP4) is essential for cell proliferation and survival.BDBJ Biol Chem 289: 15705-17 (2014)Dalhousie University2D 3D TSV
2473938814Rational design of broad spectrum antibacterial activity based on a clinically relevant enoyl-acyl carrier protein (ACP) reductase inhibitor.BDBJ Biol Chem 289: 15987-6005 (2014)University of Wuerzburg2D 3D TSV
247193293Inhibition of the ribonuclease H activity of HIV-1 reverse transcriptase by GSK5750 correlates with slow enzyme-inhibitor dissociation.BDBJ Biol Chem 289: 16270-7 (2014)McGill University2D 3D TSV
247552266Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration.BDBJ Biol Chem 289: 16349-61 (2014)University of Colorado School of Medicine2D 3D TSV
2478231310In vitro resistance selections for Plasmodium falciparum dihydroorotate dehydrogenase inhibitors give mutants with multiple point mutations in the drug-binding site and altered growth.BDBJ Biol Chem 289: 17980-95 (2014)Harvard School of Public Health2D 3D TSV
247983375Human UTY(KDM6C) is a male-specific N┐-methyl lysyl demethylase.BDBJ Biol Chem 289: 18302-13 (2014)University of Oxford2D 3D TSV
248470826Opioid receptor function is regulated by post-endocytic peptide processing.BDBJ Biol Chem 289: 19613-26 (2014)Icahn School of Medicine at Mount Sinai2D 3D TSV
248915056Two amino acid residues confer different binding affinities of Abelson family kinase SRC homology 2 domains for phosphorylated cortactin.BDBJ Biol Chem 289: 19704-13 (2014)Yale University2D 3D TSV
2483101011ORA1, a zebrafish olfactory receptor ancestral to all mammalian V1R genes, recognizes 4-hydroxyphenylacetic acid, a putative reproductive pheromone.BDBJ Biol Chem 289: 19778-88 (2014)German Institute of Human Nutrition Potsdam-Rehbruecke2D 3D TSV
2486009414Structure of the Acinetobacter baumannii dithiol oxidase DsbA bound to elongation factor EF-Tu reveals a novel protein interaction site.BDBJ Biol Chem 289: 19869-80 (2014)University of Queensland2D 3D TSV
248724112Structure of REV-ERB▀ ligand-binding domain bound to a porphyrin antagonist.BDBJ Biol Chem 289: 20054-66 (2014)The Scripps Research Institute2D 3D TSV
2491766736Digoxin derivatives with enhanced selectivity for the a2 isoform of Na,K-ATPase: effects on intraocular pressure in rabbits.BDBJ Biol Chem 289: 21153-62 (2014)Weizmann Institute of Science2D 3D TSV
2493605926The role of a novel auxiliary pocket in bacterial phenylalanyl-tRNA synthetase druggability.BDBJ Biol Chem 289: 21651-62 (2014)AstraZeneca R&D Boston2D 3D TSV
249625842Chemical proteomics identifies heterogeneous nuclear ribonucleoprotein (hnRNP) A1 as the molecular target of quercetin in its anti-cancer effects in PC-3 cells.BDBJ Biol Chem 289: 22078-89 (2014)National Taiwan University2D 3D TSV