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Compounds Sorted by Binding Data per Compound

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22   23   24   25   26   27   28   29   30   31   32   33   34   35   36   37   38   39   40   41   42   
43   44   45   46   47   48   49   50   51   52   53   54   55   56   57   58   59   60   61   62   63   
64   65   66   67   68   69   70   71   72   73   74   75   76   77   78   79   80   81   82   83   84   
85   86   87   88   89   90   91   92   93   94   95   96   97   99   100   101   102   103   104   105   107   
108   109   110   111   112   113   114   115   116   118   119   121   122   123   124   125   126   127   128   130   131   
133   137   138   139   140   141   142   143   144   146   147   148   150   152   153   154   156   157   158   159   160   
162   163   164   165   168   169   171   172   173   174   177   183   185   186   188   190   196   198   199   203   206   
207   208   213   215   216   219   224   225   227   230   233   237   246   249   261   262   263   277   285   297   299   
303   308   311   317   326   330   333   335   336   337   344   359   360   379   389   391   413   442   443   444   445   
446   447   448   450   453   454   456   460   461   462   464   465   467   469   471   482   496   511   516   517   518   
529   531   539   559   571   583   790   804   818   821   824   831   839   841   848   849   851   853   859   869   876   
880   913   922   923   931   938   966   975   990   1015   1016   1018   1027   1058   1096   1125   1196   1381   1438   1490   1608   
Compounds Sorted Alphabetically
Compound Name
(alphabetical)
Enz. Inhib. DataITC DataBinding TargetsAlternate Compound Names
KiIC50KdEC50KoffKonOther
BDBM1000
PNG
01000000
  • HIV-1 Protease
  • 4-hydroxy-3-[(2-phenoxyethyl)sulfanyl]-2H-chromen-2-one
  • Hydroxycoumarin deriv. 38
  • I-Hydroxy-3-[ (2-phenoxyethy1)thio]-2H-1-benzopyran-2-one
BDBM10000
PNG
01000000
  • Cytochrome P450 19A1
  • (4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)pyridin-3-ylmethanol
  • 6-Methoxybenzofuran-2-yl-(4-fluorophenyl)-3-pyridylmethanol
  • Benzofuran Pyridine Derivative 4a
BDBM100000
PNG
00010000
  • Kallikrein 7
  • 6-chloranyl-8-[(4-methylpiperazin-1-yl)methyl]-7-oxidanyl-4-phenyl-chromen-2-one
  • 6-chloro-7-hydroxy-8-[(4-methyl-1-piperazinyl)methyl]-4-phenyl-1-benzopyran-2-one
  • 6-chloro-7-hydroxy-8-[(4-methylpiperazin-1-yl)methyl]-4-phenylchromen-2-one
  • 6-chloro-7-hydroxy-8-[(4-methylpiperazino)methyl]-4-phenyl-coumarin
  • MLS000036895
  • SMR000042457
  • cid_5389374
BDBM100001
PNG
00010000
  • Kallikrein 7
  • 7-(2-methoxyphenyl)-5-(4-methylphenyl)-1,7-dihydro-[1,2,3,4]tetrazolo[1,5-a]pyrimidine
  • 7-(2-methoxyphenyl)-5-(4-methylphenyl)-1,7-dihydrotetrazolo[1,5-a]pyrimidine
  • 7-(2-methoxyphenyl)-5-(p-tolyl)-1,7-dihydrotetrazolo[1,5-a]pyrimidine
  • MLS000040097
  • SMR000042678
  • cid_5389462
BDBM100002
PNG
00010000
  • Kallikrein 7
  • 3-(4-bromophenyl)-2-methyl-7-oxidanyl-8-(pyrrolidin-1-ylmethyl)chromen-4-one
  • 3-(4-bromophenyl)-7-hydroxy-2-methyl-8-(1-pyrrolidinylmethyl)-1-benzopyran-4-one
  • 3-(4-bromophenyl)-7-hydroxy-2-methyl-8-(pyrrolidin-1-ylmethyl)chromen-4-one
  • 3-(4-bromophenyl)-7-hydroxy-2-methyl-8-(pyrrolidinomethyl)chromone
  • MLS000083057
  • SMR000044899
  • cid_5389772
BDBM100003
PNG
00010000
  • Kallikrein 7
  • 5-ethyl-6-(2-pyridinyl)-6H-benzimidazolo[1,2-c]quinazoline
  • 5-ethyl-6-(2-pyridyl)-6H-benzimidazolo[1,2-c]quinazoline
  • 5-ethyl-6-pyridin-2-yl-6H-benzimidazolo[1,2-c]quinazoline
  • MLS000082913
  • SMR000045193
  • cid_664311
BDBM100004
PNG
00010000
  • Kallikrein 7
  • 3-(4-bromophenyl)-7-hydroxy-8-(4-morpholinylmethyl)-1-benzopyran-4-one
  • 3-(4-bromophenyl)-7-hydroxy-8-(morpholin-4-ylmethyl)chromen-4-one
  • 3-(4-bromophenyl)-7-hydroxy-8-(morpholinomethyl)chromone
  • 3-(4-bromophenyl)-8-(morpholin-4-ylmethyl)-7-oxidanyl-chromen-4-one
  • MLS000083050
  • SMR000045235
  • cid_5389824
BDBM100005
PNG
00010000
  • Kallikrein 7
  • 1-(9-methoxy-5H-pyrimid[5,4-b]indol-4-yl)isonipecotic acid ethyl ester
  • 1-(9-methoxy-5H-pyrimido[5,4-b]indol-4-yl)-4-piperidinecarboxylic acid ethyl ester
  • MLS000040611
  • SMR000045614
  • cid_664591
  • ethyl 1-(9-methoxy-5H-pyrimido[5,4-b]indol-4-yl)piperidine-4-carboxylate
BDBM100006
PNG
00010000
  • Kallikrein 7
  • 1-[bis(2-methoxyethyl)amino]-3-methyl-4-pyrido[1,2-a]benzimidazolecarbonitrile
  • 1-[bis(2-methoxyethyl)amino]-3-methyl-pyrido[1,2-a]benzimidazole-4-carbonitrile
  • 1-[bis(2-methoxyethyl)amino]-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile
  • MLS000084004
  • SMR000046970
  • cid_665778
BDBM100007
PNG
00010000
  • Kallikrein 7
  • 2,8,10-trimethyl-N-(2-morpholin-4-ylethyl)pyrido[2,3]pyrazolo[2,4-a]pyrimidin-4-amine
  • 2,8,10-trimethyl-N-[2-(4-morpholinyl)ethyl]-4-pyrido[2,3]pyrazolo[2,4-a]pyrimidinamine
  • 2-morpholinoethyl-(2,8,10-trimethylpyrido[2,3]pyrazolo[2,4-a]pyrimidin-4-yl)amine
  • MLS000083949
  • SMR000048616
  • cid_667283
BDBM100008
PNG
00010000
  • Kallikrein 7
  • 2-amino-3,5-dichloro-benzoic acid [2-keto-2-[(2-keto-2-methoxy-ethyl)amino]ethyl] ester
  • 2-amino-3,5-dichlorobenzoic acid [2-[(2-methoxy-2-oxoethyl)amino]-2-oxoethyl] ester
  • MLS000058024
  • SMR000063092
  • [2-[(2-methoxy-2-oxidanylidene-ethyl)amino]-2-oxidanylidene-ethyl] 2-azanyl-3,5-bis(chloranyl)benzoate
  • [2-[(2-methoxy-2-oxoethyl)amino]-2-oxoethyl] 2-amino-3,5-dichlorobenzoate
  • cid_2106737
BDBM100009
PNG
00010000
  • Kallikrein 7
  • 3-methyl-1-[2-(2H-1,2,3,4-tetrazol-5-yl)ethyl]-4,6-bis(trifluoromethyl)pyrazolo[3,4-b]pyridine
  • 3-methyl-1-[2-(2H-tetrazol-5-yl)ethyl]-4,6-bis(trifluoromethyl)pyrazolo[3,4-b]pyridine
  • MLS000053578
  • SMR000066416
  • cid_2112393
BDBM10001
PNG
01000000
  • Cytochrome P450 19A1
  • (4-chlorophenyl)(6-methoxy-1-benzofuran-2-yl)pyridin-3-ylmethanol
  • 6-Methoxybenzofuran-2-yl-(4-chlorophenyl)-3-pyridylmethanol
  • Benzofuran Pyridine Derivative 4b
BDBM100010
PNG
00010000
  • Kallikrein 7
  • (2-morpholin-4-yl-2-oxidanylidene-ethyl) 3-methoxynaphthalene-2-carboxylate
  • (2-morpholin-4-yl-2-oxoethyl) 3-methoxynaphthalene-2-carboxylate
  • 3-methoxy-2-naphthalenecarboxylic acid [2-(4-morpholinyl)-2-oxoethyl] ester
  • 3-methoxynaphthalene-2-carboxylic acid (2-keto-2-morpholino-ethyl) ester
  • MLS000054284
  • SMR000066227
  • cid_2347973
BDBM100011
PNG
00010000
  • Kallikrein 7
  • (3-methyl-1-pyridin-2-yl-6-thiophen-2-yl-pyrazolo[3,4-b]pyridin-4-yl)-morpholin-4-yl-methanone
  • (3-methyl-1-pyridin-2-yl-6-thiophen-2-ylpyrazolo[3,4-b]pyridin-4-yl)-morpholin-4-ylmethanone
  • MLS000053976
  • SMR000063405
  • [3-methyl-1-(2-pyridinyl)-6-thiophen-2-yl-4-pyrazolo[3,4-b]pyridinyl]-(4-morpholinyl)methanone
  • [3-methyl-1-(2-pyridyl)-6-(2-thienyl)pyrazolo[3,4-b]pyridin-4-yl]-morpholino-methanone
  • cid_2999639
BDBM100012
PNG
00010000
  • Kallikrein 7
  • 1'-(ethoxycarbonyl)-1-methyl-9-oxo-8,9-dihydrospiro[furo[3,2-f]chromene-7,4'-piperidine]-2-carboxylic acid
  • 1'-carbethoxy-9-keto-1-methyl-spiro[8H-furo[3,2-f]chromene-7,4'-piperidine]-2-carboxylic acid
  • 1'-ethoxycarbonyl-1-methyl-9-oxidanylidene-spiro[8H-furo[3,2-f]chromene-7,4'-piperidine]-2-carboxylic acid
  • 1'-ethoxycarbonyl-1-methyl-9-oxo-2-spiro[8H-furo[3,2-f][1]benzopyran-7,4'-piperidine]carboxylic acid
  • 1'-ethoxycarbonyl-1-methyl-9-oxospiro[8H-furo[3,2-f]chromene-7,4'-piperidine]-2-carboxylic acid
  • MLS000093697
  • SMR000029315
  • cid_3236756
BDBM100013
PNG
00010000
  • Kallikrein 7
  • 6-(4-morpholinyl)-3-[3-(1-piperidinyl)propyl]-2-sulfanylidene-1H-quinazolin-4-one
  • 6-morpholin-4-yl-3-(3-piperidin-1-ylpropyl)-2-sulfanylidene-1H-quinazolin-4-one
  • 6-morpholin-4-yl-3-(3-piperidin-1-ylpropyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one
  • 6-morpholino-3-(3-piperidinopropyl)-2-thioxo-1H-quinazolin-4-one
  • MLS000095423
  • SMR000030977
  • cid_3237415
BDBM100014
PNG
00010000
  • Kallikrein 7
  • 4-(3-cyano-2,7,7-trimethyl-5-oxo-1,4,6,8-tetrahydroquinolin-4-yl)benzoic acid methyl ester
  • 4-(3-cyano-5-keto-2,7,7-trimethyl-1,4,6,8-tetrahydroquinolin-4-yl)benzoic acid methyl ester
  • MLS000084922
  • SMR000019268
  • cid_3239514
  • methyl 4-(3-cyano-2,7,7-trimethyl-5-oxidanylidene-1,4,6,8-tetrahydroquinolin-4-yl)benzoate
  • methyl 4-(3-cyano-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinolin-4-yl)benzoate
  • methyl 4-(3-cyano-2,7,7-trimethyl-5-oxo-1,4,6,8-tetrahydroquinolin-4-yl)benzoate
BDBM100015
PNG
00010000
  • Kallikrein 7
  • (4-methylpiperazino)-(2-p-phenetyl-4-quinolyl)methanone
  • 2-(4-ethoxyphenyl)-4-[(4-methylpiperazin-1-yl)carbonyl]quinoline
  • MLS000254486
  • SMR000031815
  • [2-(4-ethoxyphenyl)-4-quinolinyl]-(4-methyl-1-piperazinyl)methanone
  • [2-(4-ethoxyphenyl)quinolin-4-yl]-(4-methylpiperazin-1-yl)methanone
  • cid_1540951
BDBM100016
PNG
00010000
  • Kallikrein 7
  • 3-[3-keto-4-(2-piperidinoethyl)-[1,2,4]triazino[2,3-a]benzimidazol-2-yl]propionic acid
  • 3-[3-oxidanylidene-4-(2-piperidin-1-ylethyl)-[1,2,4]triazino[2,3-a]benzimidazol-2-yl]propanoic acid
  • 3-[3-oxo-4-(2-piperidin-1-ylethyl)-3,4-dihydro[1,2,4]triazino[2,3-a]benzimidazol-2-yl]propanoic acid
  • 3-[3-oxo-4-(2-piperidin-1-ylethyl)-[1,2,4]triazino[2,3-a]benzimidazol-2-yl]propanoic acid
  • 3-[3-oxo-4-[2-(1-piperidinyl)ethyl]-[1,2,4]triazino[2,3-a]benzimidazol-2-yl]propanoic acid
  • MLS000090309
  • SMR000024919
  • cid_3243524
BDBM100017
PNG
00010000
  • Kallikrein 7
  • 3-O-ethyl 8-O-methyl 4-(furan-2-ylmethylamino)quinoline-3,8-dicarboxylate
  • 3-ethyl 8-methyl 4-[(2-furylmethyl)amino]-3,8-quinolinedicarboxylate
  • 4-(2-furanylmethylamino)quinoline-3,8-dicarboxylic acid O3-ethyl ester O8-methyl ester
  • 4-(2-furfurylamino)quinoline-3,8-dicarboxylic acid O3-ethyl ester O8-methyl ester
  • MLS000063391
  • O3-ethyl O8-methyl 4-(furan-2-ylmethylamino)quinoline-3,8-dicarboxylate
  • SMR000072645
  • cid_1078123
BDBM100018
PNG
00010000
  • Kallikrein 7
  • 1-(3-imidazo[1,2-a]pyrimidin-2-ylphenyl)sulfonylisonipecotic acid ethyl ester
  • 1-[3-(2-imidazo[1,2-a]pyrimidinyl)phenyl]sulfonyl-4-piperidinecarboxylic acid ethyl ester
  • MLS000050929
  • SMR000078644
  • cid_2963573
  • ethyl 1-(3-imidazo[1,2-a]pyrimidin-2-ylphenyl)sulfonylpiperidine-4-carboxylate
  • ethyl 1-[(3-imidazo[1,2-a]pyrimidin-2-ylphenyl)sulfonyl]-4-piperidinecarboxylate
BDBM100019
PNG
00010000
  • Kallikrein 7
  • 4-[[3-cyano-6-methyl-4-(3-pyridinyl)-2-pyridinyl]thio]-3-oxobutanoic acid ethyl ester
  • 4-[[3-cyano-6-methyl-4-(3-pyridyl)-2-pyridyl]thio]-3-keto-butyric acid ethyl ester
  • MLS000050710
  • SMR000078182
  • cid_2216919
  • ethyl 4-(3-cyano-6-methyl-4-pyridin-3-yl-pyridin-2-yl)sulfanyl-3-oxidanylidene-butanoate
  • ethyl 4-(3-cyano-6-methyl-4-pyridin-3-ylpyridin-2-yl)sulfanyl-3-oxobutanoate
  • ethyl 4-[(3'-cyano-6'-methyl-3,4'-bipyridin-2'-yl)thio]-3-oxobutanoate
BDBM100020
PNG
00010000
  • Kallikrein 7
  • 5-(1,3-dimethyl-4-pyrazolyl)-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinecarboxylic acid ethyl ester
  • 5-(1,3-dimethylpyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester
  • MLS000051031
  • SMR000078824
  • cid_1259796
  • ethyl 5-(1,3-dimethyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate
  • ethyl 5-(1,3-dimethylpyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate
BDBM100021
PNG
00010000
  • Kallikrein 7
  • MLS000116805
  • SMR000093764
  • cid_5308363
BDBM100022
PNG
00010000
  • Kallikrein 7
  • MLS000101497
  • SMR000016153
  • cid_4433439
BDBM100023
PNG
00010000
  • Kallikrein 7
  • 7-(2-methoxyphenyl)-5-phenyl-1,7-dihydro-[1,2,3,4]tetrazolo[1,5-a]pyrimidine
  • 7-(2-methoxyphenyl)-5-phenyl-1,7-dihydrotetrazolo[1,5-a]pyrimidine
  • MLS000112062
  • SMR000107979
  • cid_5310598
BDBM100024
PNG
00010000
  • Kallikrein 7
  • MLS000113735
  • N-(2-thiophen-2-yl-3H-benzimidazol-5-yl)acetamide
  • N-(2-thiophen-2-yl-3H-benzimidazol-5-yl)ethanamide
  • N-[2-(2-thienyl)-3H-benzimidazol-5-yl]acetamide
  • SMR000109627
  • cid_892943
BDBM100025
PNG
00010000
  • Kallikrein 7
  • 3-(2-furanylmethyl)-2-phenyl-1,2-dihydroquinazolin-4-one
  • 3-(2-furfuryl)-2-phenyl-1,2-dihydroquinazolin-4-one
  • 3-(furan-2-ylmethyl)-2-phenyl-1,2-dihydroquinazolin-4-one
  • MLS000113614
  • SMR000109510
  • cid_2928530
BDBM100026
PNG
00010000
  • Kallikrein 7
  • 1-(2-oxolanylmethyl)-4-(3-thiophenyl)-4H-pyridine-3,5-dicarboxylic acid dimethyl ester
  • 1-(tetrahydrofurfuryl)-4-(3-thienyl)-4H-pyridine-3,5-dicarboxylic acid dimethyl ester
  • MLS000111356
  • SMR000107280
  • cid_2906112
  • dimethyl 1-(oxolan-2-ylmethyl)-4-thiophen-3-yl-4H-pyridine-3,5-dicarboxylate
BDBM100027
PNG
00010000
  • Kallikrein 7
  • MLS000111994
  • N-[4-(3-cyclohexyl-4-keto-1,2-dihydroquinazolin-2-yl)phenyl]acetamide
  • N-[4-(3-cyclohexyl-4-oxidanylidene-1,2-dihydroquinazolin-2-yl)phenyl]ethanamide
  • N-[4-(3-cyclohexyl-4-oxo-1,2-dihydroquinazolin-2-yl)phenyl]acetamide
  • SMR000107912
  • cid_2920453
BDBM100028
PNG
00010000
  • Kallikrein 7
  • 7-hydroxy-8-(4-morpholinylmethyl)-3-phenyl-1-benzopyran-4-one
  • 7-hydroxy-8-(morpholin-4-ylmethyl)-3-phenylchromen-4-one
  • 7-hydroxy-8-(morpholinomethyl)-3-phenyl-chromone
  • 8-(morpholin-4-ylmethyl)-7-oxidanyl-3-phenyl-chromen-4-one
  • MLS000108260
  • SMR000104221
  • cid_5310763
BDBM100029
PNG
00010000
  • Kallikrein 7
  • 4-(4-imidazo[1,2-a]pyridin-2-ylphenyl)sulfonylmorpholine
  • 4-[4-(2-imidazo[1,2-a]pyridinyl)phenyl]sulfonylmorpholine
  • MLS000111470
  • SMR000107392
  • cid_696014
BDBM10003
PNG
01000000
  • Cytochrome P450 19A1
  • 1-[(6-Methoxybenzofuran-2-yl)-(4-methoxyphenyl)methyl]-1H-imidazole
  • 1-[(6-methoxy-1-benzofuran-2-yl)(4-methoxyphenyl)methyl]-1H-imidazole
  • Benzofuran Imidazole Derivative 6
BDBM100030
PNG
00010000
  • Kallikrein 7
  • 4-(4-carbomethoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester
  • 4-(4-methoxycarbonylphenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester
  • MLS000111732
  • SMR000107654
  • cid_607320
  • dimethyl 4-(4-methoxycarbonylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate
BDBM100031
PNG
00010000
  • Kallikrein 7
  • MLS000527663
  • N-(2,3-dimethyl-6-quinoxalinyl)-1-piperidinecarboxamide
  • N-(2,3-dimethylquinoxalin-6-yl)piperidine-1-carboxamide
  • Piperidine-1-carboxylic acid (2,3-dimethyl-quinoxalin-6-yl)-amide
  • SMR000120237
  • cid_804520
BDBM100032
PNG
00010000
  • Kallikrein 7
  • 2-[4-amino-3-methyl-5-(3-methylphenyl)pyrazolo[3,4-d]pyrimidin-6-yl]sulfanyl-1-pyrrolidin-1-ylethanone
  • 2-[4-azanyl-3-methyl-5-(3-methylphenyl)pyrazolo[3,4-d]pyrimidin-6-yl]sulfanyl-1-pyrrolidin-1-yl-ethanone
  • 2-[[4-amino-3-methyl-5-(3-methylphenyl)-6-pyrazolo[3,4-d]pyrimidinyl]thio]-1-(1-pyrrolidinyl)ethanone
  • 2-[[4-amino-3-methyl-5-(m-tolyl)pyrazolo[3,4-d]pyrimidin-6-yl]thio]-1-pyrrolidino-ethanone
  • MLS000521277
  • SMR000131685
  • cid_5068278
BDBM100033
PNG
00010000
  • Kallikrein 7
  • 2-(benzalamino)benzamide
  • 2-(benzylideneamino)benzamide
  • 2-[(phenylmethylene)amino]benzamide
  • 2-[(phenylmethylidene)amino]benzamide
  • MLS000532040
  • SMR000136982
  • cid_794805
BDBM100034
PNG
00010000
  • Kallikrein 7
  • 2-[(4-methylbenzylidene)amino]benzamide
  • 2-[(4-methylphenyl)methylideneamino]benzamide
  • MLS000532027
  • SMR000136969
  • cid_794384
BDBM100035
PNG
00010000
  • Kallikrein 7
  • 3-nitrobenzoic acid [4-methoxy-2-[(E)-1-oxo-3-thiophen-2-ylprop-2-enyl]phenyl] ester
  • 3-nitrobenzoic acid [4-methoxy-2-[(E)-3-(2-thienyl)acryloyl]phenyl] ester
  • 4-methoxy-2-[3-(2-thienyl)acryloyl]phenyl 3-nitrobenzoate
  • MLS000534539
  • SMR000141976
  • [4-methoxy-2-[(E)-3-thiophen-2-ylprop-2-enoyl]phenyl] 3-nitrobenzoate
  • cid_5734470
BDBM100036
PNG
00010000
  • Kallikrein 7
  • 1'-acetyl-6-[2-(4-ethyl-1-piperazinyl)-2-oxoethoxy]-4-spiro[3,4-dihydro-2H-1-benzopyran-2,4'-piperidine]one
  • 1'-acetyl-6-[2-(4-ethylpiperazin-1-yl)-2-oxoethoxy]spiro[3H-chromene-2,4'-piperidine]-4-one
  • 1'-acetyl-6-[2-(4-ethylpiperazino)-2-keto-ethoxy]spiro[chroman-2,4'-piperidine]-4-one
  • 1'-ethanoyl-6-[2-(4-ethylpiperazin-1-yl)-2-oxidanylidene-ethoxy]spiro[3H-chromene-2,4'-piperidine]-4-one
  • MLS000519979
  • SMR000130394
  • cid_9551115
BDBM100037
PNG
000100
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