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Targets Binding with 106 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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KiIC50KdEC50koffkonotherITCSDFTSV
1 6-phosphofructo-2-kinaseBDB 6 1 236 0 0 0 0 0 0 0 5 18 2D 3DTSV
2 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3BDB 6 1 163 0 0 0 0 0 0 0 5 8 2D 3DTSV
3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3)BDB 6 1 163 0 0 0 0 0 0 0 5 8 2D 3DTSV
4 6PF-2-K/Fru-2,6-P2ase 3BDB 6 1 163 0 0 0 0 0 0 0 5 8 2D 3DTSV
5 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozymeBDB 6 1 163 0 0 0 0 0 0 0 5 8 2D 3DTSV
6 Fructose-2,6-bisphosphataseBDB 6 1 236 0 0 0 0 0 0 0 5 18 2D 3DTSV
7 High-affinity cAMP-specific and IBMX-insensitive 3 ,5 -cyclic phosphodiesterase 8ABDB 21 12 109 0 0 0 0 0 0 0 38 12 2D 3DTSV
8 iPFK-2BDB 6 1 163 0 0 0 0 0 0 0 5 8 2D 3DTSV
9 LAPBDB 8 23 33 0 0 0 0 0 0 0 5 8 2D 3DTSV
10 Latency-associated peptideEBI 1 0 7 0 0 0 0 0 0 0 1 5 2D 3DTSV
11 NLRP3 proteinBDB 42 0 166 0 12 0 0 0 0 0 8 16 2D 3DTSV
12 PDE8ABDB 21 12 109 0 0 0 0 0 0 0 38 12 2D 3DTSV
13 PFK/FBPase 3BDB 6 1 163 0 0 0 0 0 0 0 5 8 2D 3DTSV
14 PFKFB3BDB 6 1 163 0 0 0 0 0 0 0 5 8 2D 3DTSV
15 Phosphodiesterase 8 (PDE8)BDB 21 12 109 0 0 0 0 0 0 0 38 12 2D 3DTSV
16 Phosphodiesterase 8A (PDE8A)BDB 21 12 109 0 0 0 0 0 0 0 38 12 2D 3DTSV
17 Phosphodiesterase 8A (PDE8A1)BDB 21 12 109 0 0 0 0 0 0 0 38 12 2D 3DTSV
18 Phosphodiesterase 8A1BDB 21 12 109 0 0 0 0 0 0 0 38 12 2D 3DTSV
19 Phosphodiesterase Type 8 (PDE8A)BDB 21 12 109 0 0 0 0 0 0 0 38 12 2D 3DTSV
20 Renal carcinoma antigen NY-REN-56BDB 6 1 163 0 0 0 0 0 0 0 5 8 2D 3DTSV
21 TGF-beta-1EBI 1 0 7 0 0 0 0 0 0 0 1 5 2D 3DTSV
22 Transforming growth factor beta-1EBI 1 0 7 0 0 0 0 0 0 0 1 5 2D 3DTSV
23 Tumor susceptibility gene 101 proteinEBI 0 4 57 50 0 0 0 0 0 0 3 3 2D 3DTSV
Sub total2601212816501200000
Total2999