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Targets Binding with 125 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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AffyNet
KiIC50KdEC50koffkonotherITCSDFTSV
1 5''-AMP-activated protein kinase catalytic subunit alpha-1 (AMPKa1)BDB 80 0 6 132 40 0 0 0 0 0 18 8 2D 3DTSV
2 5''-AMP-activated protein kinase subunit alpha-1BDB 80 0 6 132 40 0 0 0 0 0 18 8 2D 3DTSV
3 5'-AMP-activated protein kinase catalytic subunit alpha-1BDB 80 0 6 132 40 0 0 0 0 0 18 8 2D 3DTSV
4 ACACA kinaseBDB 80 0 6 132 40 0 0 0 0 0 18 8 2D 3DTSV
5 AMP-activated protein kinase, alpha-1 subunitBDB 81 0 6 132 41 0 0 0 0 0 19 9 2D 3DTSV
6 AMPK subunit alpha-1BDB 80 0 6 132 40 0 0 0 0 0 18 8 2D 3DTSV
7 AMPK-alpha1BDB 80 0 6 132 40 0 0 0 0 0 18 8 2D 3DTSV
8 E3 ubiquitin-protein ligase TRIM24EBI 1 0 67 4 23 0 0 0 0 0 5 5 2D 3DTSV
9 E3 ubiquitin-protein ligase TRIM33EBI 1 0 2 0 0 0 0 0 0 0 1 8 2D 3DTSV
10 Ectodermin homologEBI 1 0 2 0 0 0 0 0 0 0 1 8 2D 3DTSV
11 Elongation of very long chain fatty acids protein 6EBI 8 0 146 0 0 0 0 0 0 0 4 6 2D 3DTSV
12 GABA BEBI 1 98 73 0 5 0 0 0 0 0 26 18 2D 3DTSV
13 GABA-B receptor 1BDB 2 98 78 0 5 0 0 0 0 0 27 19 2D 3DTSV
14 GABA-B-R1BDB 2 4 6 0 5 0 0 0 0 0 6 14 2D 3DTSV
15 Gb1BDB 2 4 6 0 5 0 0 0 0 0 6 14 2D 3DTSV
16 Hydroxymethylglutaryl-CoA reductase kinaseBDB 80 0 6 132 40 0 0 0 0 0 18 8 2D 3DTSV
17 KIAA1113 EBI 1 0 2 0 0 0 0 0 0 0 1 8 2D 3DTSV
18 MRCK alphaBDB 80 5 37 126 0 0 0 0 0 0 16 11 2D 3DTSV
19 MRCKABDB 80 5 37 126 0 0 0 0 0 0 16 11 2D 3DTSV
20 Myotonic dystrophy kinase-related CDC42-binding kinase alphaBDB 80 5 37 126 0 0 0 0 0 0 16 11 2D 3DTSV
21 PKN1EBI 82 0 45 126 0 0 0 0 0 0 20 9 2D 3DTSV
22 Protein kinase N1EBI 82 0 45 126 0 0 0 0 0 0 20 9 2D 3DTSV
23 Protein Rfg7EBI 1 0 2 0 0 0 0 0 0 0 1 8 2D 3DTSV
24 Pyruvate dehydrogenase kinase 4 (PDK4)BDB 0 0 11 0 0 0 0 0 0 0 4 1 2D 3DTSV
25 Pyruvate dehydrogenase kinase isoform 4BDB 0 0 11 0 0 0 0 0 0 0 4 1 2D 3DTSV
26 RET-fused gene 7 proteinEBI 1 0 2 0 0 0 0 0 0 0 1 8 2D 3DTSV
27 RFG7EBI 1 0 2 0 0 0 0 0 0 0 1 8 2D 3DTSV
28 RING finger protein 82EBI 1 0 67 4 23 0 0 0 0 0 5 5 2D 3DTSV
29 RNF82 EBI 1 0 67 4 23 0 0 0 0 0 5 5 2D 3DTSV
30 Serine/threonine-protein kinase MRCK alphaBDB 80 5 37 126 0 0 0 0 0 0 16 11 2D 3DTSV
31 Serine/threonine-protein kinase MRCK-ABDB 80 5 37 126 0 0 0 0 0 0 16 11 2D 3DTSV
32 Tau-protein kinase PRKAA1BDB 80 0 6 132 40 0 0 0 0 0 18 8 2D 3DTSV
33 TIF1EBI 1 0 67 4 23 0 0 0 0 0 5 5 2D 3DTSV
34 TIF1-alphaEBI 1 0 67 4 23 0 0 0 0 0 5 5 2D 3DTSV
35 TIF1-gammaEBI 1 0 2 0 0 0 0 0 0 0 1 8 2D 3DTSV
36 TIF1AEBI 1 0 67 4 23 0 0 0 0 0 5 5 2D 3DTSV
37 TIF1GEBI 1 0 2 0 0 0 0 0 0 0 1 8 2D 3DTSV
38 Transcription intermediary factor 1-alphaEBI 1 0 67 4 23 0 0 0 0 0 5 5 2D 3DTSV
39 Transcription intermediary factor 1-gammaEBI 1 0 2 0 0 0 0 0 0 0 1 8 2D 3DTSV
40 TRIM24EBI 1 0 67 4 23 0 0 0 0 0 5 5 2D 3DTSV
41 TRIM33EBI 1 0 2 0 0 0 0 0 0 0 1 8 2D 3DTSV
42 Tripartite motif-containing protein 24EBI 1 0 67 4 23 0 0 0 0 0 5 5 2D 3DTSV
43 Tripartite motif-containing protein 33EBI 1 0 2 0 0 0 0 0 0 0 1 8 2D 3DTSV
Sub total13202291285210658800000
Total4208