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Targets Binding with 13 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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AffyNet
KiIC50KdEC50koffkonotherITCSDFTSV
1 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1EBI 8 0 19 0 0 0 0 0 0 0 1 3 2D 3DTSV
2 15-Lipoxygenase (SLO)BDB 0 10 13 0 0 0 0 0 0 0 1 3 2D 3DTSV
3 25 kDa brain-specific proteinEBI 2 0 0 0 11 0 0 0 0 0 1 5 2D 3DTSV
4 27 kDa prosomal proteinEBI 0 0 0 0 14 0 0 0 0 0 1 7 2D 3DTSV
5 5-methyltetrahydrofolate--homocysteine methyltransferaseEBI 0 0 13 0 0 0 0 0 0 0 1 8 2D 3DTSV
6 Adapter protein GRB2EBI 1 0 16 0 0 0 0 0 0 0 1 3 2D 3DTSV
7 AdoMet synthetase 1EBI 5 20 0 0 0 0 0 0 0 0 3 3 2D 3DTSV
8 AMP deaminase 1BDB 0 7 6 0 0 0 0 0 0 0 4 7 2D 3DTSV
9 AMP deaminase 1 BDB 0 6 5 0 0 0 0 0 0 0 3 7 2D 3DTSV
10 AMP deaminase 1 (hAMPD1)BDB 0 6 5 0 0 0 0 0 0 0 3 7 2D 3DTSV
11 AMP deaminase isoform MBDB 0 7 6 0 0 0 0 0 0 0 4 7 2D 3DTSV
12 Anthranilate synthase component 1EBI 2 21 0 0 0 0 0 0 0 0 1 1 2D 3DTSV
13 ATP-dependent clamp loader gamma -complexBDB 0 13 0 0 0 0 0 0 0 0 1 4 2D 3DTSV
14 ATP-dependent clamp loaders gp44/62BDB 0 13 0 0 0 0 0 0 0 0 1 2 2D 3DTSV
15 B-cell receptor CD22EBI 1 0 14 0 0 0 0 0 0 0 2 9 2D 3DTSV
16 B-lymphocyte cell adhesion moleculeEBI 1 0 14 0 0 0 0 0 0 0 2 9 2D 3DTSV
17 BL-CAMEBI 1 0 14 0 0 0 0 0 0 0 2 9 2D 3DTSV
18 cAMP-dependent protein kinaseBDB 10 0 3 0 19 0 0 0 0 0 3 4 2D 3DTSV
19 cAMP-dependent protein kinase type I-alpha regulatory subunitBDB 10 0 3 0 19 0 0 0 0 0 3 4 2D 3DTSV
20 cAMP-GEFIEBI 1 0 16 0 0 0 0 0 0 0 3 6 2D 3DTSV
21 cAMP-regulated guanine nucleotide exchange factor IEBI 1 0 16 0 0 0 0 0 0 0 3 6 2D 3DTSV
22 CD167 antigen-like family member BBDB 13 0 0 13 0 0 0 0 0 0 1 0 2D 3DTSV
23 CD45-APEBI 4 6 7 0 0 0 0 0 0 0 3 5 2D 3DTSV
24 CD45-associated proteinEBI 4 6 7 0 0 0 0 0 0 0 3 5 2D 3DTSV
25 CD_antigen=CD22EBI 1 0 14 0 0 0 0 0 0 0 2 9 2D 3DTSV
26 cellular retinoic acid binding protein 1EBI 3 0 21 0 0 0 0 0 0 0 3 4 2D 3DTSV
27 CGEF1EBI 1 0 16 0 0 0 0 0 0 0 3 6 2D 3DTSV
28 Chemokine CXCL12BDB 4 0 4 10 0 0 0 0 0 0 3 11 2D 3DTSV
29 Cholinergic, Nicotinic Alpha6Beta3Beta4Alpha5EBI 6 13 0 0 0 0 0 0 0 0 1 9 2D 3DTSV
30 CHRM4 proteinEBI 9 17 0 0 0 0 0 0 0 0 2 1 2D 3DTSV
31 CytovillinBDB 0 0 0 13 0 0 0 0 0 0 2 7 2D 3DTSV
32 DDOST 48 kDa subunitEBI 0 13 0 0 0 0 0 0 0 0 1 9 2D 3DTSV
33 DLK-1EBI 7 4 2 8 0 0 0 0 0 0 4 4 2D 3DTSV
34 DNA methyltransferase MmuIEBI 12 0 13 2 0 0 0 0 0 0 1 6 2D 3DTSV
35 DNA MTase MmuIEBI 12 0 13 2 0 0 0 0 0 0 1 6 2D 3DTSV
36 DNA polymerase III subunit gammaBDB 0 13 0 0 0 0 0 0 0 0 1 4 2D 3DTSV
37 Dnmt EBI 12 0 13 2 0 0 0 0 0 0 1 6 2D 3DTSV
38 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunitEBI 0 13 0 0 0 0 0 0 0 0 1 9 2D 3DTSV
39 Endothelin-converting enzyme 2BDB 7 7 14 0 0 0 0 0 0 0 3 10 2D 3DTSV
40 Endothelin-converting enzyme 2 (ECE-2)BDB 7 7 14 0 0 0 0 0 0 0 3 10 2D 3DTSV
41 Endothelin-converting enzyme 2 (ECE2)BDB 7 7 14 0 0 0 0 0 0 0 3 10 2D 3DTSV
42 Endothelin-converting enzyme 2 regionBDB 7 7 14 0 0 0 0 0 0 0 3 10 2D 3DTSV
43 Envelope glycoprotein gp70EBI 0 0 13 0 0 0 0 0 0 0 1 1 2D 3DTSV
44 Eosinophil-derived neurotoxin (EDN)BDB 3 13 11 0 0 0 0 0 0 0 3 5 2D 3DTSV
45 EPACEBI 1 0 16 0 0 0 0 0 0 0 3 6 2D 3DTSV
46 EPAC 1EBI 1 0 16 0 0 0 0 0 0 0 3 6 2D 3DTSV
47 EPAC1EBI 1 0 16 0 0 0 0 0 0 0 3 6 2D 3DTSV
48 ESS1BDB 1 0 13 0 0 0 0 0 0 0 1 3 2D 3DTSV
49 Exchange factor directly activated by cAMP 1EBI 1 0 16 0 0 0 0 0 0 0 3 6 2D 3DTSV
50 Exchange protein directly activated by cAMP 1EBI 1 0 16 0 0 0 0 0 0 0 3 6 2D 3DTSV
51 EZRBDB 0 0 0 13 0 0 0 0 0 0 2 7 2D 3DTSV
52 EzrinBDB 0 0 0 13 0 0 0 0 0 0 2 7 2D 3DTSV
53 FA1EBI 7 4 2 8 0 0 0 0 0 0 4 4 2D 3DTSV
54 Fetal antigen 1EBI 7 4 2 8 0 0 0 0 0 0 4 4 2D 3DTSV
55 GABA receptor subunitEBI 0 0 13 0 0 0 0 0 0 0 1 3 2D 3DTSV
56 GAHEBI 7 12 1 0 0 0 0 0 0 0 6 6 2D 3DTSV
57 gamma-Aminobutyric Acid Type B ReceptorBDB 3 16 0 0 16 0 0 0 0 0 1 1 2D 3DTSV
58 Gastric inhibitory polypeptideEBI 0 0 13 0 0 0 0 0 0 0 1 4 2D 3DTSV
59 GuanaseEBI 7 12 1 0 0 0 0 0 0 0 6 6 2D 3DTSV
60 Guanine aminaseEBI 7 12 1 0 0 0 0 0 0 0 6 6 2D 3DTSV
61 Guanine aminohydrolaseEBI 7 12 1 0 0 0 0 0 0 0 6 6 2D 3DTSV
62 Guanine deaminaseEBI 7 12 1 0 0 0 0 0 0 0 6 6 2D 3DTSV
63 Hepatocyte growth factor receptor (HGFR)BDB 3 0 13 0 0 0 0 0 0 0 1 0 2D 3DTSV
64 High affinity immunoglobulin gamma Fc receptor IEBI 1 0 13 0 0 0 0 0 0 0 8 6 2D 3DTSV
65 Inosine-5'-monophosphate dehydrogenase 2EBI 1 4 9 0 0 0 0 0 0 0 4 4 2D 3DTSV
66 Isochorismate synthase entCEBI 2 13 0 0 0 0 0 0 0 0 1 5 2D 3DTSV
67 Ketopantoate reductaseEBI 7 6 0 12 0 0 0 0 0 0 1 5 2D 3DTSV
68 LeukolysinBDB 1 2 11 0 0 0 0 0 0 0 5 4 2D 3DTSV
69 LMP10EBI 1 0 21 0 0 0 0 0 0 0 1 4 2D 3DTSV
70 Low molecular mass protein 10EBI 1 0 21 0 0 0 0 0 0 0 1 4 2D 3DTSV
71 Lymphocyte phosphatase-associated phosphoproteinEBI 4 6 7 0 0 0 0 0 0 0 3 5 2D 3DTSV
72 Macropain iota chainEBI 0 0 0 0 14 0 0 0 0 0 1 7 2D 3DTSV
73 Macropain subunit MECl-1EBI 1 0 21 0 0 0 0 0 0 0 1 4 2D 3DTSV
74 MAT 1EBI 5 20 0 0 0 0 0 0 0 0 3 3 2D 3DTSV
75 MAT-I/IIIEBI 5 20 0 0 0 0 0 0 0 0 3 3 2D 3DTSV
76 Matrix metalloproteinase-25BDB 1 2 11 0 0 0 0 0 0 0 5 4 2D 3DTSV
77 MECL1EBI 1 0 21 0 0 0 0 0 0 0 1 4 2D 3DTSV
78 Membrane-type matrix metalloproteinase 6BDB 1 2 11 0 0 0 0 0 0 0 5 4 2D 3DTSV
79 Membrane-type-6 matrix metalloproteinaseBDB 1 2 11 0 0 0 0 0 0 0 5 4 2D 3DTSV
80 Membrane-type-6 matrix metalloproteinase (MT6-MMP)BDB 1 2 11 0 0 0 0 0 0 0 5 4 2D 3DTSV
81 Metallo-beta-lactamaseBDB 2 0 13 0 0 0 0 0 0 0 1 1 2D 3DTSV
82 Methionine adenosyltransferase 1EBI 5 20 0 0 0 0 0 0 0 0 3 3 2D 3DTSV
83 Methionine adenosyltransferase I/IIIEBI 5 20 0 0 0 0 0 0 0 0 3 3 2D 3DTSV
84 Methionine synthaseEBI 0 0 13 0 0 0 0 0 0 0 1 8 2D 3DTSV
85 MMP-25BDB 1 2 11 0 0 0 0 0 0 0 5 4 2D 3DTSV
86 MSEBI 0 0 13 0 0 0 0 0 0 0 1 8 2D 3DTSV
87 MT-MMP 6BDB 1 2 11 0 0 0 0 0 0 0 5 4 2D 3DTSV
88 MT6-MMPBDB 1 2 11 0 0 0 0 0 0 0 5 4 2D 3DTSV
89 MT6MMPBDB 1 2 11 0 0 0 0 0 0 0 5 4 2D 3DTSV
90 MTMMP6BDB 1 2 11 0 0 0 0 0 0 0 5 4 2D 3DTSV
91 MTREBI 0 0 13 0 0 0 0 0 0 0 1 8 2D 3DTSV
92 Mu-opioid receptorEBI 1 0 12 1 0 0 0 0 0 0 2 0 2D 3DTSV
93 Multicatalytic endopeptidase complex iota chainEBI 0 0 0 0 14 0 0 0 0 0 1 7 2D 3DTSV
94 Multicatalytic endopeptidase complex subunit MECl-1EBI 1 0 21 0 0 0 0 0 0 0 1 4 2D 3DTSV
95 MurE (M. tuberculosis)BDB 0 0 2 0 0 0 0 0 0 0 1 5 2D 3DTSV
96 Myoadenylate deaminaseBDB 0 7 6 0 0 0 0 0 0 0 4 7 2D 3DTSV
97 Na(+)/citrate cotransporterEBI 0 0 34 0 0 0 0 0 0 0 1 9 2D 3DTSV
98 NaCTEBI 0 0 34 0 0 0 0 0 0 0 1 9 2D 3DTSV
99 Neurotrophic tyrosine kinase, receptor-related 3BDB 13 0 0 13 0 0 0 0 0 0 1 0 2D 3DTSV
100 Non-secretory ribonucleaseBDB 3 13 11 0 0 0 0 0 0 0 3 5 2D 3DTSV
101 Non-structural protein 5A (NS5A)(L31M)BDB 0 0 0 0 18 0 0 0 0 0 2 0 2D 3DTSV
102 Oligosaccharyl transferase 48 kDa subunitEBI 0 13 0 0 0 0 0 0 0 0 1 9 2D 3DTSV
103 p27KEBI 0 0 0 0 14 0 0 0 0 0 1 7 2D 3DTSV
104 p51-nedasinEBI 7 12 1 0 0 0 0 0 0 0 6 6 2D 3DTSV
105 p81BDB 0 0 0 13 0 0 0 0 0 0 2 7 2D 3DTSV
106 PAD-H19EBI 1 1 13 0 0 0 0 0 0 0 3 4 2D 3DTSV
107 Parvulin ESS1BDB 1 0 13 0 0 0 0 0 0 0 1 3 2D 3DTSV
108 Peptidylarginine deiminase IIEBI 1 1 13 0 0 0 0 0 0 0 3 4 2D 3DTSV
109 pG2EBI 7 4 2 8 0 0 0 0 0 0 4 4 2D 3DTSV
110 Phenylalanyl-tRNA synthetase (PheRS)EBI 0 0 26 0 0 0 0 0 0 0 1 2 2D 3DTSV
111 phosphodiesterase 4B2BDB 0 0 13 0 0 0 0 0 0 0 1 0 2D 3DTSV
112 PIN1BDB 1 0 13 0 0 0 0 0 0 0 1 3 2D 3DTSV
113 PME-1EBI 1 0 11 0 0 0 0 0 0 0 1 8 2D 3DTSV
114 Pme1EBI 1 0 11 0 0 0 0 0 0 0 1 8 2D 3DTSV
115 Ppme1EBI 1 0 11 0 0 0 0 0 0 0 1 8 2D 3DTSV
116 PROS-27EBI 0 0 0 0 14 0 0 0 0 0 1 7 2D 3DTSV
117 PROS27EBI 0 0 0 0 14 0 0 0 0 0 1 7 2D 3DTSV
118 Proteasome iota chainEBI 0 0 0 0 14 0 0 0 0 0 1 7 2D 3DTSV
119 Proteasome MECl-1EBI 1 0 21 0 0 0 0 0 0 0 1 4 2D 3DTSV
120 Proteasome subunit alpha type-6EBI 0 0 0 0 14 0 0 0 0 0 1 7 2D 3DTSV
121 Proteasome subunit beta type-10EBI 1 0 21 0 0 0 0 0 0 0 1 4 2D 3DTSV
122 Proteasome subunit beta-2iEBI 1 0 21 0 0 0 0 0 0 0 1 4 2D 3DTSV
123 Protein delta homolog 1EBI 7 4 2 8 0 0 0 0 0 0 4 4 2D 3DTSV
124 protein phosphatase methylesterase 1BDB 3 0 5 0 0 0 0 0 0 0 2 8 2D 3DTSV
125 Protein tyrosine phosphatase receptor type C-associated proteinEBI 4 6 7 0 0 0 0 0 0 0 3 5 2D 3DTSV
126 Protein-arginine deiminase type IIEBI 1 1 13 0 0 0 0 0 0 0 3 4 2D 3DTSV
127 Protein-arginine deiminase type-2EBI 1 1 13 0 0 0 0 0 0 0 3 4 2D 3DTSV
128 PSMA6EBI 0 0 0 0 14 0 0 0 0 0 1 7 2D 3DTSV
129 PSMB10EBI 1 0 21 0 0 0 0 0 0 0 1 4 2D 3DTSV
130 PTF1BDB 1 0 13 0 0 0 0 0 0 0 1 3 2D 3DTSV
131 PTPRC-associated proteinEBI 4 6 7 0 0 0 0 0 0 0 3 5 2D 3DTSV
132 Rap guanine nucleotide exchange factor 3EBI 1 0 16 0 0 0 0 0 0 0 3 6 2D 3DTSV
133 Rap1 guanine-nucleotide-exchange factor directly activated by cAMPEBI 1 0 16 0 0 0 0 0 0 0 3 6 2D 3DTSV
134 RAPGEF3EBI 1 0 16 0 0 0 0 0 0 0 3 6 2D 3DTSV
135 Receptor protein-tyrosine kinase erbB-2EBI 1 0 14 0 0 0 0 0 0 0 1 3 2D 3DTSV
136 Receptor protein-tyrosine kinase TKTBDB 13 0 0 13 0 0 0 0 0 0 1 0 2D 3DTSV
137 Receptor-histidine kinase AgrCEBI 0 0 30 0 4 0 0 0 0 0 1 0 2D 3DTSV
138 RNAse 2BDB 3 13 11 0 0 0 0 0 0 0 3 5 2D 3DTSV
139 S-adenosylmethionine synthetase alpha and beta formsEBI 5 20 0 0 0 0 0 0 0 0 3 3 2D 3DTSV
140 S-adenosylmethionine synthetase isoform type-1EBI 5 20 0 0 0 0 0 0 0 0 3 3 2D 3DTSV
141 Serine protease NS5A (L31M)BDB 0 0 0 0 18 0 0 0 0 0 2 0 2D 3DTSV
142 SH2/SH3 adapter GRB2EBI 1 0 16 0 0 0 0 0 0 0 1 3 2D 3DTSV
143 Sialic acid-binding Ig-like lectin 2EBI 1 0 14 0 0 0 0 0 0 0 2 9 2D 3DTSV
144 Siglec-2EBI 1 0 14 0 0 0 0 0 0 0 2 9 2D 3DTSV
145 SLC13A5EBI 0 0 30 0 0 0 0 0 0 0 1 7 2D 3DTSV
146 Sodium-coupled citrate transporterEBI 0 0 34 0 0 0 0 0 0 0 1 9 2D 3DTSV
147 Sodium-dependent citrate transporterEBI 0 0 34 0 0 0 0 0 0 0 1 9 2D 3DTSV
148 Solute carrier family 13 member 5EBI 0 0 34 0 0 0 0 0 0 0 1 9 2D 3DTSV
149 T-cell surface antigen Leu-14EBI 1 0 14 0 0 0 0 0 0 0 2 9 2D 3DTSV
150 TPPPEBI 2 0 0 0 11 0 0 0 0 0 1 5 2D 3DTSV
151 Tubulin polymerization-promoting proteinBDB 3 0 6 0 11 0 0 0 0 0 2 7 2D 3DTSV
152 Tyrosine Kinase DDR2BDB 13 0 0 13 0 0 0 0 0 0 1 0 2D 3DTSV
153 Tyrosine kinase receptor c-Met (c-Met)BDB 3 0 13 0 0 0 0 0 0 0 1 0 2D 3DTSV
154 Tyrosine-protein kinase TYRO10BDB 13 0 0 13 0 0 0 0 0 0 1 0 2D 3DTSV
155 Ubiquitin-specific peptidase 2a (USP2a)BDB 0 0 23 0 0 0 0 0 0 0 1 0 2D 3DTSV
156 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligaseBDB 0 0 14 0 0 0 0 0 0 0 2 6 2D 3DTSV
157 VIL2BDB 0 0 0 13 0 0 0 0 0 0 2 7 2D 3DTSV
158 Villin-2BDB 0 0 0 13 0 0 0 0 0 0 2 7 2D 3DTSV
159 Vitamin-B12 dependent methionine synthaseEBI 0 0 13 0 0 0 0 0 0 0 1 8 2D 3DTSV
160 Vma11pEBI 11 0 0 0 23 0 0 0 0 0 4 4 2D 3DTSV
Sub total417564152221227600000
Total2574