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Targets Binding with 133 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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KiIC50KdEC50koffkonotherITCSDFTSV
1 Abelson tyrosine-protein kinase 1EBI 4 0 111 0 0 0 0 0 0 0 6 15 2D 3DTSV
2 baculovirus IAP repeat 3 (BIR3) domain of XIAPBDB 2 108 4 38 0 0 0 0 2 0 13 0 2D 3DTSV
3 BIR3 domain of X-linked inhibitor of apoptosis proteinBDB 2 108 4 38 0 0 0 0 2 0 13 0 2D 3DTSV
4 Casein kinase I gamma 2EBI 77 1 40 125 0 0 0 0 0 0 11 5 2D 3DTSV
5 Coagulation factor XIIIEBI 4 0 132 2 0 0 0 0 0 0 8 6 2D 3DTSV
6 CSNK1G2EBI 77 1 40 125 0 0 0 0 0 0 11 5 2D 3DTSV
7 GABA A receptor alpha-4/beta-3/gamma-2EBI 10 67 7 0 8 0 0 0 0 0 12 8 2D 3DTSV
8 GABA receptor alpha-4/beta-3/gamma-2 subunitEBI 8 54 0 0 8 0 0 0 0 0 9 0 2D 3DTSV
9 Malignant T-cell-amplified sequence 1BDB 0 0 82 0 52 0 0 0 0 0 2 4 2D 3DTSV
10 MCT-1BDB 0 0 82 0 52 0 0 0 0 0 2 4 2D 3DTSV
11 MCTS1BDB 0 0 82 0 52 0 0 0 0 0 2 4 2D 3DTSV
12 Multiple copies T-cell malignanciesBDB 0 0 82 0 52 0 0 0 0 0 2 4 2D 3DTSV
13 NAD-dependent protein deacetylase sirtuin-5 (SIRT5)BDB 0 11 148 2 0 0 0 0 0 0 13 9 2D 3DTSV
14 NAD-dependent protein deacylase sirtuin-5, mitochondrialBDB 0 11 148 2 0 0 0 0 0 0 13 9 2D 3DTSV
15 PAI-1/uPABDB 0 0 240 0 0 0 0 0 0 0 1 0 2D 3DTSV
16 protein artemis isoform aBDB 90 0 133 0 0 0 0 0 0 0 1 17 2D 3DTSV
17 Proto-oncogene c-Abl Abl1EBI 4 0 111 0 0 0 0 0 0 0 6 15 2D 3DTSV
18 Regulatory protein SIR2 homolog 5BDB 0 11 148 2 0 0 0 0 0 0 13 9 2D 3DTSV
19 SIR2-like protein 5BDB 0 11 148 2 0 0 0 0 0 0 13 9 2D 3DTSV
20 SIR2L5BDB 0 11 148 2 0 0 0 0 0 0 13 9 2D 3DTSV
21 SIRT5BDB 0 11 148 2 0 0 0 0 0 0 13 9 2D 3DTSV
Sub total278405203834022400040
Total3007