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Targets Binding with 140 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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AffyNet
KiIC50KdEC50koffkonotherITCSDFTSV
1 Activin receptor type-1BEBI 84 0 64 122 0 0 0 0 0 0 13 8 2D 3DTSV
2 ACVR1BEBI 84 0 64 122 0 0 0 0 0 0 13 8 2D 3DTSV
3 Alpha 2B adrenergic receptorEBI 3 3 0 0 0 0 0 0 0 0 1 1 2D 3DTSV
4 Component of peroxynitrite reductase/peroxidase complexBDB 94 5 146 0 0 0 0 0 0 0 3 6 2D 3DTSV
5 Dihydrolipoyl dehydrogenase (Lpd)BDB 94 5 146 0 0 0 0 0 0 0 3 6 2D 3DTSV
6 Dihydrolipoyl dehydrogenase (Lpd) A181VBDB 94 5 146 0 0 0 0 0 0 0 3 6 2D 3DTSV
7 Dihydrolipoyl dehydrogenase (Lpd) A290RBDB 94 5 146 0 0 0 0 0 0 0 3 6 2D 3DTSV
8 Dihydrolipoyl dehydrogenase (Lpd) F269RBDB 94 5 146 0 0 0 0 0 0 0 3 6 2D 3DTSV
9 Dihydrolipoyl dehydrogenase (Lpd) G312A, L313G, L314P, Q315MBDB 94 5 146 0 0 0 0 0 0 0 3 6 2D 3DTSV
10 Dihydrolipoyl dehydrogenase (Lpd) L314PBDB 94 5 146 0 0 0 0 0 0 0 3 6 2D 3DTSV
11 Dihydrolipoyl dehydrogenase (Lpd) N209VBDB 94 5 146 0 0 0 0 0 0 0 3 6 2D 3DTSV
12 Dihydrolipoyl dehydrogenase (Lpd) R147TBDB 94 5 146 0 0 0 0 0 0 0 3 6 2D 3DTSV
13 Dihydrolipoyl dehydrogenase (Lpd) R347SBDB 94 5 146 0 0 0 0 0 0 0 3 6 2D 3DTSV
14 Ephrin type-B receptor 2EBI 99 3 53 145 3 0 0 0 0 0 30 16 2D 3DTSV
15 GAR TfaseBDB 1 61 92 0 0 0 0 0 0 0 30 9 2D 3DTSV
16 GAR transformylaseBDB 3 86 131 1 0 0 0 0 0 0 39 11 2D 3DTSV
17 Glycinamide ribonucleotide formyltransferase (GARFTase)BDB 0 57 92 0 0 0 0 0 0 0 30 8 2D 3DTSV
18 Glycinamide ribonucleotide transformylase (GAR Tfase)BDB 0 57 92 0 0 0 0 0 0 0 30 8 2D 3DTSV
19 Lipoamide Dehydrogenase (Lpd)BDB 94 5 146 0 0 0 0 0 0 0 3 6 2D 3DTSV
20 Phospho-N-acetylmuramoyl-pentapeptide-transferase/UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferaseEBI 2 0 145 0 0 0 0 0 0 0 5 3 2D 3DTSV
21 Thymidylate synthase/GAR transformylase/AICAR transformylaseBDB 0 57 92 0 0 0 0 0 0 0 30 8 2D 3DTSV
Sub total13103792431390300000
Total3203