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Targets Binding with 145 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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KiIC50KdEC50koffkonotherITCSDFTSV
1 Acetyl-coenzyme A transporter 1 (AT1)BDB 0 0 151 0 0 0 0 0 0 0 1 4 2D 3DTSV
2 Acid ceramidaseBDB 0 1 209 0 0 0 0 0 0 0 13 7 2D 3DTSV
3 Acid ceramidase (AC)BDB 0 1 209 0 0 0 0 0 0 0 13 7 2D 3DTSV
4 cAMP-dependent Rap1 guanine-nucleotide exchange factorEBI 1 0 50 0 0 0 0 0 0 0 3 6 2D 3DTSV
5 cAMP-GEFIIEBI 10 0 163 0 0 0 0 0 0 0 9 14 2D 3DTSV
6 cAMP-regulated guanine nucleotide exchange factor IIEBI 10 0 163 0 0 0 0 0 0 0 9 14 2D 3DTSV
7 CarboxylesteraseEBI 5 14 167 0 0 0 0 0 0 0 11 4 2D 3DTSV
8 Carboxylesterase 1BDB 120 147 2 0 0 0 0 0 0 0 4 3 2D 3DTSV
9 CGEF2EBI 10 0 113 0 0 0 0 0 0 0 8 9 2D 3DTSV
10 Cgef2 EBI 1 0 50 0 0 0 0 0 0 0 3 6 2D 3DTSV
11 Cholinergic, Nicotinic Alpha3Beta4xEBI 17 77 26 0 94 0 0 0 0 0 20 9 2D 3DTSV
12 Deubiquitinating enzyme 7EBI 6 0 139 3 23 0 0 0 0 0 10 5 2D 3DTSV
13 DNA polymerase IIIBDB 8 153 0 0 0 0 0 0 0 0 6 1 2D 3DTSV
14 DNA polymerase III DnaEBDB 0 27 0 0 0 0 0 0 0 0 2 1 2D 3DTSV
15 DNA polymerase III subunit alphaBDB 0 24 0 0 0 0 0 0 0 0 2 1 2D 3DTSV
16 DNA polymerase IIICBDB 8 153 0 0 0 0 0 0 0 0 6 1 2D 3DTSV
17 DNA polymerase IIIEBDB 0 51 0 0 0 0 0 0 0 0 2 3 2D 3DTSV
18 EPAC 2EBI 10 0 163 0 0 0 0 0 0 0 9 14 2D 3DTSV
19 EPAC2EBI 10 0 113 0 0 0 0 0 0 0 8 9 2D 3DTSV
20 Exchange factor directly activated by cAMP 2EBI 10 0 163 0 0 0 0 0 0 0 9 14 2D 3DTSV
21 Exchange protein directly activated by cAMP 2EBI 10 0 163 0 0 0 0 0 0 0 9 14 2D 3DTSV
22 HAUSPEBI 6 0 139 3 23 0 0 0 0 0 10 5 2D 3DTSV
23 Herpesvirus-associated ubiquitin-specific proteaseEBI 6 0 139 3 23 0 0 0 0 0 10 5 2D 3DTSV
24 liver carboxylesterase 1BDB 120 147 2 0 0 0 0 0 0 0 4 3 2D 3DTSV
25 NS3BDB 64 0 146 0 0 0 0 0 0 0 2 1 2D 3DTSV
26 PolIIIBDB 8 153 0 0 0 0 0 0 0 0 6 1 2D 3DTSV
27 Rap guanine nucleotide exchange factor 4EBI 10 0 163 0 0 0 0 0 0 0 9 14 2D 3DTSV
28 Rapgef4EBI 1 0 50 0 0 0 0 0 0 0 3 6 2D 3DTSV
29 rCEBDB 120 147 2 0 0 0 0 0 0 0 4 3 2D 3DTSV
30 S-Adenosylmethionine Decarboxylase (AdoMetDC)BDB 1 22 123 0 0 0 0 9 0 0 6 6 2D 3DTSV
31 SAMDCBDB 1 22 123 0 0 0 0 9 0 0 6 6 2D 3DTSV
32 Ubiquitin carboxyl-terminal hydrolase 7EBI 6 0 139 3 23 0 0 0 0 0 10 5 2D 3DTSV
33 Ubiquitin thioesterase 7EBI 6 0 139 3 23 0 0 0 0 0 10 5 2D 3DTSV
34 Ubiquitin-specific-processing protease 7EBI 6 0 139 3 23 0 0 0 0 0 10 5 2D 3DTSV
35 USP7EBI 6 0 139 3 23 0 0 0 0 0 10 5 2D 3DTSV
Sub total5971139348721255001800
Total4920