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Targets Binding with 146 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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KiIC50KdEC50koffkonotherITCSDFTSV
1 2.1.1.43BDB 11 107 97 26 4 4 4 0 0 0 21 6 2D 3DTSV
2 Brain glycogen phosphorylaseEBI 10 184 0 0 0 0 0 0 0 0 4 4 2D 3DTSV
3 DOT1-like proteinBDB 11 107 96 26 4 4 4 0 0 0 20 4 2D 3DTSV
4 DOT1-like protein (Dot1L)BDB 11 107 96 26 4 4 4 0 0 0 20 4 2D 3DTSV
5 DOT1LBDB 11 107 96 26 4 4 4 0 0 0 20 4 2D 3DTSV
6 Enoyl-acyl-carrier protein reductaseEBI 65 56 159 0 0 0 0 0 0 0 11 1 2D 3DTSV
7 Glycogen phosphorylase, brain formEBI 10 184 0 0 0 0 0 0 0 0 4 4 2D 3DTSV
8 H3-K79-HMTaseBDB 11 107 96 26 4 4 4 0 0 0 20 4 2D 3DTSV
9 HepsinBDB 12 85 77 0 0 0 0 0 0 0 10 4 2D 3DTSV
10 Histone H3-K79 methyltransferaseBDB 11 107 96 26 4 4 4 0 0 0 20 4 2D 3DTSV
11 Histone H3-K79 methyltransferase (DOT1L)BDB 11 107 105 26 4 4 4 0 0 0 21 4 2D 3DTSV
12 Histone Methyltransferase DOT1LBDB 11 107 96 26 4 4 4 0 0 0 20 4 2D 3DTSV
13 Histone-lysine N-methyltransferase, H3 lysine-79 specificBDB 11 107 96 26 4 4 4 0 0 0 20 4 2D 3DTSV
14 Histone-lysine N-methyltransferase, H3 lysine-79 specific (DOT1L)BDB 11 107 96 26 4 4 4 0 0 0 20 4 2D 3DTSV
15 KIAA1814BDB 11 107 96 26 4 4 4 0 0 0 20 4 2D 3DTSV
16 KMT4BDB 11 107 96 26 4 4 4 0 0 0 20 4 2D 3DTSV
17 Lysine N-methyltransferase 4BDB 11 107 96 26 4 4 4 0 0 0 20 4 2D 3DTSV
18 Serine protease hepsinBDB 12 85 77 0 0 0 0 0 0 0 10 4 2D 3DTSV
19 Transmembrane protease, serine 1BDB 12 85 77 0 0 0 0 0 0 0 10 4 2D 3DTSV
Sub total264207016483385200000
Total4108