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Targets Binding with 15 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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AffyNet
KiIC50KdEC50koffkonotherITCSDFTSV
1 15-Lipoxygenase (LoxA)BDB 12 0 15 0 0 0 0 0 0 0 1 0 2D 3DTSV
2 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1EBI 1 13 2 0 0 0 0 0 0 0 1 5 2D 3DTSV
3 3-beta-HSD IEBI 1 13 2 0 0 0 0 0 0 0 1 5 2D 3DTSV
4 3-beta-hydroxy-5-ene steroid dehydrogenaseEBI 1 13 2 0 0 0 0 0 0 0 1 5 2D 3DTSV
5 3-beta-hydroxy-Delta(5)-steroid dehydrogenaseEBI 1 13 2 0 0 0 0 0 0 0 1 5 2D 3DTSV
6 3-beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type IEBI 1 13 2 0 0 0 0 0 0 0 1 5 2D 3DTSV
7 3-oxoacyl-acyl-carrier protein reductaseEBI 14 6 14 0 0 0 0 0 0 0 2 0 2D 3DTSV
8 78 kDa glucose-regulated proteinEBI 3 0 1 14 0 14 0 0 6 0 2 7 2D 3DTSV
9 AADCEBI 2 0 15 0 0 0 0 0 0 0 1 8 2D 3DTSV
10 Acetylpolyamine amidohydrolase (APAH)BDB 0 0 15 0 0 0 0 0 0 0 3 1 2D 3DTSV
11 Acetylpolyamine aminohydrolaseBDB 0 0 15 0 0 0 0 0 0 0 3 1 2D 3DTSV
12 AfChiB1BDB 4 2 15 3 0 0 0 0 0 0 5 3 2D 3DTSV
13 ALX receptor and the G-protein Gα16EBI 0 0 0 0 15 0 0 0 0 0 1 1 2D 3DTSV
14 Aminoglycoside acetyltransferaseEBI 0 15 0 0 0 0 0 0 0 0 1 0 2D 3DTSV
15 Apoptosis inhibitor 2BDB 0 10 5 0 0 0 0 0 0 0 3 0 2D 3DTSV
16 Aralkylamine N-acetyltransferaseBDB 0 7 8 0 0 0 0 0 0 0 2 5 2D 3DTSV
17 Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferaseEBI 0 0 31 0 0 0 0 0 0 0 3 6 2D 3DTSV
18 Beta-lactamase 2EBI 2 2 13 0 0 0 0 0 0 0 2 1 2D 3DTSV
19 BiPEBI 3 0 1 14 0 14 0 0 6 0 2 7 2D 3DTSV
20 Calcium-activated potassium channel subunit alpha-1EBI 1 0 17 0 0 0 0 0 0 0 3 11 2D 3DTSV
21 CALCREBI 0 15 0 0 0 0 0 0 0 0 3 10 2D 3DTSV
22 CDw130EBI 0 0 15 0 0 0 0 0 0 0 1 5 2D 3DTSV
23 CD_antigen=CD130EBI 0 0 15 0 0 0 0 0 0 0 1 5 2D 3DTSV
24 cIAP-2 BIR3BDB 0 10 5 0 0 0 0 0 0 0 3 0 2D 3DTSV
25 Class V chitinase ChiB1BDB 4 2 15 3 0 0 0 0 0 0 5 3 2D 3DTSV
26 Delta-5-3-ketosteroid isomeraseEBI 1 13 2 0 0 0 0 0 0 0 1 5 2D 3DTSV
27 Dengue 2 NS2B(H):NS3BDB 3 5 10 7 0 0 0 0 0 0 2 0 2D 3DTSV
28 Dengue Virus 2 (DENV2) NS2B-NS3 ProteaseBDB 3 5 10 7 0 0 0 0 0 0 2 0 2D 3DTSV
29 Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78EBI 3 0 1 14 0 14 0 0 6 0 2 7 2D 3DTSV
30 GGNT3EBI 0 0 31 0 0 0 0 0 0 0 3 6 2D 3DTSV
31 GlcNAc-T IIIEBI 0 0 31 0 0 0 0 0 0 0 3 6 2D 3DTSV
32 Glucosamine-6- Phosphate SynthaseBDB 1 10 15 0 0 0 0 0 0 0 1 4 2D 3DTSV
33 Glycine Transporter 1 (GlyT1)BDB 0 16 0 0 0 0 0 0 0 0 1 0 2D 3DTSV
34 GNT-IIIEBI 0 0 31 0 0 0 0 0 0 0 3 6 2D 3DTSV
35 GRP-78EBI 3 0 1 14 0 14 0 0 6 0 2 7 2D 3DTSV
36 Grp78EBI 3 0 1 14 0 14 0 0 6 0 2 7 2D 3DTSV
37 Heat sensitive channel TRPV3EBI 0 0 14 0 15 0 0 0 0 0 1 0 2D 3DTSV
38 Heat shock 70 kDa protein 5EBI 3 0 1 14 0 14 0 0 6 0 2 7 2D 3DTSV
39 HEK4BDB 13 0 0 15 0 0 0 0 0 0 2 0 2D 3DTSV
40 hIL-1betaBDB 1 1 14 0 0 0 0 0 9 0 4 8 2D 3DTSV
41 HSPA5EBI 3 0 1 14 0 14 0 0 6 0 2 7 2D 3DTSV
42 IL-6 receptor subunit betaEBI 0 0 15 0 0 0 0 0 0 0 1 5 2D 3DTSV
43 IL-6R subunit betaEBI 0 0 15 0 0 0 0 0 0 0 1 5 2D 3DTSV
44 IL-6R-betaEBI 0 0 15 0 0 0 0 0 0 0 1 5 2D 3DTSV
45 IL-6RBEBI 0 0 15 0 0 0 0 0 0 0 1 5 2D 3DTSV
46 IL6STEBI 0 0 15 0 0 0 0 0 0 0 1 5 2D 3DTSV
47 Immunoglobulin heavy chain-binding proteinEBI 3 0 1 14 0 14 0 0 6 0 2 7 2D 3DTSV
48 Inhibitor of apoptosis protein 1BDB 0 10 5 0 0 0 0 0 0 0 3 0 2D 3DTSV
49 Inositol 1,4,5-trisphosphate receptorEBI 4 1 6 14 4 0 0 0 0 0 5 9 2D 3DTSV
50 Interleukin 1-betaBDB 1 1 14 0 0 0 0 0 9 0 4 8 2D 3DTSV
51 Interleukin-1 betaBDB 1 1 14 0 0 0 0 0 9 0 4 8 2D 3DTSV
52 Interleukin-6 receptor subunit betaEBI 0 0 15 0 0 0 0 0 0 0 1 5 2D 3DTSV
53 Interleukin-6 signal transducerEBI 0 0 15 0 0 0 0 0 0 0 1 5 2D 3DTSV
54 Interlukin-2-inducible tyrosine kinase (Itk)BDB 0 0 16 0 0 0 0 0 0 0 1 0 2D 3DTSV
55 KIAA0071EBI 0 1 15 0 0 0 0 0 0 0 2 0 2D 3DTSV
56 Lysosomal alpha-mannosidaseEBI 3 6 29 0 0 0 0 0 0 0 3 7 2D 3DTSV
57 Membrane glycoprotein 130EBI 0 0 15 0 0 0 0 0 0 0 1 5 2D 3DTSV
58 Metallo-beta-lactamase domain-containing protein 2EBI 2 2 13 0 0 0 0 0 0 0 2 1 2D 3DTSV
59 Metallo-beta-lactamase superfamily proteinEBI 2 2 13 0 0 0 0 0 0 0 2 1 2D 3DTSV
60 MGAT3EBI 0 0 31 0 0 0 0 0 0 0 3 6 2D 3DTSV
61 N-acetylglucosaminyltransferase IIIEBI 0 0 31 0 0 0 0 0 0 0 3 6 2D 3DTSV
62 N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IIIEBI 0 0 31 0 0 0 0 0 0 0 3 6 2D 3DTSV
63 Oncostatin-M receptor subunit alphaEBI 0 0 15 0 0 0 0 0 0 0 1 5 2D 3DTSV
64 Phenylalanyl-tRNA synthetase alpha chainEBI 2 0 42 0 0 0 0 0 0 0 1 1 2D 3DTSV
65 Phospholipid transfer proteinEBI 0 0 15 0 0 0 0 0 0 0 1 10 2D 3DTSV
66 Progesterone reductaseEBI 1 13 2 0 0 0 0 0 0 0 1 5 2D 3DTSV
67 Protein CoRESTEBI 0 1 15 0 0 0 0 0 0 0 2 0 2D 3DTSV
68 RCOREBI 0 1 15 0 0 0 0 0 0 0 2 0 2D 3DTSV
69 RCOR1EBI 0 1 15 0 0 0 0 0 0 0 2 0 2D 3DTSV
70 REST corepressor 1EBI 0 1 15 0 0 0 0 0 0 0 2 0 2D 3DTSV
71 Retinoic acid receptor RXR-alpha/oxysterols receptor LXR-alphaEBI 0 15 0 0 0 0 0 0 0 0 1 2 2D 3DTSV
72 Retinoic acid receptor RXR-alpha/oxysterols receptor LXR-betaEBI 0 15 0 0 0 0 0 0 0 0 1 2 2D 3DTSV
73 Serine/threonine-protein kinase RAF and Dual specificity mitogen-activated protein kinase kinase 1 (Raf/MEK)EBI 0 0 15 0 0 0 0 0 0 0 1 2 2D 3DTSV
74 Serotonin N-acetyltransferase (AANAT)BDB 0 7 8 0 0 0 0 0 0 0 2 5 2D 3DTSV
75 Shikimate kinaseEBI 1 18 2 2 0 0 0 0 0 0 2 1 2D 3DTSV
76 SKEBI 1 18 2 2 0 0 0 0 0 0 2 1 2D 3DTSV
77 skaEBI 5 0 15 0 0 0 0 0 0 0 2 1 2D 3DTSV
78 Small conductance calcium-activated potassium channel protein 2 (KCa2.2)BDB 0 0 14 0 1 0 0 0 0 0 3 1 2D 3DTSV
79 StreptokinaseEBI 5 0 15 0 0 0 0 0 0 0 2 1 2D 3DTSV
80 Succinyl-diaminopimelate desuccinylaseEBI 15 5 15 0 0 0 0 0 0 0 1 1 2D 3DTSV
81 TentoxylysinEBI 0 15 0 0 0 0 0 0 0 0 1 1 2D 3DTSV
82 Testis-specific serine/threonine-protein kinase 2EBI 2 1 15 0 0 0 0 0 0 0 13 3 2D 3DTSV
83 Tetanus toxinEBI 0 15 0 0 0 0 0 0 0 0 1 1 2D 3DTSV
84 Tetanus toxin chain HEBI 0 15 0 0 0 0 0 0 0 0 1 1 2D 3DTSV
85 Tetanus toxin chain LEBI 0 15 0 0 0 0 0 0 0 0 1 1 2D 3DTSV
86 Tetanus toxin heavy chainEBI 0 15 0 0 0 0 0 0 0 0 1 1 2D 3DTSV
87 Tetanus toxin light chainEBI 0 15 0 0 0 0 0 0 0 0 1 1 2D 3DTSV
88 Trophoblast antigen FDO161GEBI 1 13 2 0 0 0 0 0 0 0 1 5 2D 3DTSV
89 Tyrosine Kinase EPHA3BDB 13 0 0 15 0 0 0 0 0 0 2 0 2D 3DTSV
Sub total14940796418035000750
Total1586