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Targets Binding with 17 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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KiIC50KdEC50koffkonotherITCSDFTSV
1 3.5.1.2EBI 0 0 16 0 0 0 0 0 0 0 1 6 2D 3DTSV
2 Activation inducer moleculeEBI 0 0 26 6 0 0 0 0 0 0 3 2 2D 3DTSV
3 Adenylate cyclase type IEBI 1 0 0 17 0 0 0 0 0 0 1 1 2D 3DTSV
4 AIMEBI 0 0 26 6 0 0 0 0 0 0 3 2 2D 3DTSV
5 Betaine--homocysteine S-methyltransferase 1EBI 0 1 19 2 0 0 0 0 0 0 4 4 2D 3DTSV
6 BL-AC/P26EBI 0 0 26 6 0 0 0 0 0 0 3 2 2D 3DTSV
7 BPTFEBI 1 2 6 9 0 0 0 0 0 0 12 5 2D 3DTSV
8 BRD4-BD1-BD2BDB 0 0 17 0 0 0 0 0 0 0 1 0 2D 3DTSV
9 Bromodomain and PHD finger-containing transcription factorEBI 1 2 6 9 0 0 0 0 0 0 12 5 2D 3DTSV
10 C-type lectin domain family 2 member CEBI 0 0 26 6 0 0 0 0 0 0 3 2 2D 3DTSV
11 cAMP-dependent protein kinase type II-beta regulatory subunitEBI 7 0 0 7 19 0 0 0 0 0 3 4 2D 3DTSV
12 CD69EBI 0 0 26 6 0 0 0 0 0 0 3 2 2D 3DTSV
13 CD_antigen=CD69EBI 0 0 26 6 0 0 0 0 0 0 3 2 2D 3DTSV
14 Centromere-associated protein EEBI 1 0 19 0 0 0 0 0 0 0 3 5 2D 3DTSV
15 Cholinergic, Nicotinic MuscleEBI 5 7 3 8 0 0 0 0 0 0 5 3 2D 3DTSV
16 Clathrin heavy chain 1EBI 0 0 17 0 0 0 0 0 0 0 1 5 2D 3DTSV
17 Clathrin heavy chain on chromosome 17EBI 0 0 17 0 0 0 0 0 0 0 1 5 2D 3DTSV
18 CLEC2CEBI 0 0 26 6 0 0 0 0 0 0 3 2 2D 3DTSV
19 CLH-17EBI 0 0 17 0 0 0 0 0 0 0 1 5 2D 3DTSV
20 CLH17EBI 0 0 17 0 0 0 0 0 0 0 1 5 2D 3DTSV
21 CLTCEBI 0 0 17 0 0 0 0 0 0 0 1 5 2D 3DTSV
22 CLTCL2EBI 0 0 17 0 0 0 0 0 0 0 1 5 2D 3DTSV
23 Coagulation factor XIII A (FXIIIa)BDB 0 0 17 0 0 0 0 0 0 0 1 0 2D 3DTSV
24 Cytochrome P450 21 (CYP21)BDB 0 0 34 0 0 0 0 0 0 0 1 3 2D 3DTSV
25 Cytochrome P450-C17 (CYP17A1)BDB 0 0 34 0 0 0 0 0 0 0 1 3 2D 3DTSV
26 DLK-1EBI 7 6 5 8 0 0 0 0 0 0 5 4 2D 3DTSV
27 E1-L2EBI 0 0 17 0 0 0 0 0 0 0 3 13 2D 3DTSV
28 E3 ubiquitin-protein ligase (XIAP-BIR2)(C202A/C213G)BDB 0 0 19 0 0 0 0 0 0 0 1 0 2D 3DTSV
29 EA1EBI 0 0 26 6 0 0 0 0 0 0 3 2 2D 3DTSV
30 Early activation antigen CD69EBI 0 0 26 6 0 0 0 0 0 0 3 2 2D 3DTSV
31 Early T-cell activation antigen p60EBI 0 0 26 6 0 0 0 0 0 0 3 2 2D 3DTSV
32 Erythrocyte 65 kDa proteinEBI 1 1 17 0 3 0 0 0 0 0 6 15 2D 3DTSV
33 FA1EBI 7 6 5 8 0 0 0 0 0 0 5 4 2D 3DTSV
34 FALZEBI 1 2 6 9 0 0 0 0 0 0 12 5 2D 3DTSV
35 Fetal Alz-50 clone 1 proteinEBI 1 2 6 9 0 0 0 0 0 0 12 5 2D 3DTSV
36 Fetal Alzheimer antigenEBI 1 2 6 9 0 0 0 0 0 0 12 5 2D 3DTSV
37 Fetal antigen 1EBI 7 6 5 8 0 0 0 0 0 0 5 4 2D 3DTSV
38 G-protein coupled receptor 104EBI 13 0 0 0 17 0 0 0 0 0 1 7 2D 3DTSV
39 G-protein coupled receptor 81EBI 1 0 0 0 2 0 0 0 0 0 1 2 2D 3DTSV
40 GAEBI 0 0 16 0 0 0 0 0 0 0 1 6 2D 3DTSV
41 Gama-aminobutyric acid (GABA) alpha 2 deltaEBI 0 0 17 0 0 0 0 0 0 0 1 0 2D 3DTSV
42 Gamma hydroxybutyric, GHBEBI 8 4 17 0 0 0 0 0 0 0 4 1 2D 3DTSV
43 Gamma-hydroxybutyrate receptorEBI 8 4 17 0 0 0 0 0 0 0 4 1 2D 3DTSV
44 GIIE sPLA2EBI 1 0 18 0 0 0 0 0 0 0 2 3 2D 3DTSV
45 GLS2EBI 0 0 16 0 0 0 0 0 0 0 1 6 2D 3DTSV
46 Glutamate decarboxylaseBDB 1 10 0 0 0 0 0 0 0 0 3 7 2D 3DTSV
47 Glutaminase liver isoform, mitochondrialEBI 0 0 17 0 0 0 0 0 0 0 2 9 2D 3DTSV
48 Glutamine synthetaseBDB 4 19 8 0 0 0 0 0 0 0 6 16 2D 3DTSV
49 Glycylpeptide N-tetradecanoyltransferase 2EBI 4 16 1 0 0 0 0 0 0 0 2 6 2D 3DTSV
50 GP32/28EBI 0 0 26 6 0 0 0 0 0 0 3 2 2D 3DTSV
51 GPR104EBI 13 0 0 0 17 0 0 0 0 0 1 7 2D 3DTSV
52 Group IIE secretory phospholipase A2EBI 1 0 36 0 0 0 0 0 0 0 2 5 2D 3DTSV
53 H4-BRD4EBI 0 0 17 0 0 0 0 0 0 0 1 0 2D 3DTSV
54 Hao1_mappedEBI 0 0 1 0 0 0 0 0 0 0 1 1 2D 3DTSV
55 HCA1EBI 13 0 0 0 17 0 0 0 0 0 1 7 2D 3DTSV
56 HDAC1/NCOR2EBI 1 0 17 0 0 0 0 0 0 0 1 0 2D 3DTSV
57 HDAC2/NCOR2EBI 1 0 17 0 0 0 0 0 0 0 1 0 2D 3DTSV
58 Histone deacetylase 1/2/3/6EBI 0 0 68 0 0 0 0 0 0 0 1 0 2D 3DTSV
59 hWNK1EBI 1 1 17 0 3 0 0 0 0 0 6 15 2D 3DTSV
60 Hyaluronidase-1EBI 4 0 22 0 0 0 0 0 0 0 2 18 2D 3DTSV
61 Hyaluronoglucosaminidase-1EBI 4 0 22 0 0 0 0 0 0 0 2 18 2D 3DTSV
62 Hydroxyacid oxidase 1 (Mapped)EBI 0 0 1 0 0 0 0 0 0 0 1 1 2D 3DTSV
63 ITGA8/ITGB1BDB 0 0 17 0 0 0 0 0 0 0 1 0 2D 3DTSV
64 KIAA0034EBI 0 0 17 0 0 0 0 0 0 0 1 5 2D 3DTSV
65 Kiaa4146EBI 0 0 1 0 0 0 0 0 0 0 1 4 2D 3DTSV
66 Kinase deficient proteinEBI 1 1 17 0 3 0 0 0 0 0 6 15 2D 3DTSV
67 KynureninaseEBI 6 12 10 0 0 0 0 0 0 0 6 10 2D 3DTSV
68 L-glutaminaseEBI 0 0 17 0 0 0 0 0 0 0 2 9 2D 3DTSV
69 Large neutral amino acids transporter small subunit 2BDB 0 0 17 0 0 0 0 0 0 0 1 12 2D 3DTSV
70 LDL receptorEBI 0 0 0 0 17 0 0 0 0 0 1 13 2D 3DTSV
71 Leukocyte surface antigen Leu-23EBI 0 0 26 6 0 0 0 0 0 0 3 2 2D 3DTSV
72 Low-density lipoprotein receptorEBI 0 0 0 0 17 0 0 0 0 0 1 13 2D 3DTSV
73 LOXEBI 5 0 17 0 0 0 0 0 0 0 1 3 2D 3DTSV
74 Mandelate racemaseBDB 7 23 0 0 0 0 0 0 0 0 5 1 2D 3DTSV
75 Mandelate racemase (MR)BDB 7 23 0 0 0 0 0 0 0 0 5 1 2D 3DTSV
76 MLR-3EBI 0 0 26 6 0 0 0 0 0 0 3 2 2D 3DTSV
77 Modulator of drug activity AEBI 1 0 17 0 0 0 0 0 0 0 1 2 2D 3DTSV
78 Monocyte protein 4EBI 0 0 17 0 0 0 0 0 0 0 3 13 2D 3DTSV
79 MOP-4EBI 0 0 17 0 0 0 0 0 0 0 3 13 2D 3DTSV
80 MOP4EBI 0 0 17 0 0 0 0 0 0 0 3 13 2D 3DTSV
81 Mu opioid receptor-like OR2EBI 1 18 0 0 0 0 0 0 0 0 2 1 2D 3DTSV
82 Myristoyl-CoA:protein N-myristoyltransferase 2EBI 4 16 1 0 0 0 0 0 0 0 2 6 2D 3DTSV
83 Na(+)/I(-) cotransporterEBI 1 0 20 0 0 0 0 0 0 0 1 1 2D 3DTSV
84 Na(+)/I(-) symporterEBI 1 0 20 0 0 0 0 0 0 0 1 1 2D 3DTSV
85 NACHR alpha 9EBI 5 7 3 8 0 0 0 0 0 0 5 3 2D 3DTSV
86 Nicotinic acetylcholine receptor subunit alpha 9EBI 5 7 3 8 0 0 0 0 0 0 5 3 2D 3DTSV
87 NisEBI 1 0 20 0 0 0 0 0 0 0 1 1 2D 3DTSV
88 NMT 2EBI 4 16 1 0 0 0 0 0 0 0 2 6 2D 3DTSV
89 NS3 proteinBDB 1 11 0 0 0 0 0 0 0 0 1 1 2D 3DTSV
90 Nuclear receptor subfamily 2 group C member 1 (NR2C)BDB 0 0 17 0 0 0 0 0 0 0 1 1 2D 3DTSV
91 Nucleosome-remodeling factor subunit BPTFEBI 1 2 6 9 0 0 0 0 0 0 12 5 2D 3DTSV
92 or2EBI 1 18 0 0 0 0 0 0 0 0 2 1 2D 3DTSV
93 p65EBI 1 1 17 0 3 0 0 0 0 0 6 15 2D 3DTSV
94 PALEBI 2 2 30 0 0 0 0 0 0 0 2 12 2D 3DTSV
95 PAMEBI 2 2 30 0 0 0 0 0 0 0 2 12 2D 3DTSV
96 Parathyroid hormone (PTH)BDB 0 0 0 0 17 0 0 0 0 0 1 0 2D 3DTSV
97 Peptide N-myristoyltransferase 2EBI 4 16 1 0 0 0 0 0 0 0 2 6 2D 3DTSV
98 Peptidyl-alpha-hydroxyglycine alpha-amidating lyaseEBI 2 2 30 0 0 0 0 0 0 0 2 12 2D 3DTSV
99 Peptidylamidoglycolate lyaseEBI 2 2 30 0 0 0 0 0 0 0 2 12 2D 3DTSV
100 Peptidylglycine alpha-hydroxylating monooxygenaseEBI 2 2 30 0 0 0 0 0 0 0 2 12 2D 3DTSV
101 pG2EBI 7 6 5 8 0 0 0 0 0 0 5 4 2D 3DTSV
102 PHMEBI 2 2 30 0 0 0 0 0 0 0 2 12 2D 3DTSV
103 Phosphatidylcholine 2-acylhydrolase GIIEEBI 1 0 18 0 0 0 0 0 0 0 2 3 2D 3DTSV
104 PLZFEBI 0 0 17 0 0 0 0 0 0 0 1 4 2D 3DTSV
105 PNAG de-N-acetylase (PgaB)BDB 0 5 15 0 0 0 0 0 0 0 2 5 2D 3DTSV
106 Promyelocytic leukemia zinc finger proteinEBI 0 0 17 0 0 0 0 0 0 0 1 4 2D 3DTSV
107 Protein delta homolog 1EBI 7 6 5 8 0 0 0 0 0 0 5 4 2D 3DTSV
108 Protein Hao1EBI 0 0 1 0 0 0 0 0 0 0 1 1 2D 3DTSV
109 Protein kinase lysine-deficient 1EBI 1 1 17 0 3 0 0 0 0 0 6 15 2D 3DTSV
110 Protein kinase with no lysine 1EBI 1 1 17 0 3 0 0 0 0 0 6 15 2D 3DTSV
111 Protein-lysine 6-oxidaseEBI 5 0 17 0 0 0 0 0 0 0 1 3 2D 3DTSV
112 Serine/threonine-protein kinase WNK1EBI 1 1 17 0 3 0 0 0 0 0 6 15 2D 3DTSV
113 Single chain N-terminally linked NS4a 21-32 NS3 3-631EBI 1 0 4 4 0 0 0 0 0 0 1 0 2D 3DTSV
114 Slc5a5EBI 1 0 20 0 0 0 0 0 0 0 1 1 2D 3DTSV
115 Sodium-iodide symporterEBI 1 0 20 0 0 0 0 0 0 0 1 1 2D 3DTSV
116 Sodium/iodide cotransporterEBI 1 0 20 0 0 0 0 0 0 0 1 1 2D 3DTSV
117 Solute carrier family 5 member 5EBI 1 0 20 0 0 0 0 0 0 0 1 1 2D 3DTSV
118 sPLA(2)-IIEEBI 1 0 18 0 0 0 0 0 0 0 2 3 2D 3DTSV
119 Transcriptional regulator MvfREBI 14 0 0 18 8 0 0 0 0 0 1 1 2D 3DTSV
120 Type II N-myristoyltransferaseEBI 4 16 1 0 0 0 0 0 0 0 2 6 2D 3DTSV
121 UBA6EBI 0 0 17 0 0 0 0 0 0 0 3 13 2D 3DTSV
122 UBE1L2EBI 0 0 17 0 0 0 0 0 0 0 3 13 2D 3DTSV
123 Ubiquitin-activating enzyme 6EBI 0 0 17 0 0 0 0 0 0 0 3 13 2D 3DTSV
124 Ubiquitin-activating enzyme E1-like protein 2EBI 0 0 17 0 0 0 0 0 0 0 3 13 2D 3DTSV
125 Ubiquitin-like modifier-activating enzyme 6EBI 0 0 17 0 0 0 0 0 0 0 3 13 2D 3DTSV
126 ZBTB16EBI 0 0 17 0 0 0 0 0 0 0 1 4 2D 3DTSV
127 Zinc finger and BTB domain-containing protein 16EBI 0 0 17 0 0 0 0 0 0 0 1 4 2D 3DTSV
128 Zinc finger protein 145EBI 0 0 17 0 0 0 0 0 0 0 1 4 2D 3DTSV
129 Zinc finger protein PLZFEBI 0 0 17 0 0 0 0 0 0 0 1 4 2D 3DTSV
130 ZNF145EBI 0 0 17 0 0 0 0 0 0 0 1 4 2D 3DTSV
Sub total235310193124415200000
Total2637