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Targets Binding with 18 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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myBDB

AffyNet
KiIC50KdEC50koffkonotherITCSDFTSV
1 (ARTD8 or PARP14)BDB 3 0 19 2 0 0 0 0 0 0 3 8 2D 3DTSV
2 (ARTD8 or PARP14, Y1660L)BDB 3 0 19 2 0 0 0 0 0 0 3 8 2D 3DTSV
3 4-nitrophenol 2-hydroxylaseBDB 1 3 15 0 0 0 0 0 0 0 3 1 2D 3DTSV
4 ADP-ribosyltransferase diphtheria toxin-like 8BDB 3 0 19 2 0 0 0 0 0 0 3 8 2D 3DTSV
5 ALL-1BDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
6 ALL1 BDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
7 Amine oxidase, copper containingEBI 1 0 18 0 0 0 0 0 0 0 2 6 2D 3DTSV
8 ARTD8BDB 3 0 19 2 0 0 0 0 0 0 3 8 2D 3DTSV
9 B aggressive lymphoma protein 2BDB 3 0 19 2 0 0 0 0 0 0 3 8 2D 3DTSV
10 BAL2BDB 3 0 19 2 0 0 0 0 0 0 3 8 2D 3DTSV
11 BAL2 BDB 3 0 19 2 0 0 0 0 0 0 3 8 2D 3DTSV
12 Beta-hexosaminidase subunit betaBDB 4 17 4 0 0 0 0 0 0 0 4 1 2D 3DTSV
13 Beta-hexosaminidase subunit beta (Hex B)BDB 4 17 4 0 0 0 0 0 0 0 4 1 2D 3DTSV
14 Beta-N-acetylhexosaminidase subunit betaBDB 4 17 4 0 0 0 0 0 0 0 4 1 2D 3DTSV
15 C-terminal cleavage product of 180 kDaBDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
16 CDK6/cyclin D1EBI 6 2 16 0 0 0 0 0 0 0 9 2 2D 3DTSV
17 CXXC-type zinc finger protein 7BDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
18 CXXC7BDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
19 Cyclin-dependent kinase 6/G1/S-specific cyclin D1EBI 6 2 16 0 0 0 0 0 0 0 9 2 2D 3DTSV
20 CYPIIE1BDB 1 3 15 0 0 0 0 0 0 0 3 1 2D 3DTSV
21 DNA polymerase III polC-typeEBI 0 0 18 0 0 0 0 0 0 0 1 6 2D 3DTSV
22 DnaC helicaseEBI 16 0 18 0 0 0 0 0 0 0 1 0 2D 3DTSV
23 Farnesyl synthetase, putativeEBI 0 0 20 0 0 0 0 0 0 0 2 0 2D 3DTSV
24 GABA receptor alpha-6/beta-2/gamma-2 subunitEBI 5 42 0 0 0 0 0 0 0 0 2 3 2D 3DTSV
25 H3-K9-HMTase 1EBI 7 7 14 0 0 0 0 0 0 0 7 6 2D 3DTSV
26 HEXBBDB 4 17 4 0 0 0 0 0 0 0 4 1 2D 3DTSV
27 Hexosaminidase subunit BBDB 4 17 4 0 0 0 0 0 0 0 4 1 2D 3DTSV
28 Histone H3-K9 methyltransferase 1EBI 7 7 14 0 0 0 0 0 0 0 7 6 2D 3DTSV
29 Histone-lysine N-methyltransferase 2ABDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
30 Histone-lysine N-methyltransferase SUV39H1EBI 7 7 14 0 0 0 0 0 0 0 7 6 2D 3DTSV
31 HRXBDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
32 HTRXBDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
33 Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14)BDB 3 0 20 2 0 0 0 0 0 0 4 8 2D 3DTSV
34 Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14, Y1660L)BDB 3 0 19 2 0 0 0 0 0 0 3 8 2D 3DTSV
35 Hyaluronate lyaseEBI 1 0 1 0 0 0 0 0 0 0 1 3 2D 3DTSV
36 HyaluronidaseEBI 5 0 23 0 0 0 0 0 0 0 3 16 2D 3DTSV
37 HYaseEBI 1 0 1 0 0 0 0 0 0 0 1 3 2D 3DTSV
38 integrin alpha-LBDB 13 0 3 0 15 0 0 0 0 0 3 1 2D 3DTSV
39 JAK3/JAK1EBI 4 0 22 0 0 0 0 0 0 0 4 2 2D 3DTSV
40 KIAA1268BDB 3 0 19 2 0 0 0 0 0 0 3 8 2D 3DTSV
41 KMT1AEBI 7 7 14 0 0 0 0 0 0 0 7 6 2D 3DTSV
42 KMT2ABDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
43 Lymphocyte antigen 15BDB 13 0 3 0 15 0 0 0 0 0 3 1 2D 3DTSV
44 Lysine N-methyltransferase 1AEBI 7 7 14 0 0 0 0 0 0 0 7 6 2D 3DTSV
45 Lysine N-methyltransferase 2ABDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
46 Matrix metalloproteinase 12EBI 1 0 18 0 0 0 0 0 0 0 3 17 2D 3DTSV
47 MCT 4EBI 10 0 21 0 0 0 0 0 0 0 1 4 2D 3DTSV
48 MCT4EBI 10 0 21 0 0 0 0 0 0 0 1 4 2D 3DTSV
49 Membrane-bound aminopeptidase P (APP2)BDB 1 0 37 0 0 0 0 0 0 0 3 4 2D 3DTSV
50 MEP2BDB 16 0 0 0 18 0 0 0 0 0 2 3 2D 3DTSV
51 MLL cleavage product C180BDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
52 MLL cleavage product N320BDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
53 MLL1BDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
54 Monocarboxylate transporter 4EBI 10 0 21 0 0 0 0 0 0 0 1 4 2D 3DTSV
55 Myeloid/lymphoid or mixed-lineage leukemiaBDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
56 Myeloid/lymphoid or mixed-lineage leukemia (MLL)BDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
57 Myeloid/lymphoid or mixed-lineage leukemia protein 1BDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
58 N-terminal cleavage product of 320 kDaBDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
59 Na,K-ATPase α1β1EBI 0 18 0 0 0 0 0 0 0 0 1 3 2D 3DTSV
60 Na,K-ATPase α2β1EBI 0 18 0 0 0 0 0 0 0 0 1 3 2D 3DTSV
61 NACHR alpha-9EBI 0 0 1 0 0 0 0 0 0 0 1 5 2D 3DTSV
62 Neuronal acetylcholine receptor protein alpha-9 subunitEBI 0 0 1 0 0 0 0 0 0 0 1 5 2D 3DTSV
63 Neuronal acetylcholine receptor subunit alpha-9EBI 5 7 4 8 0 0 0 0 0 0 6 7 2D 3DTSV
64 Nicotinic acetylcholine receptor subunit alpha-9EBI 0 0 1 0 0 0 0 0 0 0 1 5 2D 3DTSV
65 p180BDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
66 p320BDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
67 PARP-14BDB 3 0 19 2 0 0 0 0 0 0 3 8 2D 3DTSV
68 PARP14BDB 3 0 19 2 0 0 0 0 0 0 3 8 2D 3DTSV
69 Poly [ADP-ribose] polymerase 14BDB 3 0 19 2 0 0 0 0 0 0 3 8 2D 3DTSV
70 Position-effect variegation 3-9 homologEBI 7 7 14 0 0 0 0 0 0 0 7 6 2D 3DTSV
71 Potassium channel subunit alpha KvLQT2EBI 3 0 0 0 27 0 0 0 0 0 5 14 2D 3DTSV
72 Potassium Channel, Ca2+ Act., VSEBI 2 1 2 0 0 0 0 0 0 0 3 1 2D 3DTSV
73 PPARgamma2 - DNA binding domain of Gal4EBI 0 0 0 0 18 0 0 0 0 0 1 0 2D 3DTSV
74 Reverse transcriptase proteinBDB 0 0 18 0 0 0 0 0 0 0 1 1 2D 3DTSV
75 S-ribosylhomocysteine lyaseEBI 1 34 1 0 0 0 0 0 0 0 3 7 2D 3DTSV
76 SLC16A3EBI 10 0 21 0 0 0 0 0 0 0 1 4 2D 3DTSV
77 Solanesyl diphosphate synthaseEBI 0 0 20 0 0 0 0 0 0 0 2 0 2D 3DTSV
78 Solute carrier family 16 member 3EBI 10 0 21 0 0 0 0 0 0 0 1 4 2D 3DTSV
79 Su(var)3-9 homolog 1EBI 7 7 14 0 0 0 0 0 0 0 7 6 2D 3DTSV
80 Suppressor of variegation 3-9 homolog 1EBI 7 7 14 0 0 0 0 0 0 0 7 6 2D 3DTSV
81 SUV39HEBI 7 7 14 0 0 0 0 0 0 0 7 6 2D 3DTSV
82 SUV39H1EBI 7 7 14 0 0 0 0 0 0 0 7 6 2D 3DTSV
83 Topoisomerase (DNA) II binding protein 1EBI 0 0 0 0 18 0 0 0 0 0 1 5 2D 3DTSV
84 Trithorax-like proteinBDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
85 TRX1BDB 2 1 16 1 0 0 0 0 0 0 8 18 2D 3DTSV
86 UPase 1BDB 3 2 9 27 0 0 0 0 0 0 3 4 2D 3DTSV
87 UrdPase 1BDB 3 2 9 27 0 0 0 0 0 0 3 4 2D 3DTSV
88 Uridine phosphorylase (UPase)BDB 3 2 9 27 0 0 0 0 0 0 3 4 2D 3DTSV
89 Xaa-Pro aminopeptidase 2BDB 1 0 53 0 0 0 0 0 0 0 3 5 2D 3DTSV
90 Zinc finger protein HRXBDB 0 0 6 1 0 0 0 0 0 0 6 12 2D 3DTSV
Sub total293292102713711100000
Total1567