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Targets Binding with 19 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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AffyNet
KiIC50KdEC50koffkonotherITCSDFTSV
1 5'-AMP-activated protein kinase subunit beta-1BDB 7 2 16 0 2 0 0 0 0 0 7 6 2D 3DTSV
2 5'-AMP-activated protein kinase subunit beta-1 (AMPK)BDB 7 2 16 0 2 0 0 0 0 0 7 6 2D 3DTSV
3 5''''''''-AMP-activated protein kinase subunit beta-1BDB 7 2 16 0 2 0 0 0 0 0 7 6 2D 3DTSV
4 5''''-AMP-activated protein kinase catalytic subunit alpha-2/beta-1/gamma-2BDB 7 2 16 0 2 0 0 0 0 0 7 6 2D 3DTSV
5 5''''-AMP-activated protein kinase subunit beta-1BDB 7 2 16 0 2 0 0 0 0 0 7 6 2D 3DTSV
6 5''-AMP-activated protein kinase subunit beta-1BDB 7 2 16 0 2 0 0 0 0 0 7 6 2D 3DTSV
7 72 kDa type IV collagenaseBDB 3 0 19 0 0 0 0 0 0 0 2 4 2D 3DTSV
8 Acidic mammalian chitinase (AMCase)EBI 11 1 19 3 0 0 0 0 0 0 5 10 2D 3DTSV
9 AHFBDB 13 2 33 0 0 0 0 0 0 0 3 4 2D 3DTSV
10 Alpha,alpha-trehalaseEBI 9 1 25 0 0 0 0 0 0 0 6 4 2D 3DTSV
11 AMP-activated protein kinase, beta-1 subunitBDB 7 2 16 0 2 0 0 0 0 0 7 6 2D 3DTSV
12 AMPKBDB 7 2 16 0 2 0 0 0 0 0 7 6 2D 3DTSV
13 AMPK subunit beta-1BDB 7 2 16 0 2 0 0 0 0 0 7 6 2D 3DTSV
14 AMPKbBDB 7 2 16 0 2 0 0 0 0 0 7 6 2D 3DTSV
15 Antihemophilic factorBDB 13 2 33 0 0 0 0 0 0 0 3 4 2D 3DTSV
16 B9Z04_05970EBI 0 0 14 0 0 0 0 0 0 0 1 0 2D 3DTSV
17 B9Z08_04335EBI 0 0 14 0 0 0 0 0 0 0 1 0 2D 3DTSV
18 Beta-lactamase OXA-1BDB 0 2 23 0 0 0 0 0 0 0 4 2 2D 3DTSV
19 Bilirubin-specific UDPGT isozyme 2BDB 0 0 19 0 0 0 0 0 0 0 2 5 2D 3DTSV
20 Biotin ligaseBDB 0 14 6 0 0 0 0 0 0 0 2 1 2D 3DTSV
21 Biotin protein ligase (BPL)BDB 0 25 6 1 0 0 0 0 7 0 6 4 2D 3DTSV
22 BUB1AEBI 1 0 18 1 0 0 0 0 0 0 7 8 2D 3DTSV
23 Cell division protein FtsI (Peptidoglycan synthetase)EBI 0 0 14 0 0 0 0 0 0 0 1 0 2D 3DTSV
24 Class D β-lactamase (OXA-1)BDB 0 2 23 0 0 0 0 0 0 0 4 2 2D 3DTSV
25 Coagulation Factor VIIIBDB 13 2 33 0 0 0 0 0 0 0 3 4 2D 3DTSV
26 Complex III subunit 7EBI 9 0 19 0 0 0 0 0 0 0 1 4 2D 3DTSV
27 Complex III subunit VIIEBI 9 0 19 0 0 0 0 0 0 0 1 4 2D 3DTSV
28 Cysteine-S-conjugate beta-lyaseBDB 5 0 21 0 0 0 0 0 0 0 5 4 2D 3DTSV
29 Cytochrome b-c1 complex subunit 7EBI 9 0 19 0 0 0 0 0 0 0 1 4 2D 3DTSV
30 Cytokinin dehydrogenase 2EBI 4 0 19 0 0 0 0 0 0 0 1 3 2D 3DTSV
31 DENV2 protease (NS2B-NS3)BDB 4 0 20 0 0 0 0 0 0 0 1 13 2D 3DTSV
32 Dephospho-CoA pyrophosphorylaseBDB 0 0 44 0 0 0 0 0 0 0 1 5 2D 3DTSV
33 Dihydrofolate Reductase-Thymidylate Synthase (DHFR-TS) Muatnt (S58R/S117N)BDB 4 19 19 0 0 0 0 0 0 0 1 0 2D 3DTSV
34 Dihydrofolate Reductase-Thymidylate Synthase (DHFR-TS) Mutant SP21BDB 4 19 19 0 0 0 0 0 0 0 1 0 2D 3DTSV
35 Ectonucleoside triphosphate diphosphohydrolase 2EBI 4 21 5 0 0 0 0 0 0 0 5 8 2D 3DTSV
36 EP54_05770EBI 0 0 14 0 0 0 0 0 0 0 1 0 2D 3DTSV
37 EQ90_05620EBI 0 0 14 0 0 0 0 0 0 0 1 0 2D 3DTSV
38 ERS072738_01739EBI 0 0 14 0 0 0 0 0 0 0 1 0 2D 3DTSV
39 Factor VIIIBDB 13 2 33 0 0 0 0 0 0 0 3 4 2D 3DTSV
40 Factor VIII B chainBDB 13 2 33 0 0 0 0 0 0 0 3 4 2D 3DTSV
41 Factor VIIIa heavy chain, 200 kDa isoformBDB 13 2 33 0 0 0 0 0 0 0 3 4 2D 3DTSV
42 Factor VIIIa heavy chain, 92 kDa isoformBDB 13 2 33 0 0 0 0 0 0 0 3 4 2D 3DTSV
43 Factor VIIIa light chainBDB 13 2 33 0 0 0 0 0 0 0 3 4 2D 3DTSV
44 GlcBBDB 0 0 19 0 0 0 0 0 0 0 1 0 2D 3DTSV
45 Glutamine--phenylpyruvate transaminaseBDB 5 0 21 0 0 0 0 0 0 0 5 4 2D 3DTSV
46 hBUB1EBI 1 0 18 1 0 0 0 0 0 0 7 8 2D 3DTSV
47 HIV-1 Protease Mutant M1 (L10I, G48V, I54V, L63P, V82A)BDB 4 19 0 0 0 0 0 0 0 0 2 0 2D 3DTSV
48 HIV-1 Protease Mutant M2 (D30N, L63P, N88D)BDB 4 19 0 0 0 0 0 0 0 0 2 0 2D 3DTSV
49 HIV-1 Protease Mutant M3 (L10I, L63P, A71V, G73S, I84V, L90M)BDB 4 19 0 0 0 0 0 0 0 0 2 0 2D 3DTSV
50 HMPREF3211_00860EBI 0 0 14 0 0 0 0 0 0 0 1 0 2D 3DTSV
51 hUG-BR2BDB 0 0 19 0 0 0 0 0 0 0 2 5 2D 3DTSV
52 Interleukin-6BDB 1 0 19 0 0 0 0 0 0 0 2 5 2D 3DTSV
53 Kynurenine Aminotransferase 1/Glutamine Transaminase KBDB 5 0 21 0 0 0 0 0 0 0 5 4 2D 3DTSV
54 Kynurenine--oxoglutarate transaminase 1BDB 5 0 21 0 0 0 0 0 0 0 5 4 2D 3DTSV
55 likely tRNA 2'-phosphotransferaseBDB 11 0 19 0 0 0 0 0 0 0 1 0 2D 3DTSV
56 Lung-specific protein TSA1902EBI 11 1 19 3 0 0 0 0 0 0 5 10 2D 3DTSV
57 Matrix metalloproteinase-2 (MMP-2)BDB 3 0 19 0 0 0 0 0 0 0 2 4 2D 3DTSV
58 MetacaspaseEBI 0 0 19 0 0 0 0 0 0 0 1 0 2D 3DTSV
59 Mitotic checkpoint serine/threonine-protein kinase BUB1EBI 1 0 18 1 0 0 0 0 0 0 7 8 2D 3DTSV
60 ODCaseBDB 3 13 0 0 0 0 0 0 0 0 4 1 2D 3DTSV
61 OMP decarboxylaseBDB 3 25 0 0 0 0 0 0 0 0 5 1 2D 3DTSV
62 OMPDCaseBDB 3 25 0 0 0 0 0 0 0 0 5 1 2D 3DTSV
63 Orotidine 5-phosphate decarboxylaseBDB 3 27 0 0 0 0 0 0 0 0 5 3 2D 3DTSV
64 p68BDB 0 0 3 0 0 0 0 0 0 0 1 4 2D 3DTSV
65 Pantetheine-phosphate adenylyltransferaseBDB 0 0 44 0 0 0 0 0 0 0 1 5 2D 3DTSV
66 pbp1EBI 0 0 14 0 0 0 0 0 0 0 1 0 2D 3DTSV
67 pbpAEBI 0 0 14 0 0 0 0 0 0 0 1 0 2D 3DTSV
68 Penicillin-binding proteinEBI 0 0 64 0 0 0 0 0 0 0 2 0 2D 3DTSV
69 Penicillin-binding protein 1EBI 0 0 14 0 0 0 0 0 0 0 1 0 2D 3DTSV
70 Penicillin-binding protein 2EBI 0 0 35 0 0 0 0 0 0 0 2 0 2D 3DTSV
71 Phosphatidylcholine:ceramide cholinephosphotransferase 2EBI 6 0 19 0 0 0 0 0 0 0 1 4 2D 3DTSV
72 Phosphodiesterase 6CBDB 7 0 29 0 0 0 0 0 0 0 8 4 2D 3DTSV
73 Phosphodiesterase 6C (PDE6C)BDB 7 0 29 0 0 0 0 0 0 0 8 4 2D 3DTSV
74 Phospholipase D (PLD_SC)BDB 3 0 19 0 0 0 0 0 0 0 1 1 2D 3DTSV
75 Phosphopantetheine adenylyltransferase (PPAT)BDB 0 0 44 0 0 0 0 0 0 0 1 5 2D 3DTSV
76 Potassium-transporting ATPase alpha chain 2EBI 2 0 19 0 0 0 0 0 0 0 4 7 2D 3DTSV
77 PRKAB1BDB 7 2 16 0 2 0 0 0 0 0 7 6 2D 3DTSV
78 Procoagulant componentBDB 13 2 33 0 0 0 0 0 0 0 3 4 2D 3DTSV
79 Protein tyrosine phosphatase type IVA 1EBI 13 0 20 0 0 0 0 0 0 0 4 5 2D 3DTSV
80 Putative penicillin-binding protein 2BEBI 0 0 14 0 0 0 0 0 0 0 1 0 2D 3DTSV
81 PvDHFR-TSBDB 4 18 19 0 0 0 0 0 0 0 1 3 2D 3DTSV
82 QP-CEBI 9 0 19 0 0 0 0 0 0 0 1 4 2D 3DTSV
83 Ribosomal S6 kinase 2 (RSK-2)(C436V)BDB 0 0 19 0 0 0 0 0 0 0 1 0 2D 3DTSV
84 RNA-directed RNA polymerase, C-terminally truncated form delta C21BDB 1 0 20 0 1 0 0 0 0 0 1 3 2D 3DTSV
85 Sentrin-specific protease 2 (SENP2)EBI 1 0 30 0 0 0 0 0 0 0 3 6 2D 3DTSV
86 SGMS2EBI 6 0 19 0 0 0 0 0 0 0 1 4 2D 3DTSV
87 Small conductance calcium-activated potassium channelBDB 2 1 17 0 1 0 0 0 0 0 7 4 2D 3DTSV
88 SMS2EBI 6 0 19 0 0 0 0 0 0 0 1 4 2D 3DTSV
89 Sphingomyelin synthase 2EBI 6 0 19 0 0 0 0 0 0 0 1 4 2D 3DTSV
90 Syk proteinEBI 0 0 19 0 0 0 0 0 0 0 1 0 2D 3DTSV
91 Synonyms=ftsI_2EBI 0 0 14 0 0 0 0 0 0 0 1 0 2D 3DTSV
92 TIMBDB 1 8 16 0 0 0 0 0 0 0 6 10 2D 3DTSV
93 TrehalaseEBI 9 1 25 0 0 0 0 0 0 0 6 4 2D 3DTSV
94 Triose-phosphate isomeraseBDB 1 8 16 0 0 0 0 0 0 0 6 10 2D 3DTSV
95 Triosephosphate isomerase, glycosomalEBI 1 0 9 0 0 0 0 0 0 0 2 1 2D 3DTSV
96 Ubiquinol-cytochrome c reductase complex 14 kDa proteinEBI 9 0 19 0 0 0 0 0 0 0 1 4 2D 3DTSV
97 UDP-glucuronosyltransferase 1-4BDB 0 0 19 0 0 0 0 0 0 0 2 5 2D 3DTSV
98 UDP-glucuronosyltransferase 1-DBDB 0 0 19 0 0 0 0 0 0 0 2 5 2D 3DTSV
99 UDP-glucuronosyltransferase 1A4BDB 0 0 19 0 0 0 0 0 0 0 2 5 2D 3DTSV
100 UDPGT 1-4BDB 0 0 19 0 0 0 0 0 0 0 2 5 2D 3DTSV
101 UGT-1DBDB 0 0 19 0 0 0 0 0 0 0 2 5 2D 3DTSV
102 UGT1*4BDB 0 0 19 0 0 0 0 0 0 0 2 5 2D 3DTSV
103 UGT1-04BDB 0 0 19 0 0 0 0 0 0 0 2 5 2D 3DTSV
104 UGT1.4BDB 0 0 19 0 0 0 0 0 0 0 2 5 2D 3DTSV
105 UGT1A4BDB 0 0 19 0 0 0 0 0 0 0 2 5 2D 3DTSV
106 UGT1DBDB 0 0 19 0 0 0 0 0 0 0 2 5 2D 3DTSV
107 unnamed protein productBDB 11 0 19 0 0 0 0 0 0 0 1 3 2D 3DTSV
108 UQBPEBI 9 0 19 0 0 0 0 0 0 0 1 4 2D 3DTSV
109 UQCRBEBI 9 0 19 0 0 0 0 0 0 0 1 4 2D 3DTSV
110 Uridine-5'-diphosphoglucuronosyltransferase 1A4BDB 0 0 19 0 0 0 0 0 0 0 2 5 2D 3DTSV
111 Uridine-5'-diphosphoglucuronosyltransferase 2B10BDB 0 0 19 0 0 0 0 0 0 0 1 5 2D 3DTSV
Sub total4603282130102400070
Total2492