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Targets Binding with 2011 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

Articles
UniProtKB/
Swiss-Prot/TrEMBL
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KiIC50KdEC50koffkonotherITCSDFTSV
1 bace2BDB 0 1304 843 0 0 0 0 0 0 0 87 9 2D 3DTSV
2 Beta-secretase 2BDB 0 1304 861 0 0 0 0 0 0 0 89 11 2D 3DTSV
3 Beta-site amyloid precursor protein cleaving enzyme 2EBI 0 0 15 0 0 0 0 0 0 0 2 3 2D 3DTSV
4 Beta-site APP cleaving enzyme 2EBI 0 0 15 0 0 0 0 0 0 0 2 3 2D 3DTSV
5 Memapsin-1BDB 0 1304 858 0 0 0 0 0 0 0 88 11 2D 3DTSV
6 Membrane-associated aspartic protease 1BDB 0 1304 858 0 0 0 0 0 0 0 88 11 2D 3DTSV
7 Theta-secretaseEBI 0 0 15 0 0 0 0 0 0 0 2 3 2D 3DTSV
Sub total0521634650000000
Total8681