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Targets Binding with 213 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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KiIC50KdEC50koffkonotherITCSDFTSV
1 CDK2/Cyclin E/G1/S-specific cyclin E2EBI 12 6 215 0 0 0 0 0 0 0 14 0 2D 3DTSV
2 Cyclin-dependent kinase 2/cyclin EEBI 12 6 215 0 0 0 0 0 0 0 14 0 2D 3DTSV
3 Cyclin-dependent kinase 2/G1/S-specific cyclin E1 /G1/S-specific cyclin E2EBI 12 6 215 0 0 0 0 0 0 0 14 0 2D 3DTSV
4 Epidermal growth factor receptor (EGFR) T790MBDB 0 0 219 0 0 0 0 0 0 0 10 0 2D 3DTSV
5 Epidermal growth factor receptor (EGFR)(T790)BDB 0 0 219 0 0 0 0 0 0 0 10 0 2D 3DTSV
6 Epidermal growth factor receptor (EGFR)(T790M)BDB 0 0 219 0 0 0 0 0 0 0 10 0 2D 3DTSV
7 Epidermal growth factor receptor (T790M)BDB 0 0 219 0 0 0 0 0 0 0 10 0 2D 3DTSV
8 Serine protease 31EBI 1 1 9 3 0 0 0 0 0 0 5 6 2D 3DTSV
9 Transmembrane tryptaseEBI 1 1 9 3 0 0 0 0 0 0 5 6 2D 3DTSV
10 Tryptase gammaEBI 1 1 9 3 0 0 0 0 0 0 5 6 2D 3DTSV
11 Tryptase gamma heavy chainEBI 1 1 9 3 0 0 0 0 0 0 5 6 2D 3DTSV
12 Tryptase gamma light chainEBI 1 1 9 3 0 0 0 0 0 0 5 6 2D 3DTSV
Sub total4123156615000000
Total1604