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Targets Binding with 24 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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AffyNet
KiIC50KdEC50koffkonotherITCSDFTSV
1 (ARTD7 or PARP15)BDB 4 0 32 0 0 0 0 0 0 0 3 4 2D 3DTSV
2 (ARTD7 or PARP15, Y598L)BDB 4 0 32 0 0 0 0 0 0 0 3 4 2D 3DTSV
3 4.1.2.27EBI 0 1 0 0 0 0 0 0 0 0 1 1 2D 3DTSV
4 4.2.99.-EBI 0 0 4 0 0 0 0 0 0 0 1 3 2D 3DTSV
5 ADP-ribosyltransferase diphtheria toxin-like 7BDB 4 0 32 0 0 0 0 0 0 0 3 4 2D 3DTSV
6 Advanced glycosylation end product-specific receptorEBI 0 0 24 2 0 0 0 0 0 0 3 17 2D 3DTSV
7 AGEREBI 0 0 24 2 0 0 0 0 0 0 3 17 2D 3DTSV
8 ARTD7BDB 4 0 32 0 0 0 0 0 0 0 3 4 2D 3DTSV
9 B-aggressive lymphoma protein 3BDB 4 0 32 0 0 0 0 0 0 0 3 4 2D 3DTSV
10 BAL3BDB 4 0 32 0 0 0 0 0 0 0 3 4 2D 3DTSV
11 Cereolysin AEBI 0 4 24 0 0 0 0 0 0 0 1 1 2D 3DTSV
12 Cyclin-dependent kinase 2-associated protein 1EBI 0 0 24 0 0 0 0 0 0 0 1 3 2D 3DTSV
13 CYP26A2 EBI 0 0 24 0 0 0 0 0 0 0 1 10 2D 3DTSV
14 CYP26B1EBI 0 0 24 0 0 0 0 0 0 0 1 10 2D 3DTSV
15 CYPIIC18EBI 1 0 24 0 0 0 0 0 0 0 1 7 2D 3DTSV
16 Cytochrome P450 26A2EBI 0 0 24 0 0 0 0 0 0 0 1 10 2D 3DTSV
17 Cytochrome P450 26B1EBI 0 0 24 0 0 0 0 0 0 0 1 10 2D 3DTSV
18 Cytochrome P450 2C18EBI 1 0 24 0 0 0 0 0 0 0 1 7 2D 3DTSV
19 Cytochrome P450 retinoic acid-inactivating 2EBI 0 0 24 0 0 0 0 0 0 0 1 10 2D 3DTSV
20 Cytochrome P450RAI-2EBI 0 0 24 0 0 0 0 0 0 0 1 10 2D 3DTSV
21 DNA topoisomerase II betaEBI 2 0 1 0 23 0 0 0 0 0 2 5 2D 3DTSV
22 FABPIBDB 19 18 5 6 0 0 0 0 6 0 4 3 2D 3DTSV
23 Fatty acid binding protein intestinalBDB 19 18 5 6 0 0 0 0 6 0 4 3 2D 3DTSV
24 Fatty acid-binding protein, intestinalBDB 19 18 5 6 0 0 0 0 6 0 4 3 2D 3DTSV
25 G21EBI 4 19 22 0 0 0 0 0 0 0 6 6 2D 3DTSV
26 GABA A alpha5EBI 9 36 3 0 1 0 0 0 0 0 8 1 2D 3DTSV
27 GABA A Alpha5Beta2Gamma2EBI 9 36 3 0 1 0 0 0 0 0 8 1 2D 3DTSV
28 GABA A Alpha5m10Beta2Gamma2EBI 9 36 3 0 1 0 0 0 0 0 8 1 2D 3DTSV
29 GABA A Alpha5m8Beta2Gamma2EBI 9 36 3 0 1 0 0 0 0 0 8 1 2D 3DTSV
30 GABA A Alpha5m9Beta2Gamma2EBI 9 36 3 0 1 0 0 0 0 0 8 1 2D 3DTSV
31 Glutamate delta 2EBI 13 25 0 0 0 0 0 0 0 0 1 1 2D 3DTSV
32 Glutamate receptor delta-2 subunitEBI 13 25 0 0 0 0 0 0 0 0 1 1 2D 3DTSV
33 Glycogen Synthase Kinase 3 (GSK3)BDB 8 0 24 0 0 0 0 0 0 0 1 1 2D 3DTSV
34 HemagglutininBDB 0 0 22 5 0 0 0 0 0 0 3 9 2D 3DTSV
35 Hemagglutinin HA1 chainBDB 0 0 19 0 0 0 0 0 0 0 2 4 2D 3DTSV
36 Hemagglutinin HA2 chainEBI 0 0 3 0 0 0 0 0 0 0 1 4 2D 3DTSV
37 Heme carrier protein 1EBI 4 19 22 0 0 0 0 0 0 0 6 6 2D 3DTSV
38 Histidinol dehydrogenaseEBI 1 4 42 0 0 0 0 0 0 0 3 4 2D 3DTSV
39 hTrp-3EBI 2 0 25 0 1 0 0 0 0 0 2 8 2D 3DTSV
40 hTrp3EBI 2 0 25 0 1 0 0 0 0 0 2 8 2D 3DTSV
41 Human diphtheria toxin-like ADP-ribosyltransferase (ARTD7 or PARP15)BDB 4 0 33 0 0 0 0 0 0 0 4 4 2D 3DTSV
42 Human diphtheria toxin-like ADP-ribosyltransferase (ARTD7 or PARP15, Y598L)BDB 4 0 32 0 0 0 0 0 0 0 3 4 2D 3DTSV
43 I-FABPBDB 19 18 5 6 0 0 0 0 6 0 4 3 2D 3DTSV
44 IDO-2EBI 12 12 35 0 0 0 0 0 0 0 3 7 2D 3DTSV
45 Ido2EBI 11 0 12 0 0 0 0 0 0 0 1 4 2D 3DTSV
46 Indol1EBI 11 0 12 0 0 0 0 0 0 0 1 4 2D 3DTSV
47 Indoleamine 2,3-dioxygenase 2EBI 12 12 35 0 0 0 0 0 0 0 3 7 2D 3DTSV
48 Indoleamine 2,3-dioxygenase-like protein 1EBI 12 12 35 0 0 0 0 0 0 0 3 7 2D 3DTSV
49 Indoleamine-pyrrole 2,3-dioxygenase-like protein 1EBI 12 12 35 0 0 0 0 0 0 0 3 7 2D 3DTSV
50 Inorganic pyrophosphataseBDB 0 0 24 0 0 0 0 0 0 0 2 5 2D 3DTSV
51 Inorganic pyrophosphatase (MtPPiase)BDB 0 0 24 0 0 0 0 0 0 0 2 5 2D 3DTSV
52 Inositol 1,4,5-trisphosphate 3-kinase (IP3K )BDB 1 1 24 0 0 0 0 0 0 0 1 3 2D 3DTSV
53 Inositol-trisphosphate 3-kinaseBDB 1 1 24 0 0 0 0 0 0 0 1 3 2D 3DTSV
54 Intestinal fatty acid-binding protein (hIFABP)BDB 19 18 5 6 0 0 0 0 6 0 4 3 2D 3DTSV
55 Ionotropic glutamate receptor NMDA 1/2CEBI 0 0 22 0 2 0 0 0 0 0 3 4 2D 3DTSV
56 Kynurenine/alpha-aminoadipate aminotransferaseEBI 4 0 25 0 0 0 0 0 0 0 3 1 2D 3DTSV
57 Medulla oblongata-derived proteinEBI 2 0 24 0 0 0 0 0 0 0 1 0 2D 3DTSV
58 MOB EBI 2 0 24 0 0 0 0 0 0 0 1 0 2D 3DTSV
59 Nitric oxide synthase (bsNOS)BDB 0 0 0 24 0 0 0 0 0 0 1 1 2D 3DTSV
60 P450-6B/29CEBI 1 0 24 0 0 0 0 0 0 0 1 7 2D 3DTSV
61 P450RAI2EBI 0 0 24 0 0 0 0 0 0 0 1 10 2D 3DTSV
62 PARP-15BDB 4 0 32 0 0 0 0 0 0 0 3 4 2D 3DTSV
63 PARP15BDB 4 0 32 0 0 0 0 0 0 0 3 4 2D 3DTSV
64 PCFT/HCP1EBI 4 19 22 0 0 0 0 0 0 0 6 6 2D 3DTSV
65 Phosphatidylcholine 2-acylhydrolase-like protein GIICEBI 0 0 24 0 0 0 0 0 0 0 1 3 2D 3DTSV
66 Phosphatidylcholine cholinephosphohydrolaseEBI 0 4 24 0 0 0 0 0 0 0 1 1 2D 3DTSV
67 Phosphatidylcholine:ceramide cholinephosphotransferase 1EBI 2 0 24 0 0 0 0 0 0 0 1 0 2D 3DTSV
68 Phospholipase A2 group IICEBI 0 0 24 0 0 0 0 0 0 0 1 3 2D 3DTSV
69 Phospholipase CEBI 0 4 24 0 0 0 0 0 0 0 1 1 2D 3DTSV
70 PLCEBI 0 4 24 0 0 0 0 0 0 0 1 1 2D 3DTSV
71 Pol LambdaEBI 0 0 4 0 0 0 0 0 0 0 1 3 2D 3DTSV
72 PolkEBI 0 0 4 0 0 0 0 0 0 0 1 3 2D 3DTSV
73 PollEBI 0 0 4 0 0 0 0 0 0 0 1 3 2D 3DTSV
74 Poly [ADP-ribose] polymerase 15BDB 4 0 32 0 0 0 0 0 0 0 3 4 2D 3DTSV
75 ppaBDB 0 0 24 0 0 0 0 0 0 0 2 5 2D 3DTSV
76 PPaseBDB 0 0 24 0 0 0 0 0 0 0 2 5 2D 3DTSV
77 Procollagen-proline,2-oxoglutarate-4-dioxygenaseBDB 21 22 0 0 0 0 0 0 0 0 1 1 2D 3DTSV
78 Prolyl 4-hydroxylase subunit alpha-1BDB 23 25 3 0 0 0 0 0 0 0 2 7 2D 3DTSV
79 Protein MobEBI 2 0 24 0 0 0 0 0 0 0 1 0 2D 3DTSV
80 Proton-coupled folate transporterEBI 4 19 22 0 0 0 0 0 0 0 6 6 2D 3DTSV
81 Putative inactive group IIC secretory phospholipase A2EBI 0 0 24 0 0 0 0 0 0 0 1 3 2D 3DTSV
82 Pyrophosphate phospho-hydrolaseBDB 0 0 24 0 0 0 0 0 0 0 2 5 2D 3DTSV
83 RAGEEBI 0 0 24 2 0 0 0 0 0 0 3 17 2D 3DTSV
84 Receptor for advanced glycosylation end productsEBI 0 0 24 2 0 0 0 0 0 0 3 17 2D 3DTSV
85 Receptor-type tyrosine-protein kinase FLT3 (D835H)BDB 22 0 0 24 0 0 0 0 0 0 2 0 2D 3DTSV
86 Receptor-type tyrosine-protein kinase FLT3 (D835Y)BDB 19 0 0 22 0 0 0 0 0 0 2 0 2D 3DTSV
87 Retinoic acid-metabolizing cytochromeEBI 0 0 24 0 0 0 0 0 0 0 1 10 2D 3DTSV
88 S1PLEBI 2 1 24 0 0 0 0 0 0 0 2 7 2D 3DTSV
89 Serine/threonine protein phosphatase PP1-gamma catalytic subunitEBI 6 10 42 0 0 0 0 0 0 0 4 1 2D 3DTSV
90 SGMS1EBI 2 0 24 0 0 0 0 0 0 0 1 0 2D 3DTSV
91 SGPL1EBI 2 0 24 0 0 0 0 0 0 0 2 6 2D 3DTSV
92 Short transient receptor potential channel 3EBI 2 0 25 0 1 0 0 0 0 0 2 8 2D 3DTSV
93 SMS1EBI 2 0 24 0 0 0 0 0 0 0 1 0 2D 3DTSV
94 Solute carrier family 46 member 1EBI 4 19 22 0 0 0 0 0 0 0 6 6 2D 3DTSV
95 SP-lyase 1EBI 2 1 24 0 0 0 0 0 0 0 2 7 2D 3DTSV
96 Sphingomyelin synthase 1EBI 2 0 24 0 0 0 0 0 0 0 1 0 2D 3DTSV
97 Sphingosine-1-phosphate aldolaseEBI 2 1 24 0 0 0 0 0 0 0 2 7 2D 3DTSV
98 Sphingosine-1-phosphate lyase 1EBI 2 1 25 0 0 0 0 0 0 0 3 10 2D 3DTSV
99 SPLEBI 0 1 0 0 0 0 0 0 0 0 1 1 2D 3DTSV
100 SPL 1EBI 2 1 24 0 0 0 0 0 0 0 2 7 2D 3DTSV
101 Threonine--tRNA ligaseEBI 0 24 0 0 0 0 0 0 0 0 1 3 2D 3DTSV
102 ThrRSEBI 0 24 0 0 0 0 0 0 0 0 1 3 2D 3DTSV
103 thrSEBI 0 24 0 0 0 0 0 0 0 0 1 3 2D 3DTSV
104 TMEM23EBI 2 0 24 0 0 0 0 0 0 0 1 0 2D 3DTSV
105 Transient receptor protein 3EBI 2 0 25 0 1 0 0 0 0 0 2 8 2D 3DTSV
106 Transmembrane protein 23EBI 2 0 24 0 0 0 0 0 0 0 1 0 2D 3DTSV
107 TRP-3EBI 2 0 25 0 1 0 0 0 0 0 2 8 2D 3DTSV
108 TRP3EBI 2 0 25 0 1 0 0 0 0 0 2 8 2D 3DTSV
109 TrpC3EBI 2 0 25 0 1 0 0 0 0 0 2 8 2D 3DTSV
110 Tubulin--tyrosine ligaseEBI 4 6 0 18 0 0 0 0 0 0 2 5 2D 3DTSV
111 Tyrosine Kinase FLT3 Mutant (D835H)BDB 22 0 0 24 0 0 0 0 0 0 2 0 2D 3DTSV
112 Tyrosine Kinase FLT3 Mutant (D835Y)BDB 19 0 0 22 0 0 0 0 0 0 2 0 2D 3DTSV
113 Tyrosyl-tRNA synthetaseEBI 1 1 27 0 0 0 0 0 0 0 6 6 2D 3DTSV
114 Ubiquitin C-terminal Hydrolase L3 (UCH-L3)BDB 13 1 21 0 0 0 0 2 0 0 3 5 2D 3DTSV
115 y1903EBI 0 24 0 0 0 0 0 0 0 0 1 3 2D 3DTSV
116 YP_2221EBI 0 24 0 0 0 0 0 0 0 0 1 3 2D 3DTSV
Sub total514677219017737002300
Total3083