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Targets Binding with 247 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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KiIC50KdEC50koffkonotherITCSDFTSV
1 2-aminoadipate aminotransferaseBDB 5 13 289 0 0 0 0 0 0 0 7 5 2D 3DTSV
2 2-aminoadipate transaminaseBDB 5 13 289 0 0 0 0 0 0 0 7 5 2D 3DTSV
3 AADATBDB 5 13 289 0 0 0 0 0 0 0 7 5 2D 3DTSV
4 Alpha-aminoadipate aminotransferaseBDB 5 13 289 0 0 0 0 0 0 0 7 5 2D 3DTSV
5 Apurinic-apyrimidinic endonuclease 1 (APE-1)BDB 51 27 252 4 0 0 0 8 0 0 11 5 2D 3DTSV
6 Apurinic/apyrimidinic endonuclease 1 (APE1)BDB 51 27 252 4 0 0 0 8 0 0 11 5 2D 3DTSV
7 BDNF/NT-3 growth factors receptorBDB 88 10 323 132 2 0 0 0 0 0 51 10 2D 3DTSV
8 BDNF/NT-3 growth factors receptor (TRKB)BDB 88 10 323 132 2 0 0 0 0 0 51 10 2D 3DTSV
9 Casein kinase I isoform alphaBDB 94 10 162 80 0 0 0 0 0 0 45 17 2D 3DTSV
10 CK1BDB 95 10 170 80 0 0 0 0 0 0 47 19 2D 3DTSV
11 CKI-alphaBDB 95 10 170 80 0 0 0 0 0 0 47 19 2D 3DTSV
12 CSNK1A1BDB 89 10 91 80 0 0 0 0 0 0 41 16 2D 3DTSV
13 DNA-(apurinic or apyrimidinic site) lyaseBDB 51 27 252 4 0 0 0 8 0 0 11 5 2D 3DTSV
14 Envelope-associated 22 kDa proteinBDB 0 0 1 0 253 0 0 0 0 0 5 3 2D 3DTSV
15 GP145-TrkBBDB 88 10 323 132 2 0 0 0 0 0 51 10 2D 3DTSV
16 KAT/AadATBDB 5 13 289 0 0 0 0 0 0 0 7 5 2D 3DTSV
17 KAT2BDB 5 13 289 0 0 0 0 0 0 0 7 5 2D 3DTSV
18 Kynurenine aminotransferase IIBDB 5 13 289 0 0 0 0 0 0 0 7 5 2D 3DTSV
19 Kynurenine aminotransferase II (KAT II)BDB 5 13 289 0 0 0 0 0 0 0 7 5 2D 3DTSV
20 Kynurenine--oxoglutarate aminotransferase IIBDB 5 13 289 0 0 0 0 0 0 0 7 5 2D 3DTSV
21 Kynurenine--oxoglutarate transaminase 2BDB 5 13 289 0 0 0 0 0 0 0 7 5 2D 3DTSV
22 Kynurenine--oxoglutarate transaminase IIBDB 5 13 289 0 0 0 0 0 0 0 7 5 2D 3DTSV
23 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrialBDB 5 13 289 0 0 0 0 0 0 0 7 5 2D 3DTSV
24 M2-1BDB 0 0 1 0 253 0 0 0 0 0 5 3 2D 3DTSV
25 Matrix M2-1BDB 0 0 1 0 253 0 0 0 0 0 5 3 2D 3DTSV
26 Melanin-concentrating hormone receptor 1 (MCHR1)(E4Q)(A5T)BDB 0 247 0 0 0 0 0 0 0 0 1 0 2D 3DTSV
27 Neurotrophic tyrosine kinase receptor type 2BDB 88 10 323 132 2 0 0 0 0 0 51 10 2D 3DTSV
28 NTRK2BDB 88 10 323 132 2 0 0 0 0 0 51 10 2D 3DTSV
29 nuclear receptor subfamily 0 group B member 1EBI 168 0 249 0 0 0 0 0 0 0 1 4 2D 3DTSV
30 sentrin-specific protease 1EBI 98 0 443 0 0 0 0 0 0 0 11 4 2D 3DTSV
31 Sentrin-specific protease 1 (SENP1)EBI 98 0 443 0 0 0 0 0 0 0 11 4 2D 3DTSV
32 Trk-BBDB 88 10 323 132 2 0 0 0 0 0 51 10 2D 3DTSV
33 TRKBBDB 88 10 323 132 2 0 0 0 0 0 51 10 2D 3DTSV
34 TrkB tyrosine kinaseBDB 88 10 323 132 2 0 0 0 0 0 51 10 2D 3DTSV
35 Tropomyosin-related kinase BBDB 88 10 323 132 2 0 0 0 0 0 51 10 2D 3DTSV
36 Tropomyosin-related kinase B (TRKB)BDB 88 10 323 132 2 0 0 0 0 0 51 10 2D 3DTSV
37 Tyrosine kinase receptor B (Trk-B)BDB 88 10 323 132 2 0 0 0 0 0 51 10 2D 3DTSV
Sub total191863495081784781002400
Total12731