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Targets Binding with 28 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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AffyNet
KiIC50KdEC50koffkonotherITCSDFTSV
1 72 kDa ICln-binding proteinBDB 0 1 28 0 0 0 0 0 0 0 9 11 2D 3DTSV
2 Bromodomain-containing protein 2 Bromo 1 domain(BRD2 BD1)BDB 0 27 0 4 0 0 0 0 0 0 1 0 2D 3DTSV
3 Bromodomain-containing protein 3 Bromo 1 domain(BRD3 BD1)BDB 0 27 0 4 0 0 0 0 0 0 1 0 2D 3DTSV
4 CAH2EBI 8 28 0 0 0 0 0 0 0 0 1 0 2D 3DTSV
5 Carbonic anhydrase 2, isoform AEBI 8 28 0 0 0 0 0 0 0 0 1 0 2D 3DTSV
6 CDK-interacting protein 1EBI 10 0 56 0 0 0 0 0 0 0 1 5 2D 3DTSV
7 Chain B, Rna Aptamer Complexed With Hiv-1 Rev Peptide, Nmr, 7 StructuresBDB 18 0 28 0 0 0 0 0 0 0 1 0 2D 3DTSV
8 Dihydrodipicolinate synthaseEBI 17 12 18 0 0 0 0 0 0 0 3 5 2D 3DTSV
9 Dmel_CG6906EBI 8 28 0 0 0 0 0 0 0 0 1 0 2D 3DTSV
10 Flavin-containing amine oxidase domain-containing protein 1EBI 1 1 28 0 0 0 0 0 0 0 5 9 2D 3DTSV
11 G protein-coupled receptor GPR35EBI 4 0 0 0 28 0 0 0 0 0 1 0 2D 3DTSV
12 Glucose-6-phosphataseEBI 4 0 28 0 0 0 0 0 0 0 4 7 2D 3DTSV
13 Histone demethylase UTXBDB 3 0 27 1 0 0 0 0 0 0 6 4 2D 3DTSV
14 Histone-arginine N-methyltransferase PRMT5BDB 0 1 28 0 0 0 0 0 0 0 9 11 2D 3DTSV
15 hPanK3EBI 14 0 25 0 4 0 0 0 0 0 1 5 2D 3DTSV
16 HRMT1L5BDB 0 1 28 0 0 0 0 0 0 0 9 11 2D 3DTSV
17 IBP72BDB 0 1 28 0 0 0 0 0 0 0 9 11 2D 3DTSV
18 Integrin alpha2beta1BDB 0 0 33 0 0 0 0 0 0 0 1 1 2D 3DTSV
19 Jak-binding protein 1BDB 0 1 28 0 0 0 0 0 0 0 9 11 2D 3DTSV
20 JBP1BDB 0 1 28 0 0 0 0 0 0 0 9 11 2D 3DTSV
21 KDM6ABDB 3 0 27 1 0 0 0 0 0 0 6 4 2D 3DTSV
22 LD26647pEBI 8 28 0 0 0 0 0 0 0 0 1 0 2D 3DTSV
23 Lysine-specific demethylase 6ABDB 3 0 27 1 0 0 0 0 0 0 6 4 2D 3DTSV
24 Lysine-specific demethylase 6A (KDM6A(UTX))BDB 3 0 27 1 0 0 0 0 0 0 6 4 2D 3DTSV
25 Lysine-specific demethylase 6A (KDM6A)BDB 3 0 27 1 0 0 0 0 0 0 6 4 2D 3DTSV
26 Lysine-specific histone demethylase 1BEBI 1 1 28 0 0 0 0 0 0 0 5 9 2D 3DTSV
27 Lysine-specific histone demethylase 2EBI 1 1 28 0 0 0 0 0 0 0 5 9 2D 3DTSV
28 MEBI 1 0 11 0 0 0 0 0 0 0 1 5 2D 3DTSV
29 Matrix protein 2EBI 1 0 34 0 0 0 0 0 0 0 4 5 2D 3DTSV
30 Non-structural protein 5A (NS5A)(Y93H)BDB 0 0 0 0 42 0 0 0 0 0 2 0 2D 3DTSV
31 NR2B Channel BlockerEBI 5 18 17 0 14 0 0 0 0 0 4 1 2D 3DTSV
32 PANK3EBI 14 0 25 0 4 0 0 0 0 0 1 5 2D 3DTSV
33 Pantothenate kinase 3EBI 14 0 25 0 4 0 0 0 0 0 1 5 2D 3DTSV
34 Pantothenic acid kinase 3EBI 14 0 25 0 4 0 0 0 0 0 1 5 2D 3DTSV
35 Phosphatidylinositol 4-kinase type 2-alphaEBI 1 0 29 0 0 0 0 0 0 0 5 4 2D 3DTSV
36 Phosphatidylinositol 4-kinase type II-alphaEBI 1 0 29 0 0 0 0 0 0 0 5 4 2D 3DTSV
37 PI4K2AEBI 1 0 29 0 0 0 0 0 0 0 5 4 2D 3DTSV
38 Plasmepsin VEBI 1 0 29 0 0 0 0 0 0 0 1 0 2D 3DTSV
39 PRMT5BDB 0 1 28 0 0 0 0 0 0 0 9 11 2D 3DTSV
40 Protein arginine methyltransferase 5 (PRMT5)BDB 0 1 28 0 0 0 0 0 0 0 9 11 2D 3DTSV
41 Protein arginine N-methyltransferase 5BDB 0 1 28 0 0 0 0 0 0 0 9 11 2D 3DTSV
42 Protein arginine N-methyltransferase 5 (PRMT5)BDB 0 1 28 0 0 0 0 0 0 0 9 11 2D 3DTSV
43 Proton channel protein M2EBI 1 0 11 0 0 0 0 0 0 0 1 5 2D 3DTSV
44 SARS Coronavirus Coronavirus Papain-Like ProteaseBDB 8 1 26 2 0 0 0 4 0 0 2 0 2D 3DTSV
45 SARS-CoV papain-like protease (SARS-PLpro)BDB 8 1 26 2 0 0 0 4 0 0 2 0 2D 3DTSV
46 SARS-CoV PLproBDB 8 1 26 2 0 0 0 4 0 0 2 0 2D 3DTSV
47 Serine protease NS5A (Y93H)BDB 0 0 0 0 42 0 0 0 0 0 2 0 2D 3DTSV
48 Shk1 kinase-binding protein 1 homologBDB 0 1 28 0 0 0 0 0 0 0 9 11 2D 3DTSV
49 SKB1BDB 0 1 28 0 0 0 0 0 0 0 9 11 2D 3DTSV
50 SKB1 homologBDB 0 1 28 0 0 0 0 0 0 0 9 11 2D 3DTSV
51 SKB1HsBDB 0 1 28 0 0 0 0 0 0 0 9 11 2D 3DTSV
52 Sterol regulatory element-binding protein 2EBI 13 0 30 0 0 0 0 0 0 0 2 6 2D 3DTSV
53 Thiopurine S-methyltransferaseEBI 24 0 27 1 0 0 0 0 0 0 2 14 2D 3DTSV
54 Ubiquitously-transcribed TPR protein on the X chromosomeBDB 3 0 27 1 0 0 0 0 0 0 6 4 2D 3DTSV
55 Ubiquitously-transcribed X chromosome tetratricopeptide repeat proteinBDB 3 0 27 1 0 0 0 0 0 0 6 4 2D 3DTSV
56 Urea Amidohydrolase Subunit alphaBDB 7 0 29 0 0 0 0 0 0 0 2 1 2D 3DTSV
57 UreCBDB 7 0 29 0 0 0 0 0 0 0 2 1 2D 3DTSV
58 UTXBDB 3 0 27 1 0 0 0 0 0 0 6 4 2D 3DTSV
Sub total255216133723142001200
Total1730