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Targets Binding with 29 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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KiIC50KdEC50koffkonotherITCSDFTSV
1 alternatively spliced Trp4BDB 7 0 29 0 0 0 0 0 0 0 3 6 2D 3DTSV
2 AP3A hydrolaseEBI 0 29 0 0 0 0 0 0 0 0 2 9 2D 3DTSV
3 AP3AaseEBI 0 29 0 0 0 0 0 0 0 0 2 9 2D 3DTSV
4 Aromatic-L-amino-acid decarboxylaseBDB 3 0 30 0 0 0 0 0 0 0 2 10 2D 3DTSV
5 Beta tubulinEBI 2 0 30 0 0 0 0 0 0 0 3 0 2D 3DTSV
6 Beta-glucosidase AEBI 4 8 33 0 0 0 0 0 0 0 7 1 2D 3DTSV
7 Bis(5'adenosyl)-triphosphataseEBI 0 29 0 0 0 0 0 0 0 0 2 9 2D 3DTSV
8 Bromodomain-containing protein 3 Bromo 2 domain(BRD3 BD2)BDB 0 28 0 4 0 0 0 0 0 0 1 0 2D 3DTSV
9 BTG1-binding factor 1EBI 0 0 29 0 0 0 0 0 0 0 1 8 2D 3DTSV
10 CAF-1EBI 0 0 29 0 0 0 0 0 0 0 1 8 2D 3DTSV
11 CAF1EBI 0 0 29 0 0 0 0 0 0 0 1 8 2D 3DTSV
12 Caf1aEBI 0 0 29 0 0 0 0 0 0 0 1 8 2D 3DTSV
13 Casein kinase 1, delta tv1EBI 0 0 29 0 0 0 0 0 0 0 2 2 2D 3DTSV
14 CCNA2EBI 0 0 29 0 0 0 0 0 0 0 1 3 2D 3DTSV
15 CCR4-associated factor 1EBI 0 0 29 0 0 0 0 0 0 0 1 8 2D 3DTSV
16 CCR4-NOT transcription complex subunit 7EBI 0 0 29 0 0 0 0 0 0 0 1 8 2D 3DTSV
17 CDK-interacting protein 1EBI 10 0 57 0 0 0 0 0 0 0 2 6 2D 3DTSV
18 CNOT7EBI 0 0 29 0 0 0 0 0 0 0 1 8 2D 3DTSV
19 Cytochrome P450 14alpha-demethylaseEBI 0 0 0 31 0 0 0 0 0 0 2 1 2D 3DTSV
20 DDCBDB 1 0 15 0 0 0 0 0 0 0 1 1 2D 3DTSV
21 Diadenosine 5',5'''-P1,P3-triphosphate hydrolaseEBI 0 29 0 0 0 0 0 0 0 0 2 9 2D 3DTSV
22 DinucleosidetriphosphataseEBI 0 29 0 0 0 0 0 0 0 0 2 9 2D 3DTSV
23 DOPA decarboxylase (DDC)BDB 1 0 15 0 0 0 0 0 0 0 1 1 2D 3DTSV
24 Dopamine receptor-interacting protein 5EBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
25 DRIP5EBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
26 Envelope glycoprotein E1 and E2BDB 0 0 0 0 30 0 0 0 0 0 1 0 2D 3DTSV
27 Ferrochelatase R115L (FECH)BDB 28 0 0 29 0 0 0 0 0 0 1 0 2D 3DTSV
28 Fragile histidine triad proteinEBI 0 29 0 0 0 0 0 0 0 0 2 9 2D 3DTSV
29 G protein-coupled receptor GPR35EBI 4 0 0 0 29 0 0 0 0 0 2 1 2D 3DTSV
30 GABA A alpha6EBI 19 34 0 0 1 0 0 0 0 0 5 4 2D 3DTSV
31 GABA A Alpha6Beta2Gamma2EBI 19 34 0 0 1 0 0 0 0 0 5 4 2D 3DTSV
32 Glycogen debranching enzymeEBI 21 0 31 0 0 0 0 0 0 0 3 12 2D 3DTSV
33 Guanine nucleotide-binding protein G(i), alpha-1 subunitEBI 0 0 0 0 29 0 0 0 0 0 1 11 2D 3DTSV
34 hRap1EBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
35 Human T-cell leukemia virus type I proteaseEBI 1 4 27 0 0 0 0 0 0 0 2 1 2D 3DTSV
36 Mammalian target of Rapamycin (mTORC1)EBI 1 0 29 0 0 0 0 0 0 0 4 0 2D 3DTSV
37 Matrix metalloproteinase 17EBI 2 0 31 0 0 0 0 0 0 0 5 3 2D 3DTSV
38 Matrix metalloproteinase-17EBI 2 0 31 0 0 0 0 0 0 0 5 3 2D 3DTSV
39 Membrane-type matrix metalloproteinase 4EBI 2 0 31 0 0 0 0 0 0 0 5 3 2D 3DTSV
40 Membrane-type-4 matrix metalloproteinaseEBI 2 0 31 0 0 0 0 0 0 0 5 3 2D 3DTSV
41 MMP-17EBI 2 0 31 0 0 0 0 0 0 0 5 3 2D 3DTSV
42 MT-MMP 4EBI 2 0 31 0 0 0 0 0 0 0 5 3 2D 3DTSV
43 MT4-MMPEBI 2 0 31 0 0 0 0 0 0 0 5 3 2D 3DTSV
44 MT4MMPEBI 2 0 31 0 0 0 0 0 0 0 5 3 2D 3DTSV
45 MTMMP4EBI 2 0 31 0 0 0 0 0 0 0 5 3 2D 3DTSV
46 Neuraminidase (NA)BDB 0 0 30 0 0 0 0 0 0 0 1 1 2D 3DTSV
47 Notch 1-CBF1EBI 0 0 33 0 0 0 0 0 0 0 2 0 2D 3DTSV
48 Notch 3-CBF1EBI 0 0 33 0 0 0 0 0 0 0 2 0 2D 3DTSV
49 Notch1-CBF1EBI 0 0 33 0 0 0 0 0 0 0 2 0 2D 3DTSV
50 Notch3-CBF1EBI 0 0 33 0 0 0 0 0 0 0 2 0 2D 3DTSV
51 Plasmepsin VEBI 1 0 30 0 0 0 0 0 0 0 2 2 2D 3DTSV
52 Prostaglandin-H2 D-isomeraseEBI 7 0 32 0 0 0 0 0 0 0 2 6 2D 3DTSV
53 Protein-tyrosine phosphatase G1BDB 0 0 29 0 0 0 0 0 0 0 6 10 2D 3DTSV
54 PTP-PESTBDB 0 0 29 0 0 0 0 0 0 0 6 10 2D 3DTSV
55 PTPG1BDB 0 0 29 0 0 0 0 0 0 0 6 10 2D 3DTSV
56 RAP1EBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
57 RAP1 homologEBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
58 Receptor-histidine kinase AgrCEBI 0 0 40 6 4 0 0 0 0 0 4 1 2D 3DTSV
59 Repressor/activator protein 1 homologEBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
60 Simian sarcoma virus Pol proteinEBI 0 13 22 0 0 0 0 0 0 0 1 3 2D 3DTSV
61 Telomeric repeat-binding factor 2-interacting protein 1EBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
62 TERF2-interacting telomeric protein 1EBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
63 TERF2IPEBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
64 TRF2-interacting telomeric protein 1EBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
65 Tyrosine-protein phosphatase non-receptor type 12BDB 0 0 29 0 0 0 0 0 0 0 6 10 2D 3DTSV
66 Tyrosine-protein phosphatase non-receptor type 12 (PTP-PEST)BDB 0 0 29 0 0 0 0 0 0 0 6 10 2D 3DTSV
Sub total14753515171109400000
Total2256