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Targets Binding with 29 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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AffyNet
KiIC50KdEC50koffkonotherITCSDFTSV
1 40 kDa peptidyl-prolyl cis-trans isomeraseBDB 1 17 12 18 0 0 0 0 0 0 5 3 2D 3DTSV
2 6-phosphogluconate dehydrogenaseBDB 11 33 19 0 0 0 0 0 0 0 4 5 2D 3DTSV
3 6-phosphogluconate dehydrogenase (6PGD)BDB 11 33 19 0 0 0 0 0 0 0 4 5 2D 3DTSV
4 Acetolactate synthaseEBI 10 1 31 0 0 0 0 0 0 0 3 7 2D 3DTSV
5 ANO1EBI 0 0 29 0 0 0 0 0 0 0 1 5 2D 3DTSV
6 Anoctamin-1EBI 0 0 29 0 0 0 0 0 0 0 1 5 2D 3DTSV
7 ANP-AEBI 0 15 3 0 11 0 0 0 0 0 3 5 2D 3DTSV
8 ANPRAEBI 0 15 3 0 11 0 0 0 0 0 3 5 2D 3DTSV
9 AP3A hydrolaseEBI 0 29 0 0 0 0 0 0 0 0 2 8 2D 3DTSV
10 AP3AaseEBI 0 29 0 0 0 0 0 0 0 0 2 8 2D 3DTSV
11 Aromatic-L-amino-acid decarboxylaseBDB 3 0 30 0 0 0 0 0 0 0 2 8 2D 3DTSV
12 ASCT2 EBI 0 0 32 0 0 0 0 0 0 0 2 12 2D 3DTSV
13 ATB(0)EBI 0 0 32 0 0 0 0 0 0 0 2 12 2D 3DTSV
14 Atrial natriuretic peptide A-type receptorEBI 0 15 3 0 11 0 0 0 0 0 3 5 2D 3DTSV
15 Atrial natriuretic peptide receptor AEBI 0 15 3 0 11 0 0 0 0 0 3 5 2D 3DTSV
16 Baboon M7 virus receptorEBI 0 0 32 0 0 0 0 0 0 0 2 12 2D 3DTSV
17 Beta tubulinEBI 2 0 30 0 0 0 0 0 0 0 3 0 2D 3DTSV
18 Beta-glucosidase AEBI 4 8 33 0 0 0 0 0 0 0 7 1 2D 3DTSV
19 Bis(5'adenosyl)-triphosphataseEBI 0 29 0 0 0 0 0 0 0 0 2 8 2D 3DTSV
20 Bromodomain-containing protein 3 Bromo 2 domain(BRD3 BD2)BDB 0 28 0 4 0 0 0 0 0 0 1 0 2D 3DTSV
21 BTG1-binding factor 1EBI 0 0 29 0 0 0 0 0 0 0 1 8 2D 3DTSV
22 CAF-1EBI 0 0 29 0 0 0 0 0 0 0 1 8 2D 3DTSV
23 CAF1EBI 0 0 29 0 0 0 0 0 0 0 1 8 2D 3DTSV
24 Caf1aEBI 0 0 29 0 0 0 0 0 0 0 1 8 2D 3DTSV
25 Carnitine palmitoyltransferase 1BEBI 5 4 30 0 0 0 0 0 0 0 5 1 2D 3DTSV
26 CCR4-associated factor 1EBI 0 0 29 0 0 0 0 0 0 0 1 8 2D 3DTSV
27 CCR4-NOT transcription complex subunit 7EBI 0 0 29 0 0 0 0 0 0 0 1 8 2D 3DTSV
28 CD87BDB 0 30 0 0 0 0 0 0 0 0 1 5 2D 3DTSV
29 CNOT7EBI 0 0 29 0 0 0 0 0 0 0 1 8 2D 3DTSV
30 Cyclophilin D (CypD)BDB 1 17 12 18 0 0 0 0 0 0 5 3 2D 3DTSV
31 Cyclophilin-40BDB 1 17 12 18 0 0 0 0 0 0 5 3 2D 3DTSV
32 Cyclophilin-related proteinBDB 1 17 12 18 0 0 0 0 0 0 5 3 2D 3DTSV
33 CYP-40BDB 1 17 12 18 0 0 0 0 0 0 5 3 2D 3DTSV
34 DDCBDB 1 0 15 0 0 0 0 0 0 0 1 0 2D 3DTSV
35 Diadenosine 5',5'''-P1,P3-triphosphate hydrolaseEBI 0 29 0 0 0 0 0 0 0 0 2 8 2D 3DTSV
36 DinucleosidetriphosphataseEBI 0 29 0 0 0 0 0 0 0 0 2 8 2D 3DTSV
37 Discovered on gastrointestinal stromal tumors protein 1EBI 0 0 29 0 0 0 0 0 0 0 1 5 2D 3DTSV
38 DOG1EBI 0 0 29 0 0 0 0 0 0 0 1 5 2D 3DTSV
39 DOPA decarboxylase (DDC)BDB 1 0 15 0 0 0 0 0 0 0 1 0 2D 3DTSV
40 Dopamine receptor-interacting protein 5EBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
41 DRIP5EBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
42 Dual specificity mitogen-activated protein kinase kinase; MEK1/2EBI 1 0 35 0 0 0 0 0 0 0 6 2 2D 3DTSV
43 Dual-specificity tyrosine-phosphorylation regulated kinase 3EBI 2 1 31 0 0 0 0 0 0 0 12 6 2D 3DTSV
44 Envelope glycoprotein E1 and E2BDB 0 0 0 0 30 0 0 0 0 0 1 0 2D 3DTSV
45 Ferrochelatase R115L (FECH)BDB 28 0 0 29 0 0 0 0 0 0 1 0 2D 3DTSV
46 Fragile histidine triad proteinEBI 0 29 0 0 0 0 0 0 0 0 2 8 2D 3DTSV
47 GABA A alpha6EBI 19 34 0 0 1 0 0 0 0 0 5 4 2D 3DTSV
48 GABA A Alpha6Beta2Gamma2EBI 19 34 0 0 1 0 0 0 0 0 5 4 2D 3DTSV
49 GC-AEBI 0 15 3 0 11 0 0 0 0 0 3 5 2D 3DTSV
50 Glycogen debranching enzymeEBI 21 0 31 0 0 0 0 0 0 0 3 11 2D 3DTSV
51 Guanine nucleotide-binding protein G(i), alpha-1 subunitEBI 0 0 0 0 29 0 0 0 0 0 1 11 2D 3DTSV
52 Guanylate cyclaseEBI 0 15 3 0 11 0 0 0 0 0 3 5 2D 3DTSV
53 Heme oxygenaseEBI 5 0 0 29 0 0 0 0 0 0 2 0 2D 3DTSV
54 hRap1EBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
55 Human T-cell leukemia virus type I proteaseEBI 1 4 27 0 0 0 0 0 0 0 2 1 2D 3DTSV
56 Iron-starvation protein PigAEBI 5 0 0 29 0 0 0 0 0 0 2 0 2D 3DTSV
57 M7V1EBI 0 0 32 0 0 0 0 0 0 0 2 12 2D 3DTSV
58 Neuraminidase (NA)BDB 0 0 30 0 0 0 0 0 0 0 1 1 2D 3DTSV
59 Neutral amino acid transporter B(0)EBI 0 0 32 0 0 0 0 0 0 0 2 12 2D 3DTSV
60 Notch 1-CBF1EBI 0 0 33 0 0 0 0 0 0 0 2 2 2D 3DTSV
61 Notch 3-CBF1EBI 0 0 33 0 0 0 0 0 0 0 2 2 2D 3DTSV
62 Notch1-CBF1EBI 0 0 33 0 0 0 0 0 0 0 2 2 2D 3DTSV
63 Notch3-CBF1EBI 0 0 33 0 0 0 0 0 0 0 2 2 2D 3DTSV
64 NPR-AEBI 0 15 3 0 11 0 0 0 0 0 3 5 2D 3DTSV
65 Oral cancer overexpressed protein 2EBI 0 0 29 0 0 0 0 0 0 0 1 5 2D 3DTSV
66 ORAOV2EBI 0 0 29 0 0 0 0 0 0 0 1 5 2D 3DTSV
67 p-MEK1/2EBI 1 0 35 0 0 0 0 0 0 0 6 2 2D 3DTSV
68 Peptidyl-prolyl cis-trans isomerase DBDB 1 17 12 18 0 0 0 0 0 0 5 3 2D 3DTSV
69 Phosphodiesterase 9A (PDE9A2)BDB 0 0 35 0 0 0 0 0 0 0 2 0 2D 3DTSV
70 Phosphodiesterase 9A2BDB 0 0 35 0 0 0 0 0 0 0 2 0 2D 3DTSV
71 Plasminogen activator urokinaseBDB 0 30 0 0 0 0 0 0 0 0 1 5 2D 3DTSV
72 PPIase DBDB 1 17 12 18 0 0 0 0 0 0 5 3 2D 3DTSV
73 Prostaglandin-H2 D-isomeraseEBI 7 0 32 0 0 0 0 0 0 0 2 6 2D 3DTSV
74 RAP1EBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
75 RAP1 homologEBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
76 RD114/simian type D retrovirus receptorEBI 0 0 32 0 0 0 0 0 0 0 2 12 2D 3DTSV
77 RDREBI 0 0 32 0 0 0 0 0 0 0 2 12 2D 3DTSV
78 RDRCEBI 0 0 32 0 0 0 0 0 0 0 2 12 2D 3DTSV
79 Repressor/activator protein 1 homologEBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
80 Rotamase DBDB 1 17 12 18 0 0 0 0 0 0 5 3 2D 3DTSV
81 Simian sarcoma virus Pol proteinEBI 0 13 22 0 0 0 0 0 0 0 1 0 2D 3DTSV
82 Slc1a5EBI 0 0 20 0 0 0 0 0 0 0 1 0 2D 3DTSV
83 Sodium-dependent neutral amino acid transporter type 2EBI 0 0 32 0 0 0 0 0 0 0 2 12 2D 3DTSV
84 Solute carrier family 1 member 5EBI 0 0 32 0 0 0 0 0 0 0 2 12 2D 3DTSV
85 TAOS2EBI 0 0 29 0 0 0 0 0 0 0 1 5 2D 3DTSV
86 Telomeric repeat-binding factor 2-interacting protein 1EBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
87 TERF2-interacting telomeric protein 1EBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
88 TERF2IPEBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
89 TMEM16AEBI 0 0 29 0 0 0 0 0 0 0 1 5 2D 3DTSV
90 Transmembrane protein 16AEBI 0 0 29 0 0 0 0 0 0 0 1 5 2D 3DTSV
91 TRF2-interacting telomeric protein 1EBI 0 24 25 4 0 0 0 0 0 0 1 6 2D 3DTSV
92 tRNA synthetase (TyrRS)BDB 0 0 29 0 0 0 0 0 0 0 2 1 2D 3DTSV
93 Tumor-amplified and overexpressed sequence 2EBI 0 0 29 0 0 0 0 0 0 0 1 5 2D 3DTSV
94 Tyrosine--tRNA ligaseBDB 0 0 29 0 0 0 0 0 0 0 2 1 2D 3DTSV
95 Tyrosyl-tRNA synthetase (TryRS)BDB 0 0 29 0 0 0 0 0 0 0 2 1 2D 3DTSV
96 URKRBDB 0 30 0 0 0 0 0 0 0 0 1 5 2D 3DTSV
Sub total165938195427513800000
Total3305