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Targets Binding with 303 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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KiIC50KdEC50koffkonotherITCSDFTSV
1 15-hydroxyprostaglandin dehydrogenase [NAD+]BDB 7 0 377 0 0 0 0 0 0 0 8 10 2D 3DTSV
2 15-PGDHBDB 7 0 379 0 0 0 0 0 0 0 8 14 2D 3DTSV
3 A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)BDB 3 11 310 0 0 0 0 2 0 0 32 7 2D 3DTSV
4 Aggrecanase-1BDB 3 11 310 0 0 0 0 2 0 0 32 7 2D 3DTSV
5 Eif2ak3EBI 0 0 1 0 0 0 0 0 0 0 1 1 2D 3DTSV
6 HpgdBDB 7 0 379 0 0 0 0 0 0 0 8 14 2D 3DTSV
7 Macrophage migration inhibitory factor (MIF)BDB 102 104 339 2 0 0 0 0 0 0 22 9 2D 3DTSV
8 Metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)BDB 3 11 316 0 0 0 0 2 0 0 32 8 2D 3DTSV
9 Pancreatic eIF2-alpha kinaseEBI 0 0 1 0 0 0 0 0 0 0 1 1 2D 3DTSV
10 PekEBI 0 0 1 0 0 0 0 0 0 0 1 1 2D 3DTSV
11 PerkEBI 0 0 1 0 0 0 0 0 0 0 1 1 2D 3DTSV
12 Pgdh1BDB 7 0 379 0 0 0 0 0 0 0 8 14 2D 3DTSV
13 PRKR-like endoplasmic reticulum kinaseEBI 0 0 1 0 0 0 0 0 0 0 1 1 2D 3DTSV
14 Prostaglandin dehydrogenase 1 (15-PGDH)BDB 7 0 379 0 0 0 0 0 0 0 8 14 2D 3DTSV
Sub total14613731732000600
Total3318