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Targets Binding with 31 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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AffyNet
KiIC50KdEC50koffkonotherITCSDFTSV
1 1,4-Dihydroxy-2-naphthoyl-CoA synthaseEBI 7 12 37 0 0 0 0 0 0 0 2 5 2D 3DTSV
2 17-beta-HSD 14EBI 0 32 0 0 0 0 0 0 0 0 2 1 2D 3DTSV
3 17-beta-hydroxysteroid dehydrogenase 14EBI 0 32 0 0 0 0 0 0 0 0 2 1 2D 3DTSV
4 17-beta-hydroxysteroid dehydrogenase DHRS10EBI 0 32 0 0 0 0 0 0 0 0 2 1 2D 3DTSV
5 Activating transcription factor 1EBI 0 0 31 0 0 0 0 0 0 0 1 5 2D 3DTSV
6 ATP-binding cassette sub-family C member 8EBI 1 0 33 5 0 0 0 0 0 0 3 10 2D 3DTSV
7 Branched-chain-amino-acid transferaseEBI 2 0 33 0 0 0 0 0 0 0 4 10 2D 3DTSV
8 Calcium channel (VER)BDB 0 9 30 0 0 0 0 0 0 0 7 6 2D 3DTSV
9 Calcium release-activated calcium channelBDB 0 9 30 0 0 0 0 0 0 0 7 6 2D 3DTSV
10 Calcium release-activated calcium channel protein 1BDB 0 9 30 0 0 0 0 0 0 0 7 6 2D 3DTSV
11 cAMP-dependent transcription factor ATF-1EBI 0 0 31 0 0 0 0 0 0 0 1 5 2D 3DTSV
12 cAMP-specific 3,5-cyclic phosphodiesterase 4BBDB 23 0 31 0 0 0 0 0 0 0 2 0 2D 3DTSV
13 cAMP-specific 3,5-cyclic phosphodiesterase 4DBDB 23 0 31 0 0 0 0 0 0 0 2 0 2D 3DTSV
14 Clan CD, family C13, asparaginyl endopeptidase-like cysteine peptidaseBDB 0 0 30 0 0 0 0 0 0 0 1 1 2D 3DTSV
15 Cyclic AMP-dependent transcription factor ATF-1EBI 0 0 31 0 0 0 0 0 0 0 1 5 2D 3DTSV
16 CyclinEBI 7 0 33 0 0 0 0 0 0 0 2 4 2D 3DTSV
17 Cycloartenol synthaseEBI 2 0 31 0 0 0 0 0 0 0 2 3 2D 3DTSV
18 Dehydrogenase/reductase SDR family member 10EBI 0 32 0 0 0 0 0 0 0 0 2 1 2D 3DTSV
19 DHNA-CoA synthaseEBI 7 12 37 0 0 0 0 0 0 0 2 5 2D 3DTSV
20 DHRS10 EBI 0 32 0 0 0 0 0 0 0 0 2 1 2D 3DTSV
21 Di-trans,poly-cis-decaprenylcistransferaseEBI 0 0 32 0 0 0 0 0 0 0 1 1 2D 3DTSV
22 Dihydrofolate reductase (A16V+S108T)EBI 5 31 0 0 0 0 0 0 0 0 1 0 2D 3DTSV
23 Ditrans,polycis-undecaprenyl-diphosphate synthaseEBI 0 0 32 0 0 0 0 0 0 0 1 1 2D 3DTSV
24 DNA polymerase iotaBDB 6 2 40 0 0 0 0 0 0 0 14 12 2D 3DTSV
25 Estrogen-related receptor, betaEBI 2 0 31 0 2 0 0 0 0 0 3 0 2D 3DTSV
26 Eta2EBI 0 0 4 0 0 0 0 0 0 0 2 5 2D 3DTSV
27 Hexose transporter 1EBI 0 32 0 0 0 0 0 0 0 0 2 0 2D 3DTSV
28 Histone lysine demethylase PHF8BDB 6 0 31 0 0 0 0 0 0 0 7 12 2D 3DTSV
29 Histone lysine demethylase PHF8 (PHF8)BDB 6 0 31 0 0 0 0 0 0 0 7 12 2D 3DTSV
30 HSD17B14EBI 0 32 0 0 0 0 0 0 0 0 2 1 2D 3DTSV
31 IGPDEBI 0 26 29 0 0 0 0 0 0 0 1 5 2D 3DTSV
32 Imidazoleglycerol-phosphate dehydrataseEBI 0 26 29 0 0 0 0 0 0 0 1 5 2D 3DTSV
33 LCGREBI 0 1 1 0 31 0 0 0 0 0 4 5 2D 3DTSV
34 LGR2EBI 0 1 1 0 31 0 0 0 0 0 4 5 2D 3DTSV
35 LHCGREBI 0 1 1 0 31 0 0 0 0 0 4 5 2D 3DTSV
36 LHRHREBI 0 1 1 0 31 0 0 0 0 0 4 5 2D 3DTSV
37 Lysine-specific demethylase 7A/7BBDB 6 0 31 0 0 0 0 0 0 0 7 12 2D 3DTSV
38 Lysine-specific demethylase 7B (KDM7B)BDB 6 0 31 0 0 0 0 0 0 0 7 12 2D 3DTSV
39 M-phase inducer phosphatase 2EBI 0 0 32 0 0 0 0 0 0 0 1 3 2D 3DTSV
40 p53-induced protein phosphatase 1EBI 4 2 31 0 0 0 0 0 0 0 4 5 2D 3DTSV
41 PCNAEBI 7 0 33 0 0 0 0 0 0 0 2 4 2D 3DTSV
42 PH domain leucine-rich repeat-containing protein phosphatase 2EBI 3 0 31 0 0 0 0 0 0 0 1 5 2D 3DTSV
43 PH domain leucine-rich repeat-containing protein phosphatase-likeEBI 3 0 31 0 0 0 0 0 0 0 1 5 2D 3DTSV
44 PHD finger protein 8BDB 6 0 31 0 0 0 0 0 0 0 7 12 2D 3DTSV
45 PHLPP-likeEBI 3 0 31 0 0 0 0 0 0 0 1 5 2D 3DTSV
46 Phosphodiesterase Type 4 (PDE4D)BDB 23 0 31 0 0 0 0 0 0 0 2 0 2D 3DTSV
47 POLIEBI 0 0 4 0 0 0 0 0 0 0 2 5 2D 3DTSV
48 Polycystin-2EBI 2 1 30 0 0 0 0 0 0 0 5 6 2D 3DTSV
49 PP2C-deltaEBI 4 2 31 0 0 0 0 0 0 0 4 5 2D 3DTSV
50 Proliferating cell nuclear antigenEBI 7 0 33 0 0 0 0 0 0 0 2 4 2D 3DTSV
51 Protein phosphatase 1DEBI 4 2 31 0 0 0 0 0 0 0 4 5 2D 3DTSV
52 Protein phosphatase 2C isoform deltaEBI 4 2 31 0 0 0 0 0 0 0 4 5 2D 3DTSV
53 Protein phosphatase magnesium-dependent 1 deltaEBI 4 2 31 0 0 0 0 0 0 0 4 5 2D 3DTSV
54 Protein TREB36EBI 0 0 31 0 0 0 0 0 0 0 1 5 2D 3DTSV
55 RAD30 homolog BEBI 0 0 4 0 0 0 0 0 0 0 2 5 2D 3DTSV
56 RAD30BEBI 0 0 4 0 0 0 0 0 0 0 2 5 2D 3DTSV
57 Retinal short-chain dehydrogenase/reductase retSDR3EBI 0 32 0 0 0 0 0 0 0 0 2 1 2D 3DTSV
58 SDR3EBI 0 32 0 0 0 0 0 0 0 0 2 1 2D 3DTSV
59 SDR47C1EBI 0 32 0 0 0 0 0 0 0 0 2 1 2D 3DTSV
60 Short chain dehydrogenase/reductase family 47C member 1EBI 0 32 0 0 0 0 0 0 0 0 2 1 2D 3DTSV
61 Sulfonylurea receptor 1EBI 1 0 33 5 0 0 0 0 0 0 3 10 2D 3DTSV
62 Transcriptional activator protein lasREBI 12 0 23 0 18 0 0 0 0 0 5 4 2D 3DTSV
63 TrmDBDB 0 0 31 0 0 0 0 0 0 0 1 1 2D 3DTSV
64 UDSEBI 0 0 32 0 0 0 0 0 0 0 1 1 2D 3DTSV
65 Undecaprenyl diphosphate synthaseEBI 0 0 32 0 0 0 0 0 0 0 1 1 2D 3DTSV
66 Undecaprenyl pyrophosphate synthaseEBI 0 0 32 0 0 0 0 0 0 0 1 1 2D 3DTSV
67 UPP synthaseEBI 0 0 32 0 0 0 0 0 0 0 1 1 2D 3DTSV
Sub total19650315001014400000
Total2157