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Targets Binding with 3214 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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KiIC50KdEC50koffkonotherITCSDFTSV
1 (ARTD1 or PARP1)BDB 171 1168 2470 147 280 0 0 0 0 0 126 4 2D 3DTSV
2 (ARTD4 or PARP4)BDB 1 0 26 0 0 0 0 0 0 0 6 6 2D 3DTSV
3 (ARTD7 or PARP15)BDB 4 0 46 0 0 0 0 0 0 0 5 4 2D 3DTSV
4 (ARTD7 or PARP15, Y598L)BDB 4 0 46 0 0 0 0 0 0 0 5 4 2D 3DTSV
5 (ARTD8 or PARP14)BDB 3 0 37 2 0 0 0 0 0 0 5 8 2D 3DTSV
6 (ARTD8 or PARP14, Y1660L)BDB 3 0 37 2 0 0 0 0 0 0 5 8 2D 3DTSV
7 193 kDa vault proteinBDB 1 0 26 0 0 0 0 0 0 0 6 6 2D 3DTSV
8 ADP-ribosyltransferase diphtheria toxin-like 1BDB 171 1168 2470 147 280 0 0 0 0 0 126 4 2D 3DTSV
9 ADP-ribosyltransferase diphtheria toxin-like 15EBI 0 0 6 0 0 0 0 0 0 0 2 5 2D 3DTSV
10 ADP-ribosyltransferase diphtheria toxin-like 4BDB 1 0 26 0 0 0 0 0 0 0 6 6 2D 3DTSV
11 ADP-ribosyltransferase diphtheria toxin-like 7BDB 4 0 46 0 0 0 0 0 0 0 5 4 2D 3DTSV
12 ADP-ribosyltransferase diphtheria toxin-like 8BDB 3 0 37 2 0 0 0 0 0 0 5 8 2D 3DTSV
13 ADPRTBDB 171 1168 2470 147 280 0 0 0 0 0 126 4 2D 3DTSV
14 ADPRT 1BDB 171 1168 2470 147 280 0 0 0 0 0 126 4 2D 3DTSV
15 ADPRT-3EBI 0 0 20 0 0 0 0 0 0 0 2 5 2D 3DTSV
16 ADPRT3EBI 0 0 20 0 0 0 0 0 0 0 2 5 2D 3DTSV
17 ADPRTL1BDB 1 0 26 0 0 0 0 0 0 0 6 6 2D 3DTSV
18 ADPRTL1 BDB 1 0 26 0 0 0 0 0 0 0 6 6 2D 3DTSV
19 ADPRTL3EBI 0 0 20 0 0 0 0 0 0 0 2 5 2D 3DTSV
20 ARTD1BDB 171 1168 2470 147 280 0 0 0 0 0 126 4 2D 3DTSV
21 ARTD3EBI 0 0 20 0 0 0 0 0 0 0 2 5 2D 3DTSV
22 ARTD4BDB 1 0 26 0 0 0 0 0 0 0 6 6 2D 3DTSV
23 ARTD7BDB 4 0 46 0 0 0 0 0 0 0 5 4 2D 3DTSV
24 ARTD8BDB 3 0 37 2 0 0 0 0 0 0 5 8 2D 3DTSV
25 B aggressive lymphoma protein 2BDB 3 0 37 2 0 0 0 0 0 0 5 8 2D 3DTSV
26 B-aggressive lymphoma protein 3BDB 4 0 46 0 0 0 0 0 0 0 5 4 2D 3DTSV
27 BAL2BDB 3 0 37 2 0 0 0 0 0 0 5 8 2D 3DTSV
28 BAL2 BDB 3 0 37 2 0 0 0 0 0 0 5 8 2D 3DTSV
29 BAL3BDB 4 0 46 0 0 0 0 0 0 0 5 4 2D 3DTSV
30 C15orf30EBI 0 0 6 0 0 0 0 0 0 0 2 5 2D 3DTSV
31 hPARP-3EBI 0 0 20 0 0 0 0 0 0 0 2 5 2D 3DTSV
32 Human diphtheria toxin-like ADP-ribosyltransferase (ARTD1 or PARP1)BDB 171 1168 2470 147 280 0 0 0 0 0 126 4 2D 3DTSV
33 Human diphtheria toxin-like ADP-ribosyltransferase (ARTD4 or PARP4)BDB 1 0 27 0 0 0 0 0 0 0 7 6 2D 3DTSV
34 Human diphtheria toxin-like ADP-ribosyltransferase (ARTD7 or PARP15)BDB 4 0 47 0 0 0 0 0 0 0 6 4 2D 3DTSV
35 Human diphtheria toxin-like ADP-ribosyltransferase (ARTD7 or PARP15, Y598L)BDB 4 0 46 0 0 0 0 0 0 0 5 4 2D 3DTSV
36 Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14)BDB 3 0 38 2 0 0 0 0 0 0 6 8 2D 3DTSV
37 Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14, Y1660L)BDB 3 0 37 2 0 0 0 0 0 0 5 8 2D 3DTSV
38 IRT1EBI 0 0 20 0 0 0 0 0 0 0 2 5 2D 3DTSV
39 KIAA0177BDB 1 0 26 0 0 0 0 0 0 0 6 6 2D 3DTSV
40 KIAA1268BDB 3 0 37 2 0 0 0 0 0 0 5 8 2D 3DTSV
41 Mono [ADP-ribose] polymerase PARP16EBI 0 0 6 0 0 0 0 0 0 0 2 5 2D 3DTSV
42 NAD(+) ADP-ribosyltransferase 1BDB 171 1168 2470 147 280 0 0 0 0 0 126 4 2D 3DTSV
43 NAD(+) ADP-ribosyltransferase 3EBI 0 0 20 0 0 0 0 0 0 0 2 5 2D 3DTSV
44 pADPRT-3EBI 0 0 20 0 0 0 0 0 0 0 2 5 2D 3DTSV
45 PARP-1BDB 171 1168 2470 147 280 0 0 0 0 0 126 4 2D 3DTSV
46 PARP-14BDB 3 0 37 2 0 0 0 0 0 0 5 8 2D 3DTSV
47 PARP-15BDB 4 0 46 0 0 0 0 0 0 0 5 4 2D 3DTSV
48 PARP-16EBI 0 0 6 0 0 0 0 0 0 0 2 5 2D 3DTSV
49 PARP-3EBI 0 0 20 0 0 0 0 0 0 0 2 5 2D 3DTSV
50 PARP-4BDB 1 0 26 0 0 0 0 0 0 0 6 6 2D 3DTSV
51 PARP-related/IalphaI-related H5/proline-richBDB 1 0 26 0 0 0 0 0 0 0 6 6 2D 3DTSV
52 PARP1BDB 171 1168 2470 147 280 0 0 0 0 0 126 4 2D 3DTSV
53 PARP14BDB 3 0 37 2 0 0 0 0 0 0 5 8 2D 3DTSV
54 PARP15BDB 4 0 46 0 0 0 0 0 0 0 5 4 2D 3DTSV
55 PARP16EBI 0 0 6 0 0 0 0 0 0 0 2 5 2D 3DTSV
56 PARP3EBI 0 0 20 0 0 0 0 0 0 0 2 5 2D 3DTSV
57 PARP4BDB 1 0 26 0 0 0 0 0 0 0 6 6 2D 3DTSV
58 PARPLBDB 1 0 26 0 0 0 0 0 0 0 6 6 2D 3DTSV
59 PH5PBDB 1 0 26 0 0 0 0 0 0 0 6 6 2D 3DTSV
60 Poly [ADP-ribose] polymerase (PARP)BDB 171 1168 2470 147 280 0 0 0 0 0 126 4 2D 3DTSV
61 Poly [ADP-ribose] polymerase 1 (PARP)BDB 171 1168 2470 147 280 0 0 0 0 0 126 4 2D 3DTSV
62 Poly [ADP-ribose] polymerase 1 (PARP-1)BDB 171 1168 2470 147 280 0 0 0 0 0 126 4 2D 3DTSV
63 Poly [ADP-ribose] polymerase 14BDB 3 0 37 2 0 0 0 0 0 0 5 8 2D 3DTSV
64 Poly [ADP-ribose] polymerase 15BDB 4 0 46 0 0 0 0 0 0 0 5 4 2D 3DTSV
65 Poly [ADP-ribose] polymerase 16EBI 0 0 6 0 0 0 0 0 0 0 2 5 2D 3DTSV
66 Poly [ADP-ribose] polymerase 4BDB 1 0 26 0 0 0 0 0 0 0 6 6 2D 3DTSV
67 Poly(ADP-ribose) polymerase 1 (PARP1)BDB 171 1168 2470 147 280 0 0 0 0 0 126 4 2D 3DTSV
68 Poly(ADP-ribose) polymerase-1 (ARTD1/PARP1)BDB 171 1168 2470 147 280 0 0 0 0 0 126 4 2D 3DTSV
69 Poly[ADP-ribose] synthase 1BDB 171 1168 2470 147 280 0 0 0 0 0 126 4 2D 3DTSV
70 Poly[ADP-ribose] synthase 3EBI 0 0 20 0 0 0 0 0 0 0 2 5 2D 3DTSV
71 PPOLBDB 171 1168 2470 147 280 0 0 0 0 0 126 4 2D 3DTSV
72 Synonyms=ARTD15EBI 0 0 6 0 0 0 0 0 0 0 2 5 2D 3DTSV
73 Vault poly(ADP-ribose) polymeraseBDB 1 0 26 0 0 0 0 0 0 0 6 6 2D 3DTSV
74 VPARPBDB 1 0 26 0 0 0 0 0 0 0 6 6 2D 3DTSV
Sub total283518688411882378448000000
Total66734