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Targets Binding with 352 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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KiIC50KdEC50koffkonotherITCSDFTSV
1 2.7.12.2EBI 0 1 247 0 0 0 0 0 0 0 6 12 2D 3DTSV
2 CDK8BDB 77 0 212 127 71 0 0 0 0 0 15 4 2D 3DTSV
3 Cell division protein kinase 8BDB 77 0 212 127 71 0 0 0 0 0 15 5 2D 3DTSV
4 Cyclin-dependent kinase 8BDB 77 0 212 127 71 0 0 0 0 0 15 5 2D 3DTSV
5 Cyclin-Dependent Kinase 8 (CDK8)BDB 77 0 212 127 71 0 0 0 0 0 15 4 2D 3DTSV
6 Dual specificity mitogen-activated protein kinase kinase 2BDB 82 14 33 131 0 0 0 0 0 0 19 4 2D 3DTSV
7 ERK activator kinase 2BDB 82 14 33 131 0 0 0 0 0 0 19 4 2D 3DTSV
8 HD9BDB 35 31 474 0 0 0 0 0 0 0 71 19 2D 3DTSV
9 Histone acetylase 9 (HDAC9)BDB 35 31 474 0 0 0 0 0 0 0 71 15 2D 3DTSV
10 Histone deacetylase 7BBDB 35 31 474 0 0 0 0 0 0 0 71 19 2D 3DTSV
11 Histone deacetylase 9BDB 35 31 474 0 0 0 0 0 0 0 71 19 2D 3DTSV
12 Histone deacetylase 9 (HDAC9)BDB 35 31 474 0 0 0 0 0 0 0 71 15 2D 3DTSV
13 Histone deacetylase-related proteinBDB 35 31 474 0 0 0 0 0 0 0 71 19 2D 3DTSV
14 Human HDAC9BDB 35 31 474 0 0 0 0 0 0 0 71 15 2D 3DTSV
15 MAP kinase kinase 2BDB 82 14 33 131 0 0 0 0 0 0 19 4 2D 3DTSV
16 Map2k2EBI 0 0 13 0 0 0 0 0 0 0 1 3 2D 3DTSV
17 MAPK/ERK kinase 2BDB 82 14 33 131 0 0 0 0 0 0 19 4 2D 3DTSV
18 MAPKK 2BDB 82 14 33 131 0 0 0 0 0 0 19 4 2D 3DTSV
19 Mediator complex subunit CDK8BDB 77 0 212 127 71 0 0 0 0 0 15 5 2D 3DTSV
20 Mediator of RNA polymerase II transcription subunit CDK8BDB 77 0 212 127 71 0 0 0 0 0 15 5 2D 3DTSV
21 MEK 2EBI 0 0 13 0 0 0 0 0 0 0 1 3 2D 3DTSV
22 Mek2EBI 0 0 13 0 0 0 0 0 0 0 1 3 2D 3DTSV
23 Mkk2EBI 0 0 13 0 0 0 0 0 0 0 1 3 2D 3DTSV
24 Prkmk2EBI 0 0 13 0 0 0 0 0 0 0 1 3 2D 3DTSV
25 Protein kinase K35BDB 77 0 212 127 71 0 0 0 0 0 15 4 2D 3DTSV
26 RET kinase (V804L)BDB 0 0 365 0 0 0 0 0 0 0 4 0 2D 3DTSV
27 RET kinase mutant (V804L)BDB 0 0 365 0 0 0 0 0 0 0 4 0 2D 3DTSV
Sub total11942886009154449700000
Total8338