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Targets Binding with 36 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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AffyNet
KiIC50KdEC50koffkonotherITCSDFTSV
1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2EBI 0 0 36 0 0 0 0 0 0 0 1 6 2D 3DTSV
2 6PF-2-K/Fru-2,6-P2ase 2EBI 0 0 36 0 0 0 0 0 0 0 1 6 2D 3DTSV
3 6PF-2-K/Fru-2,6-P2ase heart-type isozymeEBI 0 0 36 0 0 0 0 0 0 0 1 6 2D 3DTSV
4 Adenosine transporter 1EBI 1 36 0 0 0 0 0 0 0 0 2 0 2D 3DTSV
5 Anti-silencing function protein 1 homolog AEBI 1 0 36 0 0 0 0 0 0 0 1 4 2D 3DTSV
6 ASF1AEBI 1 0 36 0 0 0 0 0 0 0 1 4 2D 3DTSV
7 C-Raf (Y340D/Y341D)BDB 0 0 38 0 0 0 0 0 0 0 1 0 2D 3DTSV
8 calcineurinEBI 0 3 34 7 0 0 0 0 0 0 7 8 2D 3DTSV
9 cAMP-specific 3',5'-cyclic phosphodiesterase 7BBDB 4 5 32 0 0 0 0 0 0 0 16 3 2D 3DTSV
10 Candida albicans strain ATCC 10261 multidrug efflux pump (MDR1) gene, MDR1-A allele, complete cdsEBI 15 0 0 0 37 0 0 0 0 0 2 1 2D 3DTSV
11 CCG1-interacting factor AEBI 1 0 36 0 0 0 0 0 0 0 1 4 2D 3DTSV
12 CDR1EBI 12 0 4 0 35 0 0 0 0 0 3 1 2D 3DTSV
13 CIAEBI 1 0 36 0 0 0 0 0 0 0 1 4 2D 3DTSV
14 CpG DNA methylaseBDB 0 30 7 0 0 0 0 0 0 0 4 1 2D 3DTSV
15 Cyclic AMP-dependent protein kinase (PKA)BDB 11 12 28 0 0 0 0 0 0 0 4 1 2D 3DTSV
16 drug resistance protein 1EBI 12 0 4 0 35 0 0 0 0 0 3 1 2D 3DTSV
17 Epidermal growth factor receptor (EGFR) T790MBDB 0 0 37 0 0 0 0 0 0 0 4 0 2D 3DTSV
18 Epidermal growth factor receptor (EGFR)(T790)BDB 0 0 37 0 0 0 0 0 0 0 4 0 2D 3DTSV
19 Epidermal growth factor receptor (EGFR)(T790M)BDB 0 0 37 0 0 0 0 0 0 0 4 0 2D 3DTSV
20 Epidermal growth factor receptor (T790M)BDB 0 0 37 0 0 0 0 0 0 0 4 0 2D 3DTSV
21 G-protein coupled receptor 18EBI 4 0 35 0 1 0 0 0 0 0 2 5 2D 3DTSV
22 GPCRWEBI 4 0 35 0 1 0 0 0 0 0 2 5 2D 3DTSV
23 GPR18EBI 4 0 35 0 1 0 0 0 0 0 2 5 2D 3DTSV
24 hAsf1EBI 1 0 36 0 0 0 0 0 0 0 1 4 2D 3DTSV
25 hAsf1aEBI 1 0 36 0 0 0 0 0 0 0 1 4 2D 3DTSV
26 hCIAEBI 1 0 36 0 0 0 0 0 0 0 1 4 2D 3DTSV
27 Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4BDB 1 3 37 0 0 0 0 0 0 0 7 4 2D 3DTSV
28 Histone chaperone ASF1AEBI 1 0 36 0 0 0 0 0 0 0 1 4 2D 3DTSV
29 HIV-1 Reverse Transcriptase Mutant (103N/181C)BDB 1 0 32 0 13 0 0 0 0 0 2 0 2D 3DTSV
30 HRMT1L3 BDB 1 3 37 0 0 0 0 0 0 0 7 4 2D 3DTSV
31 HRMT1L4BDB 1 3 37 0 0 0 0 0 0 0 7 4 2D 3DTSV
32 HSPC146EBI 1 0 36 0 0 0 0 0 0 0 1 4 2D 3DTSV
33 Human herpesvirus 6 DNA polymeraseEBI 8 0 36 0 0 0 0 0 0 0 1 3 2D 3DTSV
34 IgA proteaseEBI 0 0 45 0 0 0 0 0 0 0 2 1 2D 3DTSV
35 Insulin-like growth factor 1 receptorEBI 3 1 35 0 0 0 0 0 0 0 5 5 2D 3DTSV
36 M.SssI methyltransferaseBDB 0 30 7 0 0 0 0 0 0 0 4 1 2D 3DTSV
37 Matrix metalloproteinase 11EBI 0 36 1 0 0 0 0 0 0 0 6 6 2D 3DTSV
38 Multidrug resistance protein CDR1EBI 12 0 4 0 35 0 0 0 0 0 3 1 2D 3DTSV
39 MutT homolog 1 protein (MTH1)BDB 0 0 53 0 0 0 0 0 0 0 4 9 2D 3DTSV
40 N-arachidonyl glycine receptorEBI 4 0 35 0 1 0 0 0 0 0 2 5 2D 3DTSV
41 NADH OxidaseBDB 0 0 37 0 0 0 0 0 0 0 4 1 2D 3DTSV
42 NADH-ubiquinone oxidoreductaseBDB 0 0 37 0 0 0 0 0 0 0 4 1 2D 3DTSV
43 NADH-ubiquinone oxidoreductase chain 1BDB 0 0 37 0 0 0 0 0 0 0 4 1 2D 3DTSV
44 NAGly receptorEBI 4 0 35 0 1 0 0 0 0 0 2 5 2D 3DTSV
45 PFK/FBPase 2EBI 0 0 36 0 0 0 0 0 0 0 1 6 2D 3DTSV
46 PFKFB2EBI 0 0 36 0 0 0 0 0 0 0 1 6 2D 3DTSV
47 Phosphodiesterase 7BBDB 4 5 32 0 0 0 0 0 0 0 16 3 2D 3DTSV
48 Phosphodiesterase 7B (PDE7B)BDB 4 5 32 0 0 0 0 0 0 0 16 3 2D 3DTSV
49 PKA catalytic subunit alphaBDB 11 12 28 0 0 0 0 0 0 0 4 1 2D 3DTSV
50 PRMT8BDB 1 3 37 0 0 0 0 0 0 0 7 4 2D 3DTSV
51 Protein arginine methyltransferase 8 (PRMT8)BDB 1 3 37 0 0 0 0 0 0 0 7 4 2D 3DTSV
52 Protein arginine N-methyltransferase 8BDB 1 3 37 0 0 0 0 0 0 0 7 4 2D 3DTSV
53 Protein arginine N-methyltransferase 8 (PRMT8)BDB 1 3 37 0 0 0 0 0 0 0 7 4 2D 3DTSV
54 Purinergic, P2XEBI 16 4 22 0 11 0 0 0 0 0 15 3 2D 3DTSV
55 Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoformEBI 0 3 34 7 0 0 0 0 0 0 7 8 2D 3DTSV
56 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoformEBI 0 3 34 7 0 0 0 0 0 0 7 8 2D 3DTSV
57 Sialidase 1EBI 4 0 42 0 0 0 0 0 0 0 6 1 2D 3DTSV
58 Squalene--hopene cyclaseEBI 4 0 36 0 0 0 0 0 0 0 2 3 2D 3DTSV
59 Squalene-hopene cyclaseEBI 4 0 36 0 0 0 0 0 0 0 2 3 2D 3DTSV
60 sub-1EBI 1 2 34 0 0 0 0 0 0 0 3 0 2D 3DTSV
61 Subtilisin-like serine proteaseEBI 0 2 27 0 0 0 0 0 0 0 2 0 2D 3DTSV
62 Transcriptional activator protein traREBI 5 0 39 0 2 0 0 0 0 0 4 1 2D 3DTSV
63 West Nile Virus (WNV) NS2B-NS3 ProteaseBDB 4 26 31 7 0 0 0 0 0 0 4 0 2D 3DTSV
Sub total17223619842817300000
Total2421