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Targets Binding with 525 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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KiIC50KdEC50koffkonotherITCSDFTSV
1 EGFR (L858R, T790M)BDB 0 0 550 13 18 0 0 0 0 0 22 0 2D 3DTSV
2 Epidermal growth factor receptor (EGFR) (T790M/L858R)BDB 0 0 550 13 18 0 0 0 0 0 22 0 2D 3DTSV
3 Epidermal growth factor receptor (EGFR)(T790M/L858R)BDB 0 0 576 13 20 0 0 0 0 0 25 0 2D 3DTSV
4 Epidermal growth factor receptor (T790M)(L858R)BDB 0 0 550 13 18 0 0 0 0 0 22 0 2D 3DTSV
5 Epidermal growth factor receptor (T790M, L858R)BDB 0 0 550 13 18 0 0 0 0 0 22 0 2D 3DTSV
6 Epidermal growth factor receptor (T790M/L858R)BDB 0 0 573 13 18 0 0 0 0 0 23 0 2D 3DTSV
7 Epidermal growth factor receptor(L858R, T790M)BDB 0 0 550 13 18 0 0 0 0 0 22 0 2D 3DTSV
8 Glutamate receptor 1 (GluA1)BDB 0 90 152 0 36 0 0 0 0 0 23 1 2D 3DTSV
9 Glutamate receptor AMPA 1/2BDB 0 306 220 4 360 0 0 0 0 0 55 14 2D 3DTSV
10 Glutamate receptor ionotropic, AMPA 1BDB 4 175 210 0 78 0 0 0 0 0 40 11 2D 3DTSV
Sub total457144819560200000
Total5749