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Targets Binding with 65 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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AffyNet
KiIC50KdEC50koffkonotherITCSDFTSV
1 2-OG-Dependent Histone Demethylase JMJD2EBDB 28 5 69 0 0 0 0 0 0 0 10 1 2D 3DTSV
2 5-enolpyruvylshikimate-3-phosphate synthaseEBI 10 30 44 17 0 3 4 0 0 0 8 4 2D 3DTSV
3 A disintegrin and metalloproteinase with thrombospondin motifs 5BDB 8 0 57 0 0 0 0 8 0 0 2 0 2D 3DTSV
4 ADAM-TS 11BDB 8 0 57 0 0 0 0 8 0 0 2 0 2D 3DTSV
5 ADAMTS-5 (Aggrecanase-2)BDB 8 0 57 0 0 0 0 8 0 0 2 0 2D 3DTSV
6 ADMP-2BDB 8 0 57 0 0 0 0 8 0 0 2 0 2D 3DTSV
7 AMPK alpha2/beta1/gamma1EBI 2 0 1 0 65 0 0 0 0 0 6 3 2D 3DTSV
8 AMPK complex 7 (alpha-2,beta-1,gamma-1)EBI 2 0 1 0 65 0 0 0 0 0 6 3 2D 3DTSV
9 AMPK complex 7 (containing alpha-2, beta-1, gamma-1)EBI 2 0 1 0 65 0 0 0 0 0 6 3 2D 3DTSV
10 Cholinergic, muscarinic M5EBI 11 4 45 0 29 0 0 0 0 0 13 1 2D 3DTSV
11 Cyclic nucleotide specific phosphodiesteraseBDB 34 0 65 0 0 0 0 0 0 0 2 1 2D 3DTSV
12 Histone Lysine DemethylaseBDB 28 5 69 0 0 0 0 0 0 0 10 1 2D 3DTSV
13 Jumonji domain-containing protein 2E (JMJD2E)BDB 28 5 69 0 0 0 0 0 0 0 10 1 2D 3DTSV
14 KDM4D-like proteinBDB 28 5 69 0 0 0 0 0 0 0 10 1 2D 3DTSV
15 Lysine-specific demethylase 4D-likeBDB 28 5 69 0 0 0 0 0 0 0 10 1 2D 3DTSV
16 Lysine-specific demethylase 4EBDB 28 5 69 0 0 0 0 0 0 0 10 1 2D 3DTSV
17 Lysine-specific demethylase 4E (KDM4E)BDB 28 5 69 0 0 0 0 0 0 0 10 1 2D 3DTSV
18 mothers against decapentaplegic homolog 3BDB 30 0 66 0 0 0 0 0 0 0 2 14 2D 3DTSV
19 mPARP-2BDB 18 0 68 1 0 0 0 0 0 0 6 3 2D 3DTSV
20 NAD(+) ADP-ribosyltransferase 2BDB 18 0 68 1 0 0 0 0 0 0 6 3 2D 3DTSV
21 pADPRT-2BDB 18 0 68 1 0 0 0 0 0 0 6 3 2D 3DTSV
22 PARP-2BDB 18 0 68 1 0 0 0 0 0 0 6 3 2D 3DTSV
23 Phosphodiesterase (TcrPDEC)BDB 34 0 65 0 0 0 0 0 0 0 2 1 2D 3DTSV
24 Poly (ADP-ribose) Polymerase-2 (PARP-2)BDB 18 0 68 1 0 0 0 0 0 0 6 3 2D 3DTSV
25 Poly [ADP-ribose] polymerase-2BDB 18 0 68 1 0 0 0 0 0 0 6 3 2D 3DTSV
26 Poly[ADP-ribose] synthetase 2BDB 18 0 68 1 0 0 0 0 0 0 6 3 2D 3DTSV
27 SialidaseEBI 31 54 85 0 0 0 0 0 0 0 6 5 2D 3DTSV
Sub total510123156024224003200
Total1963