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Targets Binding with 73 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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KiIC50KdEC50koffkonotherITCSDFTSV
1 Abcc2EBI 8 66 17 0 6 0 0 0 0 0 17 3 2D 3DTSV
2 Alpha-glucosidase MAL62EBI 7 7 78 0 0 0 0 0 0 0 6 1 2D 3DTSV
3 ALS2CR7EBI 69 0 0 79 0 0 0 0 0 0 2 11 2D 3DTSV
4 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 proteinEBI 69 0 0 79 0 0 0 0 0 0 2 11 2D 3DTSV
5 Apoptosis signal-regulating kinase 3EBI 69 0 0 79 0 0 0 0 0 0 2 7 2D 3DTSV
6 Asparaginyl Endopeptidase (AE)BDB 0 0 128 0 0 0 0 3 0 0 2 3 2D 3DTSV
7 ATP-dependent RNA helicase eIF4A-1EBI 3 0 39 0 74 0 0 0 0 0 9 8 2D 3DTSV
8 B19EBI 69 0 0 79 0 0 0 0 0 0 2 1 2D 3DTSV
9 CA-XVBDB 42 73 0 0 0 0 0 0 0 0 3 0 2D 3DTSV
10 Carbonate dehydratase XVBDB 42 73 0 0 0 0 0 0 0 0 3 0 2D 3DTSV
11 Carbonic Anhydrase XVBDB 42 73 0 0 0 0 0 0 0 0 3 0 2D 3DTSV
12 CDK15EBI 69 0 0 79 0 0 0 0 0 0 2 11 2D 3DTSV
13 Cell division protein kinase 15EBI 69 0 0 79 0 0 0 0 0 0 2 11 2D 3DTSV
14 Cf1EBI 0 1 2 0 81 0 0 0 0 0 2 2 2D 3DTSV
15 Chorion factor 1EBI 0 1 2 0 81 0 0 0 0 0 2 2 2D 3DTSV
16 CLIK-1EBI 69 0 0 79 0 0 0 0 0 0 2 9 2D 3DTSV
17 CLP-36-interacting kinase 1EBI 69 0 0 79 0 0 0 0 0 0 2 9 2D 3DTSV
18 CmoatEBI 8 66 17 0 6 0 0 0 0 0 17 3 2D 3DTSV
19 CmrpEBI 8 66 17 0 6 0 0 0 0 0 17 3 2D 3DTSV
20 Cyclin-dependent kinase 15EBI 69 0 0 79 0 0 0 0 0 0 2 11 2D 3DTSV
21 Cyclin-dependent kinase-like 1EBI 69 0 1 72 0 0 0 0 0 0 2 0 2D 3DTSV
22 Cyclin-dependent kinase-like 3EBI 69 0 0 79 0 0 0 0 0 0 2 5 2D 3DTSV
23 DDX2AEBI 3 0 39 0 74 0 0 0 0 0 9 8 2D 3DTSV
24 Deoxyribonuclease IEBI 2 0 60 0 0 0 0 0 0 0 3 5 2D 3DTSV
25 Deoxyribonuclease-1EBI 5 0 73 0 0 0 0 0 0 0 7 9 2D 3DTSV
26 DNase IEBI 2 0 60 0 0 0 0 0 0 0 3 5 2D 3DTSV
27 DNASE1EBI 2 0 60 0 0 0 0 0 0 0 3 5 2D 3DTSV
28 DNL1 EBI 2 0 60 0 0 0 0 0 0 0 3 5 2D 3DTSV
29 DRNIEBI 2 0 60 0 0 0 0 0 0 0 3 5 2D 3DTSV
30 eIF-4A-IEBI 3 0 39 0 74 0 0 0 0 0 9 8 2D 3DTSV
31 EIF4AEBI 3 0 39 0 74 0 0 0 0 0 9 8 2D 3DTSV
32 eIF4A-IEBI 3 0 39 0 74 0 0 0 0 0 9 8 2D 3DTSV
33 EIF4A1EBI 3 0 39 0 74 0 0 0 0 0 9 8 2D 3DTSV
34 Envelope glycoprotein gp160 (V370A)BDB 0 0 0 0 73 0 0 0 0 0 1 0 2D 3DTSV
35 Eukaryotic initiation factor 4A-IEBI 3 0 39 0 74 0 0 0 0 0 9 8 2D 3DTSV
36 GABA A receptor alpha-6/beta-2/gamma-2BDB 28 113 7 0 2 0 0 0 0 0 15 7 2D 3DTSV
37 Hormonally up-regulated neu tumor-associated kinaseEBI 69 0 0 79 0 0 0 0 0 0 2 1 2D 3DTSV
38 INN=Dornase alfaEBI 2 0 60 0 0 0 0 0 0 0 3 5 2D 3DTSV
39 Legumain-like protease precursorBDB 0 0 70 0 0 0 0 0 0 0 2 1 2D 3DTSV
40 Male germ cell-associated kinaseEBI 69 0 0 79 0 0 0 0 0 0 2 7 2D 3DTSV
41 MAPK/ERK kinase kinase 15EBI 69 0 0 79 0 0 0 0 0 0 2 7 2D 3DTSV
42 MAST1/MAST2EBI 69 0 0 79 0 0 0 0 0 0 2 4 2D 3DTSV
43 MEK kinase 15EBI 69 0 0 79 0 0 0 0 0 0 2 7 2D 3DTSV
44 MEKK 15EBI 69 0 0 79 0 0 0 0 0 0 2 7 2D 3DTSV
45 Microtubule-associated serine/threonine-protein kinase 1EBI 69 0 0 79 0 0 0 0 0 0 2 4 2D 3DTSV
46 Mitogen-activated protein kinase kinase kinase 15EBI 69 0 0 79 0 0 0 0 0 0 2 7 2D 3DTSV
47 Mrp2EBI 8 66 17 0 6 0 0 0 0 0 17 3 2D 3DTSV
48 NL4-3 (V370A)BDB 0 0 0 0 73 0 0 0 0 0 1 0 2D 3DTSV
49 NR2B4 EBI 0 1 2 0 81 0 0 0 0 0 2 2 2D 3DTSV
50 Nuclear receptor subfamily 2 group B member 4EBI 0 1 2 0 81 0 0 0 0 0 2 4 2D 3DTSV
51 PDLIM1-interacting kinase 1EBI 69 0 0 79 0 0 0 0 0 0 2 9 2D 3DTSV
52 PFTK2EBI 69 0 0 79 0 0 0 0 0 0 2 11 2D 3DTSV
53 Protein ultraspiracleEBI 0 1 2 0 81 0 0 0 0 0 2 2 2D 3DTSV
54 PRP4 kinaseBDB 0 0 1 72 0 0 0 0 0 0 2 10 2D 3DTSV
55 PRP4 kinase (PRP4)BDB 0 0 1 72 0 0 0 0 0 0 2 10 2D 3DTSV
56 PRP4 pre-mRNA-processing factor 4 homologBDB 0 0 1 72 0 0 0 0 0 0 2 10 2D 3DTSV
57 Putative uncharacterized serine/threonine-protein kinase SgK110EBI 69 0 0 79 0 0 0 0 0 0 2 1 2D 3DTSV
58 RmtAEBI 18 0 74 0 0 0 0 0 0 0 4 1 2D 3DTSV
59 Sarco/endoplasmic Reticulum Ca2+ ATPase 1EBI 8 0 51 28 0 0 0 0 0 0 5 3 2D 3DTSV
60 Sarcoplasmic/endoplasmic reticulum calcium ATP-aseEBI 8 0 51 28 0 0 0 0 0 0 5 3 2D 3DTSV
61 Serine/threonine-protein kinase 35EBI 69 0 0 79 0 0 0 0 0 0 2 9 2D 3DTSV
62 Serine/threonine-protein kinase 35 L1EBI 69 0 0 79 0 0 0 0 0 0 2 9 2D 3DTSV
63 Serine/threonine-protein kinase ALS2CR7EBI 69 0 0 79 0 0 0 0 0 0 2 11 2D 3DTSV
64 Serine/threonine-protein kinase MAKEBI 69 0 0 79 0 0 0 0 0 0 2 7 2D 3DTSV
65 Serine/threonine-protein kinase MAK-VEBI 69 0 0 79 0 0 0 0 0 0 2 1 2D 3DTSV
66 Serine/threonine-protein kinase NKIAMREEBI 69 0 0 79 0 0 0 0 0 0 2 5 2D 3DTSV
67 Serine/threonine-protein kinase PFTAIRE-2EBI 69 0 0 79 0 0 0 0 0 0 2 11 2D 3DTSV
68 Serine/threonine-protein kinase PRP4 homologBDB 0 0 1 72 0 0 0 0 0 0 2 10 2D 3DTSV
69 Syntrophin-associated serine/threonine-protein kinaseEBI 69 0 0 79 0 0 0 0 0 0 2 4 2D 3DTSV
70 USPEBI 0 15 14 0 0 0 0 0 0 0 1 5 2D 3DTSV
71 XR2CEBI 0 1 2 0 81 0 0 0 0 0 2 2 2D 3DTSV
Sub total233562412642707117600300
Total5774