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Targets Binding with 75 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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KiIC50KdEC50koffkonotherITCSDFTSV
1 4F2 LCEBI 0 0 68 0 0 0 0 0 0 0 4 6 2D 3DTSV
2 4F2 light chainEBI 0 0 68 0 0 0 0 0 0 0 4 6 2D 3DTSV
3 4F2LCEBI 0 0 68 0 0 0 0 0 0 0 4 6 2D 3DTSV
4 Calpain I 80 kDa subunitBDB 0 0 10 0 0 0 0 0 0 0 1 1 2D 3DTSV
5 Calpain-1BDB 5 56 25 0 0 0 0 0 0 0 9 5 2D 3DTSV
6 CD98 light chainEBI 0 0 68 0 0 0 0 0 0 0 4 6 2D 3DTSV
7 CD98LC EBI 0 0 68 0 0 0 0 0 0 0 4 6 2D 3DTSV
8 Cytochrome P450 3A5BDB 11 11 74 0 0 0 0 0 0 0 16 7 2D 3DTSV
9 Cytochrome P450 3A5 (CYP3A5)BDB 11 11 74 0 0 0 0 0 0 0 16 7 2D 3DTSV
10 Dihydropteroate synthaseEBI 8 0 74 14 0 0 0 0 0 0 5 7 2D 3DTSV
11 E3 ubiquitin-protein ligase SMURF1EBI 0 0 54 0 0 0 0 0 0 0 2 8 2D 3DTSV
12 G-protein coupled receptor 4BDB 1 0 108 0 0 0 0 0 0 0 4 7 2D 3DTSV
13 G-protein coupled receptor 4 (GPR4)BDB 1 0 84 0 0 0 0 0 0 0 4 5 2D 3DTSV
14 H-l(3)mbt-like protein 4EBI 16 0 76 0 0 0 0 0 0 0 3 4 2D 3DTSV
15 HECT-type E3 ubiquitin transferase SMURF1BDB 0 0 119 0 0 0 0 0 0 0 4 8 2D 3DTSV
16 hICKEBI 70 0 3 79 0 0 0 0 0 0 5 9 2D 3DTSV
17 hLAT1EBI 0 0 68 0 0 0 0 0 0 0 4 6 2D 3DTSV
18 hSMURF1EBI 0 0 54 0 0 0 0 0 0 0 2 8 2D 3DTSV
19 Inositol polyphosphate phosphatase-like protein 1BDB 0 0 108 0 0 0 0 0 0 0 4 5 2D 3DTSV
20 INPPL-1BDB 0 0 108 0 0 0 0 0 0 0 4 5 2D 3DTSV
21 INPPL1BDB 0 0 108 0 0 0 0 0 0 0 4 5 2D 3DTSV
22 Integral membrane protein E16EBI 0 0 68 0 0 0 0 0 0 0 4 6 2D 3DTSV
23 Intestinal cell kinaseEBI 70 0 3 79 0 0 0 0 0 0 5 9 2D 3DTSV
24 KIAA0999EBI 69 0 2 79 0 0 0 0 0 0 4 0 2D 3DTSV
25 KIAA0999 proteinEBI 69 0 2 79 0 0 0 0 0 0 4 0 2D 3DTSV
26 KIAA1625EBI 0 0 54 0 0 0 0 0 0 0 2 8 2D 3DTSV
27 L(3)mbt-like protein 4EBI 16 0 76 0 0 0 0 0 0 0 3 4 2D 3DTSV
28 L-type amino acid transporter 1EBI 4 13 68 0 0 0 0 0 0 0 5 8 2D 3DTSV
29 Large neutral amino acids transporter small subunit 1EBI 0 0 68 0 0 0 0 0 0 0 4 6 2D 3DTSV
30 Laryngeal cancer kinase 2EBI 70 0 3 79 0 0 0 0 0 0 5 9 2D 3DTSV
31 LAT1EBI 0 0 68 0 0 0 0 0 0 0 4 6 2D 3DTSV
32 LCK2EBI 70 0 3 79 0 0 0 0 0 0 5 9 2D 3DTSV
33 Lethal(3)malignant brain tumor-like protein 4EBI 16 0 76 0 0 0 0 0 0 0 3 4 2D 3DTSV
34 Leucine zipper-bearing kinaseEBI 69 0 0 81 0 0 0 0 0 0 3 10 2D 3DTSV
35 Lipoprotein lipaseEBI 14 0 96 0 3 0 0 0 0 0 7 10 2D 3DTSV
36 MAK-related kinaseEBI 70 0 3 79 0 0 0 0 0 0 5 9 2D 3DTSV
37 Mitogen-activated protein kinase kinase kinase 13EBI 69 0 0 81 0 0 0 0 0 0 3 10 2D 3DTSV
38 MLKEBI 69 0 0 81 0 0 0 0 0 0 3 10 2D 3DTSV
39 MPE16EBI 0 0 68 0 0 0 0 0 0 0 4 6 2D 3DTSV
40 MRKEBI 70 0 3 79 0 0 0 0 0 0 5 9 2D 3DTSV
41 N-lysine methyltransferase SETD8BDB 0 3 80 2 0 0 0 0 0 0 7 5 2D 3DTSV
42 o-CAPN1BDB 0 0 10 0 0 0 0 0 0 0 1 1 2D 3DTSV
43 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2BDB 0 0 108 0 0 0 0 0 0 0 4 5 2D 3DTSV
44 Protein 51CBDB 0 0 108 0 0 0 0 0 0 0 4 5 2D 3DTSV
45 Salt-inducible kinase 3EBI 69 0 2 79 0 0 0 0 0 0 4 0 2D 3DTSV
46 Secreted frizzled-related protein 1EBI 3 0 71 5 45 0 0 0 0 0 5 4 2D 3DTSV
47 Serine/threonine-protein kinase ICKEBI 70 0 3 79 0 0 0 0 0 0 5 9 2D 3DTSV
48 Serine/threonine-protein kinase QSKEBI 69 0 2 79 0 0 0 0 0 0 4 0 2D 3DTSV
49 Serine/threonine-protein kinase SIK3EBI 69 0 2 79 0 0 0 0 0 0 4 0 2D 3DTSV
50 Serine/threonine-protein kinase ULK3EBI 69 0 2 79 0 0 0 0 0 0 4 8 2D 3DTSV
51 SET domain-containing protein 8 (SetD8)BDB 0 3 80 2 0 0 0 0 0 0 7 5 2D 3DTSV
52 SH2 domain-containing inositol 5''''-phosphatase 2BDB 0 0 108 0 0 0 0 0 0 0 4 5 2D 3DTSV
53 SH2 domain-containing inositol phosphatase 2BDB 0 0 108 0 0 0 0 0 0 0 4 5 2D 3DTSV
54 SHIP-2BDB 0 0 108 0 0 0 0 0 0 0 4 5 2D 3DTSV
55 SHIP2BDB 0 0 108 0 0 0 0 0 0 0 4 5 2D 3DTSV
56 SIK-3EBI 69 0 2 79 0 0 0 0 0 0 4 0 2D 3DTSV
57 SIK3EBI 69 0 2 79 0 0 0 0 0 0 4 0 2D 3DTSV
58 SLC7A5EBI 0 0 68 0 0 0 0 0 0 0 4 6 2D 3DTSV
59 SMAD ubiquitination regulatory factor 1EBI 0 0 54 0 0 0 0 0 0 0 2 8 2D 3DTSV
60 SMAD-specific E3 ubiquitin-protein ligase 1EBI 0 0 54 0 0 0 0 0 0 0 2 8 2D 3DTSV
61 SMURF1EBI 0 0 54 0 0 0 0 0 0 0 2 8 2D 3DTSV
62 Solute carrier family 7 member 5EBI 0 0 68 0 0 0 0 0 0 0 4 6 2D 3DTSV
63 Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2)BDB 0 0 108 0 0 0 0 0 0 0 4 5 2D 3DTSV
64 y+ system cationic amino acid transporterEBI 0 0 68 0 0 0 0 0 0 0 4 6 2D 3DTSV
Sub total135597352614514800000
Total5122