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Targets Binding with 81 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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AffyNet
KiIC50KdEC50koffkonotherITCSDFTSV
1 4.2.1.1EBI 0 40 0 0 0 0 0 0 0 0 1 0 2D 3DTSV
2 53BP1EBI 4 0 81 1 0 0 0 0 0 0 2 7 2D 3DTSV
3 63 kDa Cam-PDEBDB 17 0 82 0 0 0 0 0 0 0 18 7 2D 3DTSV
4 Calcium/calmodulin-dependent 3 ,5 -cyclic nucleotide phosphodiesterase 1BBDB 17 0 82 0 0 0 0 0 0 0 18 4 2D 3DTSV
5 Cam-PDE 1BBDB 17 0 82 0 0 0 0 0 0 0 18 7 2D 3DTSV
6 Carbonate dehydrataseBDB 54 120 0 0 0 0 0 0 0 0 5 1 2D 3DTSV
7 CDC42-binding protein kinase gammaEBI 76 0 1 124 0 0 0 0 0 0 5 3 2D 3DTSV
8 CDC42BPGEBI 76 0 1 124 0 0 0 0 0 0 5 3 2D 3DTSV
9 ChitinaseBDB 11 7 103 4 0 0 0 0 0 0 14 13 2D 3DTSV
10 DMPK-like gammaEBI 76 0 1 124 0 0 0 0 0 0 5 3 2D 3DTSV
11 DMPK2EBI 76 0 1 124 0 0 0 0 0 0 5 3 2D 3DTSV
12 ERK3EBI 76 0 0 124 0 0 0 0 0 0 6 6 2D 3DTSV
13 ERK4BDB 76 0 0 123 0 0 0 0 0 0 6 4 2D 3DTSV
14 MAP three kinase 1EBI 76 0 1 128 0 0 0 0 0 0 6 9 2D 3DTSV
15 MAP3K4EBI 76 0 1 128 0 0 0 0 0 0 6 9 2D 3DTSV
16 MAPK/ERK kinase kinase 4EBI 76 0 1 128 0 0 0 0 0 0 6 9 2D 3DTSV
17 MEK kinase 4EBI 76 0 1 128 0 0 0 0 0 0 6 9 2D 3DTSV
18 MEKK 4EBI 76 0 1 128 0 0 0 0 0 0 6 9 2D 3DTSV
19 Methyl-lysine binding protein (53BP1)EBI 4 0 81 1 0 0 0 0 0 0 2 7 2D 3DTSV
20 Mitogen-activated protein kinase 4BDB 76 0 0 123 0 0 0 0 0 0 6 4 2D 3DTSV
21 Mitogen-activated protein kinase 6EBI 76 0 0 124 0 0 0 0 0 0 6 6 2D 3DTSV
22 Mitogen-activated protein kinase kinase kinase 4EBI 76 0 1 128 0 0 0 0 0 0 6 9 2D 3DTSV
23 MRCK gammaEBI 76 0 1 124 0 0 0 0 0 0 5 3 2D 3DTSV
24 MRCKGEBI 76 0 1 124 0 0 0 0 0 0 5 3 2D 3DTSV
25 MYO3BEBI 76 0 1 120 0 0 0 0 0 0 5 11 2D 3DTSV
26 Myosin-IIIBEBI 76 0 1 120 0 0 0 0 0 0 5 11 2D 3DTSV
27 Myotonic dystrophy kinase-related CDC42-binding kinase gammaEBI 76 0 1 124 0 0 0 0 0 0 5 3 2D 3DTSV
28 Myotonic dystrophy protein kinase-like alphaEBI 76 0 1 124 0 0 0 0 0 0 5 3 2D 3DTSV
29 Myotonic dystrophy protein kinase-like gammaEBI 76 0 1 124 0 0 0 0 0 0 5 3 2D 3DTSV
30 p53-binding protein 1EBI 4 0 81 1 0 0 0 0 0 0 2 7 2D 3DTSV
31 p53BP1EBI 4 0 81 1 0 0 0 0 0 0 2 7 2D 3DTSV
32 PDH-containing protein JUNE-1BDB 4 0 81 0 0 0 0 0 0 0 2 9 2D 3DTSV
33 PFTK1EBI 76 0 0 124 0 0 0 0 0 0 4 12 2D 3DTSV
34 PHD finger protein 23BDB 4 0 81 0 0 0 0 0 0 0 2 9 2D 3DTSV
35 PHD finger protein 23 (PHF23)BDB 4 0 81 0 0 0 0 0 0 0 2 9 2D 3DTSV
36 PHF23BDB 4 0 81 0 0 0 0 0 0 0 2 9 2D 3DTSV
37 Phosphatidylinositol-4-phosphate 5-kinase type-1 alphaEBI 77 0 0 125 0 0 0 0 0 0 4 6 2D 3DTSV
38 Phosphatidylinositol-5-phosphate 4-kinase type-2 betaEBI 77 0 0 126 0 0 0 0 0 0 4 4 2D 3DTSV
39 Phosphodiesterase 1BBDB 17 0 82 0 0 0 0 0 0 0 18 4 2D 3DTSV
40 Phosphodiesterase 1B (PDE1B1)BDB 17 0 82 0 0 0 0 0 0 0 18 4 2D 3DTSV
41 Phosphodiesterase Type 1 (PDE1B)BDB 17 0 82 0 0 0 0 0 0 0 18 4 2D 3DTSV
42 PIP5K1AEBI 77 0 0 125 0 0 0 0 0 0 4 6 2D 3DTSV
43 PIP5K2BEBI 77 0 0 126 0 0 0 0 0 0 4 4 2D 3DTSV
44 Proto-oncogene protein Wnt-3EBI 2 0 0 0 81 0 0 0 0 0 2 4 2D 3DTSV
45 RIOK3EBI 77 0 0 124 0 0 0 0 0 0 4 3 2D 3DTSV
46 Serine/threonine-protein kinase MRCK gammaEBI 76 0 1 124 0 0 0 0 0 0 5 3 2D 3DTSV
47 Serine/threonine-protein kinase PFTAIRE-1EBI 76 0 0 124 0 0 0 0 0 0 4 12 2D 3DTSV
48 Serine/threonine-protein kinase RIO3EBI 77 0 0 124 0 0 0 0 0 0 4 3 2D 3DTSV
49 TP53BP1EBI 4 0 81 1 0 0 0 0 0 0 2 7 2D 3DTSV
50 Tubulin beta-1 chainEBI 9 0 79 7 0 0 0 0 0 0 5 1 2D 3DTSV
51 Tumor suppressor p53-binding protein 1EBI 4 0 81 1 0 0 0 0 0 0 2 7 2D 3DTSV
52 Vacuolar-type proton translocating pyrophosphatase 1EBI 4 0 81 0 0 0 0 0 0 0 1 0 2D 3DTSV
53 Vitamin D receptorEBI 1 83 6 0 56 0 0 0 0 0 18 6 2D 3DTSV
Sub total25092501589375713700000
Total5733