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Targets Binding with 84 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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AffyNet
KiIC50KdEC50koffkonotherITCSDFTSV
1 Adrenaline alpha2EBI 2 33 38 0 0 0 0 0 0 0 12 4 2D 3DTSV
2 ATP-binding cassette sub-family C member 2BDB 31 30 75 0 12 0 0 0 0 0 26 11 2D 3DTSV
3 BLAST-2EBI 4 0 71 0 17 0 0 0 0 0 4 1 2D 3DTSV
4 Canalicular multidrug resistance proteinBDB 31 30 75 0 12 0 0 0 0 0 26 11 2D 3DTSV
5 Canalicular multispecific organic anion transporter 1BDB 31 30 75 0 12 0 0 0 0 0 26 11 2D 3DTSV
6 Cathepsin EBDB 1 27 70 0 0 0 0 0 0 0 31 11 2D 3DTSV
7 CDK8-likeBDB 78 0 0 130 0 0 0 0 0 0 6 6 2D 3DTSV
8 CD_antigen=CD23EBI 4 0 71 0 17 0 0 0 0 0 4 1 2D 3DTSV
9 Cell Division Cycle 2-Like 6 (CDK11)BDB 78 0 0 130 0 0 0 0 0 0 6 6 2D 3DTSV
10 Cell division cycle 2-like protein kinase 6BDB 78 0 0 130 0 0 0 0 0 0 6 6 2D 3DTSV
11 Export Pump, ABCC2BDB 23 11 65 0 6 0 0 0 0 0 19 9 2D 3DTSV
12 Fc-epsilon-RIIEBI 4 0 71 0 17 0 0 0 0 0 4 1 2D 3DTSV
13 hOCT2EBI 51 2 56 0 0 0 0 0 0 0 7 6 2D 3DTSV
14 Immunoglobulin E-binding factorEBI 4 0 71 0 17 0 0 0 0 0 4 1 2D 3DTSV
15 Immunoglobulin epsilon Fc receptorEBI 4 0 71 0 17 0 0 0 0 0 4 1 2D 3DTSV
16 Insulin receptor-related proteinEBI 76 0 6 118 0 0 0 0 0 0 9 4 2D 3DTSV
17 Low affinity immunoglobulin epsilon Fc receptorEBI 4 0 71 0 17 0 0 0 0 0 4 1 2D 3DTSV
18 Low affinity immunoglobulin epsilon Fc receptor membrane-bound formEBI 4 0 71 0 17 0 0 0 0 0 4 1 2D 3DTSV
19 Low affinity immunoglobulin epsilon Fc receptor soluble formEBI 4 0 71 0 17 0 0 0 0 0 4 1 2D 3DTSV
20 Lymphocyte IgE receptorEBI 4 0 71 0 17 0 0 0 0 0 4 1 2D 3DTSV
21 MAP4K1EBI 77 0 2 131 0 0 0 0 0 0 6 1 2D 3DTSV
22 Mitogen-activated protein kinase kinase kinase kinase 1EBI 77 0 2 131 0 0 0 0 0 0 6 1 2D 3DTSV
23 Mitogen-activated protein kinase p38 alpha (p38 alpha)BDB 76 0 6 131 0 0 0 0 0 0 11 7 2D 3DTSV
24 Multidrug resistance-associated protein 2BDB 31 30 75 0 12 0 0 0 0 0 26 11 2D 3DTSV
25 Multidrug resistance-associated protein 2 (MRP2)BDB 23 11 65 0 6 0 0 0 0 0 19 9 2D 3DTSV
26 Multidrug resistance-associated protein 3 (MRP3)BDB 23 11 65 0 6 0 0 0 0 0 19 9 2D 3DTSV
27 N-acylsphingosine-amidohydrolaseBDB 0 0 109 0 0 0 0 0 0 0 8 5 2D 3DTSV
28 NEK7EBI 77 0 2 123 0 0 0 0 0 0 8 3 2D 3DTSV
29 Non-receptor tyrosine-protein kinase TNK1EBI 78 0 2 131 0 0 0 0 0 0 9 4 2D 3DTSV
30 NUAK family SNF1-like kinase 2EBI 77 0 1 130 0 0 0 0 0 0 7 1 2D 3DTSV
31 Oct2EBI 8 33 44 0 0 0 0 0 0 0 13 7 2D 3DTSV
32 Organic cation transporter 2EBI 58 35 100 0 0 0 0 0 0 0 20 12 2D 3DTSV
33 PCTK1BDB 77 0 1 139 0 0 0 0 0 0 8 6 2D 3DTSV
34 PHKG1EBI 77 0 2 135 0 0 0 0 0 0 8 5 2D 3DTSV
35 Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gammaEBI 70 0 9 81 0 0 0 0 0 0 8 3 2D 3DTSV
36 Phosphoinositide 3-kinase-C2-gammaEBI 70 0 9 81 0 0 0 0 0 0 8 3 2D 3DTSV
37 Phosphorylase b kinase gamma catalytic chain, skeletal muscle isoformEBI 77 0 2 135 0 0 0 0 0 0 8 5 2D 3DTSV
38 Phosphorylase kinase gamma subunit 1EBI 77 0 2 135 0 0 0 0 0 0 8 5 2D 3DTSV
39 Phosphorylase kinase subunit gamma 1EBI 77 0 2 135 0 0 0 0 0 0 8 5 2D 3DTSV
40 PI3K-C2-gammaEBI 70 0 9 81 0 0 0 0 0 0 8 3 2D 3DTSV
41 PKMYT1EBI 77 0 4 120 1 0 0 0 0 0 9 10 2D 3DTSV
42 Protein-glutamine glutamyltransferase EBDB 4 0 84 0 0 0 0 0 0 0 4 8 2D 3DTSV
43 PtdIns-3-kinase C2 subunit gammaEBI 70 0 9 81 0 0 0 0 0 0 8 3 2D 3DTSV
44 rOCT2EBI 2 33 38 0 0 0 0 0 0 0 12 4 2D 3DTSV
45 Serine/threonine-protein kinase 10BDB 76 0 6 131 0 0 0 0 0 0 11 7 2D 3DTSV
46 Serine/threonine-protein kinase 10 (LOK)BDB 76 0 6 131 0 0 0 0 0 0 11 7 2D 3DTSV
47 Serine/threonine-protein kinase 10 (STK10)BDB 76 0 6 131 0 0 0 0 0 0 11 7 2D 3DTSV
48 Serine/threonine-protein kinase NEK7EBI 77 0 2 123 0 0 0 0 0 0 8 3 2D 3DTSV
49 Serine/threonine-protein kinase PCTAIRE-1BDB 77 0 1 139 0 0 0 0 0 0 8 6 2D 3DTSV
50 SLC22A2EBI 51 2 56 0 0 0 0 0 0 0 7 6 2D 3DTSV
51 SNARKEBI 77 0 1 130 0 0 0 0 0 0 7 1 2D 3DTSV
52 Solute carrier family 22 member 2EBI 58 35 100 0 0 0 0 0 0 0 20 12 2D 3DTSV
53 TNK1EBI 78 0 2 131 0 0 0 0 0 0 9 4 2D 3DTSV
54 Transglutaminase-3 (TG3)BDB 4 0 84 0 0 0 0 0 0 0 4 8 2D 3DTSV
55 Tyrosine- and threonine-specific cdc2-inhibitory kinaseEBI 77 0 4 120 1 0 0 0 0 0 9 10 2D 3DTSV
Sub total25963532011344422100000
Total6029