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Targets Binding with 89 Compounds


Target NameCommercially
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Compounds
Protein/Small MoleculeOther

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KiIC50KdEC50koffkonotherITCSDFTSV
1 5-HT5aEBI 29 149 0 0 0 0 0 0 0 0 13 5 2D 3DTSV
2 90 kDa ribosomal protein S6 kinase 6BDB 80 14 7 235 0 0 0 0 0 0 12 7 2D 3DTSV
3 AMFEBI 0 1 0 0 0 0 0 0 0 0 1 3 2D 3DTSV
4 Autocrine motility factorEBI 0 1 0 0 0 0 0 0 0 0 1 3 2D 3DTSV
5 BR serine/threonine-protein kinase 1BDB 78 2 7 122 0 0 0 0 0 0 11 9 2D 3DTSV
6 BR140-like proteinEBI 2 1 118 13 0 0 0 0 0 0 17 4 2D 3DTSV
7 BRD1EBI 2 1 118 13 0 0 0 0 0 0 17 4 2D 3DTSV
8 BRL EBI 2 1 118 13 0 0 0 0 0 0 17 4 2D 3DTSV
9 Bromodomain and PHD finger-containing protein 2EBI 2 1 118 13 0 0 0 0 0 0 17 4 2D 3DTSV
10 Bromodomain-containing protein 1EBI 2 1 118 13 0 0 0 0 0 0 17 4 2D 3DTSV
11 BRPF2EBI 2 1 118 13 0 0 0 0 0 0 17 4 2D 3DTSV
12 Calcium-dependent protein kinase 1BDB 71 2 15 72 16 0 0 0 0 0 3 3 2D 3DTSV
13 CD_antigen=CD282EBI 0 0 6 0 0 0 0 0 0 0 1 4 2D 3DTSV
14 Enoyl-ACP reductaseBDB 6 32 88 0 0 0 0 0 0 0 8 2 2D 3DTSV
15 ERK-8BDB 78 0 5 130 0 0 0 0 0 0 13 4 2D 3DTSV
16 ERK8BDB 78 0 5 130 0 0 0 0 0 0 13 4 2D 3DTSV
17 Extracellular signal-regulated kinase 8BDB 78 0 5 130 0 0 0 0 0 0 13 4 2D 3DTSV
18 Follicle stimulating hormone receptorEBI 1 0 27 0 82 0 0 0 0 0 8 14 2D 3DTSV
19 Follicle-stimulating hormone receptorEBI 1 0 26 0 82 0 0 0 0 0 8 12 2D 3DTSV
20 Follitropin receptorEBI 1 0 26 0 82 0 0 0 0 0 8 12 2D 3DTSV
21 FSH-REBI 1 0 26 0 82 0 0 0 0 0 8 12 2D 3DTSV
22 G protein-coupled receptor 34EBI 0 0 0 0 120 0 0 0 0 0 2 2 2D 3DTSV
23 Galanin R1EBI 7 97 33 7 0 0 0 0 0 0 15 4 2D 3DTSV
24 Galanin receptor type 1EBI 7 97 33 7 0 0 0 0 0 0 15 4 2D 3DTSV
25 GALR1EBI 7 97 33 7 0 0 0 0 0 0 15 4 2D 3DTSV
26 Glucose-6-phosphate isomeraseEBI 0 1 0 0 0 0 0 0 0 0 1 3 2D 3DTSV
27 GPIEBI 0 1 0 0 0 0 0 0 0 0 1 3 2D 3DTSV
28 GPR34EBI 0 0 0 0 68 0 0 0 0 0 2 4 2D 3DTSV
29 Heat Shock 70kDa Protein 1BDB 47 14 116 12 0 0 0 0 0 0 6 5 2D 3DTSV
30 Hsp70BDB 6 14 19 12 0 0 0 0 0 0 3 3 2D 3DTSV
31 HSP70-1/HSP70-2BDB 6 14 19 12 0 0 0 0 0 0 3 3 2D 3DTSV
32 HSP70.1BDB 6 14 19 12 0 0 0 0 0 0 3 3 2D 3DTSV
33 HTR5AEBI 15 49 0 0 0 0 0 0 0 0 8 2 2D 3DTSV
34 Leukocyte adhesion molecule-1EBI 4 0 103 0 0 0 0 0 0 0 10 8 2D 3DTSV
35 MAPK15BDB 78 0 5 130 0 0 0 0 0 0 13 4 2D 3DTSV
36 Mitogen-activated protein kinase 15BDB 78 0 5 130 0 0 0 0 0 0 13 4 2D 3DTSV
37 NeuroleukinEBI 0 1 0 0 0 0 0 0 0 0 1 3 2D 3DTSV
38 NLKEBI 80 2 5 129 0 0 0 0 0 0 12 8 2D 3DTSV
39 p90-RSK 6BDB 80 14 7 235 0 0 0 0 0 0 12 7 2D 3DTSV
40 Parathyroid hormone 1 receptorEBI 0 26 16 1 71 0 0 0 0 0 7 4 2D 3DTSV
41 Parathyroid hormone receptorEBI 0 26 16 1 71 0 0 0 0 0 7 4 2D 3DTSV
42 PfCDPK1BDB 71 2 15 72 16 0 0 0 0 0 3 3 2D 3DTSV
43 PGIEBI 0 1 0 0 0 0 0 0 0 0 1 3 2D 3DTSV
44 PHIEBI 0 1 0 0 0 0 0 0 0 0 1 3 2D 3DTSV
45 Phosphoglucose isomeraseEBI 0 1 0 0 0 0 0 0 0 0 1 3 2D 3DTSV
46 Phosphohexose isomeraseEBI 0 1 0 0 0 0 0 0 0 0 1 3 2D 3DTSV
47 pp90RSK4BDB 80 14 7 235 0 0 0 0 0 0 12 7 2D 3DTSV
48 Probable G-protein coupled receptor 34EBI 0 0 0 0 188 0 0 0 0 0 3 6 2D 3DTSV
49 PTH/PTHr receptorEBI 0 26 16 1 71 0 0 0 0 0 7 4 2D 3DTSV
50 PTH/PTHrP type I receptorEBI 0 26 16 1 71 0 0 0 0 0 7 4 2D 3DTSV
51 PTH1 receptorEBI 0 26 16 1 71 0 0 0 0 0 7 4 2D 3DTSV
52 REC17EBI 15 48 0 0 0 0 0 0 0 0 7 1 2D 3DTSV
53 Ribosomal protein S6 kinase alpha 6BDB 80 14 7 235 0 0 0 0 0 0 12 7 2D 3DTSV
54 Ribosomal protein S6 kinase alpha-6BDB 80 14 7 235 0 0 0 0 0 0 12 7 2D 3DTSV
55 Ribosomal S6 kinase 4BDB 80 14 7 235 0 0 0 0 0 0 12 7 2D 3DTSV
56 Ribosomal S6 Kinase 4 (RSK-4)BDB 80 14 7 235 0 0 0 0 0 0 12 7 2D 3DTSV
57 RPS6KA6(Kin.Dom.1 - N-terminal)BDB 80 14 7 235 0 0 0 0 0 0 12 7 2D 3DTSV
58 RPS6KA6(Kin.Dom.2 - C-terminal)BDB 80 14 7 235 0 0 0 0 0 0 12 7 2D 3DTSV
59 RSK-4BDB 80 14 7 235 0 0 0 0 0 0 12 7 2D 3DTSV
60 S6K-alpha 6BDB 80 14 7 235 0 0 0 0 0 0 12 7 2D 3DTSV
61 Serine/threonine-protein kinase BRSK1 (BRSK1)BDB 78 2 7 122 0 0 0 0 0 0 11 9 2D 3DTSV
62 Tlr2EBI 0 0 6 0 0 0 0 0 0 0 1 4 2D 3DTSV
63 Toll-like receptor 2BDB 0 5 35 0 70 0 0 0 0 0 10 12 2D 3DTSV
64 Toll-like receptor 2 (TLR2)BDB 0 5 29 0 70 0 0 0 0 0 10 9 2D 3DTSV
65 TransketolaseEBI 5 0 1 44 60 0 0 0 0 0 4 8 2D 3DTSV
66 Voltage-gated potassium channel beta subunit Mink/subunit Kv7.1EBI 37 0 97 0 1 0 0 0 0 0 8 0 2D 3DTSV
67 Voltage-gated potassium channel, IKs; KCNQ1(Kv7.1)/KCNE1(MinK)EBI 37 0 97 0 1 0 0 0 0 0 8 0 2D 3DTSV
Sub total189894417783948129300000
Total7963