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Targets Binding with 97 Compounds


Target NameCommercially
Available
Compounds
Protein/Small MoleculeOther

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AffyNet
KiIC50KdEC50koffkonotherITCSDFTSV
1 Aldo-keto reductase family 1 member B10BDB 33 11 115 0 0 0 0 0 0 0 11 6 2D 3DTSV
2 Aldo-keto reductase family 1 member B10 (AKR1B10)BDB 33 11 115 0 0 0 0 0 0 0 11 6 2D 3DTSV
3 Aldo-keto reductase family member 1B10 (AKR1B10)BDB 33 11 115 0 0 0 0 0 0 0 11 6 2D 3DTSV
4 Aldose reductase-likeBDB 33 11 115 0 0 0 0 0 0 0 11 6 2D 3DTSV
5 Aldose reductase-related proteinBDB 33 11 115 0 0 0 0 0 0 0 11 6 2D 3DTSV
6 ARL-1BDB 33 11 115 0 0 0 0 0 0 0 11 6 2D 3DTSV
7 ARPBDB 33 11 115 0 0 0 0 0 0 0 11 6 2D 3DTSV
8 Calpain 1EBI 7 44 53 0 0 0 0 0 0 0 5 3 2D 3DTSV
9 Calpain 1/small subunit 1EBI 5 44 35 0 0 0 0 0 0 0 4 2 2D 3DTSV
10 CDK3/Cyclin EBDB 78 1 15 124 0 0 0 0 0 0 12 2 2D 3DTSV
11 CDK3/EEBI 1 0 8 0 0 0 0 0 0 0 4 2 2D 3DTSV
12 Class 1 phosphodiesterase PDEB1BDB 10 0 100 0 0 0 0 0 0 0 6 0 2D 3DTSV
13 Class I phosphodiesterase B1 (TbrPDEB1)BDB 10 0 100 0 0 0 0 0 0 0 6 0 2D 3DTSV
14 Cytochrome P450 2J2BDB 0 7 113 0 0 0 0 0 0 0 9 4 2D 3DTSV
15 Cytosol aminopeptidaseBDB 7 73 29 0 0 0 0 0 0 0 8 4 2D 3DTSV
16 DNA (cytosine-5)-methyltransferase 3AEBI 48 0 96 0 4 0 0 0 0 0 7 7 2D 3DTSV
17 DNA methyltransferase HsaIIIAEBI 48 0 96 0 4 0 0 0 0 0 7 7 2D 3DTSV
18 DNA MTase HsaIIIAEBI 48 0 96 0 4 0 0 0 0 0 7 7 2D 3DTSV
19 Dnmt3aEBI 48 0 96 0 4 0 0 0 0 0 7 7 2D 3DTSV
20 EPH receptor B1EBI 2 2 14 137 0 0 0 0 0 0 19 9 2D 3DTSV
21 EPHB1EBI 2 2 14 137 0 0 0 0 0 0 19 9 2D 3DTSV
22 Ephrin type-B receptor 1EBI 2 2 14 137 0 0 0 0 0 0 19 9 2D 3DTSV
23 FK506 binding protein 4EBI 6 17 84 9 0 0 0 0 0 0 7 5 2D 3DTSV
24 hARPBDB 33 11 115 0 0 0 0 0 0 0 11 6 2D 3DTSV
25 High affinity choline transporter 1EBI 1 1 0 0 0 0 0 0 0 0 1 1 2D 3DTSV
26 High-affinity choline transporterEBI 46 2 54 0 60 0 0 0 0 0 7 3 2D 3DTSV
27 hVPS34BDB 15 1 107 0 0 0 0 0 0 0 30 3 2D 3DTSV
28 LAPcBDB 7 23 26 0 0 0 0 0 0 0 4 4 2D 3DTSV
29 Leucyl aminopeptidaseBDB 7 23 26 0 0 0 0 0 0 0 4 4 2D 3DTSV
30 Lysophosphatidic acid receptor 5BDB 0 1 89 0 13 0 0 0 0 0 6 1 2D 3DTSV
31 Lysophosphatidic acid receptor 5 (LPA5)BDB 0 1 89 0 13 0 0 0 0 0 6 1 2D 3DTSV
32 M.HsaIIIAEBI 48 0 96 0 4 0 0 0 0 0 7 7 2D 3DTSV
33 Matrix metallopeptidase 13 (MMP13)BDB 0 0 97 0 0 0 0 0 0 0 1 2 2D 3DTSV
34 PDEB1BDB 10 0 101 0 0 0 0 0 0 0 6 0 2D 3DTSV
35 Phosphatidylinositol 3-kinase catalytic subunit type 3BDB 15 1 107 0 0 0 0 0 0 0 30 3 2D 3DTSV
36 Phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3)BDB 15 1 107 0 0 0 0 0 0 0 30 3 2D 3DTSV
37 Phosphatidylinositol 3-kinase p100 subunitBDB 15 1 107 0 0 0 0 0 0 0 30 3 2D 3DTSV
38 Phosphoinositide 3-Kinase (PI3K), Vps34BDB 15 1 107 0 0 0 0 0 0 0 30 3 2D 3DTSV
39 Phosphoinositide-3-kinase class 3BDB 15 1 107 0 0 0 0 0 0 0 30 3 2D 3DTSV
40 PI3K type 3BDB 15 1 107 0 0 0 0 0 0 0 30 3 2D 3DTSV
41 Pituitary adenylate cyclase-activating polypeptide type I receptorEBI 0 15 82 4 69 0 0 0 0 0 4 6 2D 3DTSV
42 PtdIns-3-kinase type 3BDB 15 1 107 0 0 0 0 0 0 0 30 3 2D 3DTSV
43 SI reductaseBDB 33 11 115 0 0 0 0 0 0 0 11 6 2D 3DTSV
44 Small intestine reductaseBDB 33 11 115 0 0 0 0 0 0 0 11 6 2D 3DTSV
45 tyrosine-protein phosphatase non-receptor type 12 isoform 2EBI 48 0 96 0 4 0 0 0 0 0 7 7 2D 3DTSV
Sub total939376372554817900000
Total4828