PMID

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Article Title

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Discovery and analgesic evaluation of 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione as a novel potent d-amino acid oxidase inhibitor.

Shanghai Jiao Tong University

D-Amino acid oxidase inhibitors based on the 5-hydroxy-1,2,4-triazin-6(1H)-one scaffold.

Johns Hopkins University

Identification of Novel D-Aspartate Oxidase Inhibitors by in Silico Screening and Their Functional and Structural Characterization in Vitro.

Kitasato University

6-Hydroxy-1,2,4-triazine-3,5(2H,4H)-dione Derivatives as Novel D-Amino Acid Oxidase Inhibitors.

Johns Hopkins University

Structure-Metabolism Relationships in the Glucuronidation of d-Amino Acid Oxidase Inhibitors.

Johns Hopkins University

Synthesis of kojic acid derivatives as secondary binding site probes of D-amino acid oxidase.

Johns Hopkins University

Structural, kinetic, and pharmacodynamic mechanisms of D-amino acid oxidase inhibition by small molecules.

Sunovion Pharmaceuticals

Synthesis and SAR study of new thiazole derivatives as vascular adhesion protein-1 (VAP-1) inhibitors for the treatment of diabetic macular edema: part 2.

Astellas Pharma

4-Hydroxypyridazin-3(2H)-one derivatives as novel D-amino acid oxidase inhibitors.

Astellas Pharma

Identification of novel D-amino acid oxidase inhibitors by in silico screening and their functional characterization in vitro.

Kitasato University

Synthesis and SAR study of new thiazole derivatives as vascular adhesion protein-1 (VAP-1) inhibitors for the treatment of diabetic macular edema.

Astellas Pharma

Synthesis and SAR of 1-hydroxy-1H-benzo[d]imidazol-2(3H)-ones as Inhibitors of D-Amino Acid Oxidase.

TBA

The discovery and development of selective 3-fluoro-4-aryloxyallylamine inhibitors of the amine oxidase activity of semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 (SSAO/VAP-1).

Pharmaxis

Biophysical and physicochemical methods differentiate highly ligand-efficient human D-amino acid oxidase inhibitors.

Abbott Healthcare Products

The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors.

Merck Sharp & Dohme

Identification and Optimization of Mechanism-Based Fluoroallylamine Inhibitors of Lysyl Oxidase-like 2/3.

Pharmaxis

Structural basis for potent inhibition of d-amino acid oxidase by thiophene carboxylic acids.

Tokushima University

Discovery of d-amino acid oxidase inhibitors based on virtual screening against the lid-open enzyme conformation.

Hungarian Academy Of Sciences

Discovery of isatin and 1H-indazol-3-ol derivatives as d-amino acid oxidase (DAAO) inhibitors.

Hungarian Academy Of Sciences

3-Amidoquinuclidine derivatives: synthesis of compounds and inhibition of butyrylcholinesterase.

University Of Zagreb

1-(m-chlorophenyl)piperazine (mCPP) interactions with neurotransmitter receptors in the human brain.

Stanford University

Site-activated chelators targeting acetylcholinesterase and monoamine oxidase for Alzheimer's therapy.

The Weizmann Institute Of Science

Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.

Aventis Pharma