PMID

Data

Article Title

Organization

MLN8054 and Alisertib (MLN8237): Discovery of Selective Oral Aurora A Inhibitors.

Takeda Pharmaceutical

Ion channels as therapeutic targets: a drug discovery perspective.

Pfizer

Allyl m-trifluoromethyldiazirine mephobarbital: an unusually potent enantioselective and photoreactive barbiturate general anesthetic.

Massachusetts General Hospital

Selective influence on contextual memory: physiochemical properties associated with selectivity of benzodiazepine ligands at GABAA receptors containing the alpha5 subunit.

Moltech

Exploring subtype selectivity and metabolic stability of a novel series of ligands for the benzodiazepine binding site of the GABAA receptor.

Novartis Institutes For Biomedical Research

 

A conformational study of ligands for omega modulatory sites of GABAa receptors by NOESY NMR spectroscopy and distance geometry

TBA

Proximity-accelerated chemical coupling reaction in the benzodiazepine-binding site of gamma-aminobutyric acid type A receptors: superposition of different allosteric modulators.

University of Bern

Identification of anesthetic binding sites on human serum albumin using a novel etomidate photolabel.

Imperial College

Synthesis and biological evaluation of 7,8,9,10-tetrahydroimidazo[1,2-c]pyrido[3,4-e]pyrimdin-5(6H)-ones as functionally selective ligands of the benzodiazepine receptor site on the GABA(A) receptor.

Neurogen

An overview of benzo[b]thiophene-based medicinal chemistry.

Jain University

Phosphorylation of Capsaicinoid Derivatives Provides Highly Potent and Selective Inhibitors of the Transcription Factor STAT5b.

University of Leipzig

The amylase inhibitor montbretin A reveals a new glycosidase inhibition motif.

University of British Columbia

Structure-guided design of a high affinity inhibitor to human CtBP.

University of Massachusetts Medical School