The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.8M data for 1.2M Compounds and 9.2K Targets. Of those, 1,346K data for 622K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

Advanced Search

7 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Structure guided design and kinetic analysis of highly potent benzimidazole inhibitors targeting the PDEd prenyl binding site.EBI
Max Planck Institute Of Molecular Physiology
The next generation of phosphodiesterase inhibitors: structural clues to ligand and substrate selectivity of phosphodiesterases.EBI
Monash University (Parkville Campus)
Novel pyrazolopyrimidopyridazinones with potent and selective phosphodiesterase 5 (PDE5) inhibitory activity as potential agents for treatment of erectile dysfunction.EBI
Università
Quinolines as extremely potent and selective PDE5 inhibitors as potential agents for treatment of erectile dysfunction.EBI
Bristol-Myers Squibb Pharmaceutical Research Institute
Design, synthesis and biological activity of beta-carboline-based type-5 phosphodiesterase inhibitors.EBI
Pfizer
Discovery of Novel KRAS-PDE? Inhibitors by Fragment-Based Drug Design.EBI
Second Military Medical University
Structural Biology-Inspired Discovery of Novel KRAS-PDE? Inhibitors.EBI
Second Military Medical University