36 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
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Article Title
Organization
Naturally occurring polyphenolic inhibitors of amyloid beta aggregation.
Csiro Manufacturing Flagship (Biomedical)
Imidazo[2,1]thiazol-3-one Derivatives Useful as Diagnostic Agents for Alzheimer's Disease.
Temple University School Of Pharmacy
Oxidative stress in Alzheimer's disease: are we connecting the dots?
University Of Bologna
Polyfluorinated bis-styrylbenzenes as amyloid-ß plaque binding ligands.
Leiden University
Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 4. Further investigation on the inner spacer.
University Of Bologna
Aminostyrylbenzofuran derivatives as potent inhibitors for Abeta fibril formation.
Institute Of Science And Technology
Curcumin and dehydrozingerone derivatives: synthesis, radiolabeling, and evaluation for beta-amyloid plaque imaging.
Sungkyunkwan University School Of Medicine
F-18 stilbenes as PET imaging agents for detecting beta-amyloid plaques in the brain.
University Of Pennsylvania
Diphenylpropynone derivatives as probes for imagingß-amyloid plaques in Alzheimer's brains.
Kyoto University
Novel pyrrolyl 2-aminopyridines as potent and selective human beta-secretase (BACE1) inhibitors.
Wyeth
Discovery and initial optimization of 5,5'-disubstituted aminohydantoins as potent beta-secretase (BACE1) inhibitors.
Wyeth Research
(3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrrolidin-2-yl]-methanone: a potent, selective, orally active dipeptidyl peptidase IV inhibitor.
Pfizer
Small conformationally restricted piperidine N-arylsulfonamides as orally active gamma-secretase inhibitors.
Schering-Plough Research Institute
Design, synthesis, and evaluation of tetrahydroquinoline and pyrrolidine sulfonamide carbamates as gamma-secretase inhibitors.
Pharmacopeia Drug Discovery
Synthesis of biphenyltrienes as probes for beta-amyloid plaques.
University Of Pennsylvania
Novel benzofuran derivatives for PET imaging of beta-amyloid plaques in Alzheimer's disease brains.
Nagasaki University
Synthesis and evaluation of two 18F-labeled imidazo[1,2-a]pyridine analogues as potential agents for imaging beta-amyloid in Alzheimer's disease.
Emory University
Synthesis and evaluation of succinoyl-caprolactam gamma-secretase inhibitors.
Bristol-Myers Squibb Pharmaceutical Research Institute
Design, synthesis, and structure-activity relationship of novel thiophene derivatives for beta-amyloid plaque imaging.
University Of Pennsylvania
Radioiodinated flavones for in vivo imaging of beta-amyloid plaques in the brain.
Nagasaki University
Synthesis and biological activity of flurbiprofen analogues as selective inhibitors of beta-amyloid(1)(-)(42) secretion.
Chiesi Farmaceutici
Molecular-modeling based design, synthesis, and activity of substituted piperidines as gamma-secretase inhibitors.
Wyeth Research
Synthesis and evaluation of 11C-labeled 6-substituted 2-arylbenzothiazoles as amyloid imaging agents.
University Of Pittsburgh
Structure-activity relationship of imidazo[1,2-a]pyridines as ligands for detecting beta-amyloid plaques in the brain.
University Of Pennsylvania
Isomerization of (Z,Z) to (E,E)1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene in strong base: probes for amyloid plaques in the brain.
University Of Pennsylvania
Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates.
University Of Pennsylvania
Fenchylamine sulfonamide inhibitors of amyloid beta peptide production by the gamma-secretase proteolytic pathway: potential small-molecule therapeutic agents for the treatment of Alzheimer's disease.
Amgen
