BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.8M data for 1.2M Compounds and 9.2K Targets. Of those, 1,346K data for 622K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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17 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Virtual screening and optimization yield low-nanomolar inhibitors of the tautomerase activity of Plasmodium falciparum macrophage migration inhibitory factor.EBI
Yale University
An integrative in silico methodology for the identification of modulators of macrophage migration inhibitory factor (MIF) tautomerase activity.EBI
Brain Mind Institute
Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor.EBI
Yale University
Coumarin and chromen-4-one analogues as tautomerase inhibitors of macrophage migration inhibitory factor: discovery and X-ray crystallography.EBI
Yamanouchi Pharmaceutical
Synthesis and bio-evaluation of human macrophage migration inhibitory factor inhibitor to develop anti-inflammatory agent.EBI
Institute Of Chemical Biology
Benzisothiazolones as modulators of macrophage migration inhibitory factor.EBI
Yale University
Receptor agonists of macrophage migration inhibitory factor.EBI
Yale University
Optimization of N-benzyl-benzoxazol-2-ones as receptor antagonists of macrophage migration inhibitory factor (MIF).EBI
Yale University
Fragment screening of inhibitors for MIF tautomerase reveals a cryptic surface binding site.EBI
Sanofi-Aventis
Novel derivatives of ISO-1 as potent inhibitors of MIF biological function.EBI
Piramal Life Sciences
Discovery of human macrophage migration inhibitory factor (MIF)-CD74 antagonists via virtual screening.EBI
Yale University
Phenolic hydrazones are potent inhibitors of macrophage migration inhibitory factor proinflammatory activity and survival improving agents in sepsis.EBI
The New York School Of Medicine
Critical modifications of the ISO-1 scaffold improve its potent inhibition of macrophage migration inhibitory factor (MIF) tautomerase activity.EBI
Institute For Medical Research
Classification of chemical compounds by protein-compound docking for use in designing a focused library.EBI
National Institute Of Advanced Industrial Science And Technology (Aist)
Inhibition of MIF bioactivity by rational design of pharmacological inhibitors of MIF tautomerase activity.EBI
Institute For Medical Research
PXD101 analogs with L-phenylglycine-containing branched cap as histone deacetylase inhibitors.BDB
Shandong University