39 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Synthesis, structure-activity relationship of iodinated-4-aryloxymethyl-coumarins as potential anti-cancer and anti-mycobacterial agents.
P.C. Jabin Science College
Evaluation of sulfatase-directed quinone methide traps for proteomics.
Bielefeld University
Synthesis and evaluation of analogues of estrone-3-O-sulfamate as potent steroid sulfatase inhibitors.
University Of Bath
Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template.
University Of Bath
Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents.
University Of Bath
2-(1-adamantyl)-4-(thio)chromenone-6-carboxylic acids: potent reversible inhibitors of human steroid sulfatase.
Novartis Institute For Biomedical Research Vienna
Estrone formate: a novel type of irreversible inhibitor of human steroid sulfatase.
Novartis Institutes For Biomedical Research Gdc
Estrogenic potential of 2-alkyl-4-(thio)chromenone 6-O-sulfamates: potent inhibitors of human steroid sulfatase.
Novartis Research Institute Vienna
2-Substituted 4-(thio)chromenone 6-O-sulfamates: potent inhibitors of human steroid sulfatase.
Novartis Research Institute Vienna
Structure-activity relationships of 17alpha-derivatives of estradiol as inhibitors of steroid sulfatase.
Laval University
Synthesis and biological activity of the superestrogen (E)-17-oximino-3-O-sulfamoyl-1,3,5(10)-estratriene: x-ray crystal structure of (E)-17-oximino-3-hydroxy-1,3,5(10)-estratriene.
University Of Bath
Potent inhibition of steroid sulfatase activity by 3-O-sulfamate 17alpha-benzyl(or 4'-tert-butylbenzyl)estra-1,3,5(10)-trienes: combination of two substituents at positions C3 and c17alpha of estradiol.
Laval University
Active site directed inhibition of estrone sulfatase by nonsteroidal coumarin sulfamates.
University Of Bath
Estrone sulfamates: potent inhibitors of estrone sulfatase with therapeutic potential.
University Of Bath
Inhibition of estrone sulfatase (ES) by alkyl and cycloalkyl ester derivatives of 4-[(aminosulfonyl)oxy] benzoic acid.
Kingston University
2-Alkylsulfanyl estrogen derivatives: synthesis of a novel class of multi-targeted anti-tumour agents.
University Of Bath
The difluoromethylene group as a replacement for the labile oxygen in steroid sulfates: a new approach to steroid sulfatase inhibitors.
University Of Waterloo
6-(2-adamantan-2-ylidene-hydroxybenzoxazole)-O-sulfamate: a potent non-steroidal irreversible inhibitor of human steroid sulfatase.
Novartis Forschungsinstitut
The mechanism of the irreversible inhibition of estrone sulfatase (ES) through the consideration of a range of methane- and amino-sulfonate-based compounds.
Kingston University
Inhibition of estrone sulfatase (ES) by derivatives of 4-[(aminosulfonyl)oxy] benzoic acid.
Kingston University
4,4'-Benzophenone-O,O'-disulfamate: a potent inhibitor of steroid sulfatase.
Novartis Research Institute Vienna
Design, synthesis and biochemical evaluation of AC ring mimics as novel inhibitors of the enzyme estrone sulfatase (ES).
Kingston University
A novel type of nonsteroidal estrone sulfatase inhibitors.
Hans-Kn�Ll Institute Of Natural Products Research
Acid dissociation constant, a potential physicochemical factor in the inhibition of the enzyme estrone sulfatase (ES).
Kingston University
Determination and use of a transition state for the enzyme estrone sulfatase (ES) from a proposed reaction mechanism.
Kingston University
Hydrophobicity, a physicochemical factor in the inhibition of the enzyme estrone sulfatase (ES).
Kingston University
Derivation of a possible transition-state for the reaction catalysed by the enzyme estrone Sulfatase (ES).
Kingston University
17 alpha-alkyl- or 17 alpha-substituted benzyl-17 beta-estradiols: a new family of estrone-sulfatase inhibitors.
Laval University
Phosphonates and thiophosphonates as sulfate surrogates: synthesis of estrone 3-methylthiophosphonate, a potent inhibitor of estrone sulfatase
TBA
17ß-Arylsulfonamides of 17ß-aminoestra-1,3,5(10)-trien-3-ol as highly potent inhibitors of steroid sulfatase.
University Of Waterloo
Inhibition of steroid sulfatase with 4-substituted estrone and estradiol derivatives.
University Of Waterloo
Hybrid Dual Aromatase-Steroid Sulfatase Inhibitors with Exquisite Picomolar Inhibitory Activity
TBA
3,17-disubstituted 2-alkylestra-1,3,5(10)-trien-3-ol derivatives: synthesis, in vitro and in vivo anticancer activity.
University Of Bath
Thiosemicarbazones of formyl benzoic acids as novel potent inhibitors of estrone sulfatase.
Institute For Natural Products Research And Infection Biology
2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity.
University Of Bath
A-ring-substituted estrogen-3-O-sulfamates: potent multitargeted anticancer agents.
University Of Bath
N-Acyl arylsulfonamides as novel, reversible inhibitors of human steroid sulfatase.
Novartis Institutes For Biomedical Research