BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.8M data for 1.2M Compounds and 9.2K Targets. Of those, 1,346K data for 622K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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11 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Flavones: an important scaffold for medicinal chemistry.EBI
Punjabi University
(1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent¿-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction.EBI
Northwestern University
Synopsis of some recent tactical application of bioisosteres in drug design.EBI
Bristol-Myers Squibb Pharmaceutical Research And Development
Synthesis and evaluation of novel aromatic substrates and competitive inhibitors of GABA aminotransferase.EBI
Northwestern University
Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives.EBI
Huazhong University Of Science And Technology
Inactivation and inhibition of gamma-aminobutyric acid aminotransferase by conformationally restricted vigabatrin analogues.EBI
Northwestern University
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design.EBI
Bristol-Myers Squibb
4-Amino-2-(substituted methyl)-2-butenoic acids: substrates and potent inhibitors of gamma-aminobutyric acid aminotransferase.EBI
TBA
Synthesis and structure-activity relationships of a series of aminopyridazine derivatives of gamma-aminobutyric acid acting as selective GABA-A antagonists.EBI
TBA