BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.8M data for 1.2M Compounds and 9.2K Targets. Of those, 1,346K data for 622K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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16 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors.EBI
Leiden University
Discovery and characterization of an inhibitor of glucosylceramide synthase.EBI
Exelixis
Discovery of a new class of glucosylceramide synthase inhibitors.EBI
Exelixis
Dual-action lipophilic iminosugar improves glycemic control in obese rodents by reduction of visceral glycosphingolipids and buffering of carbohydrate assimilation.EBI
Leiden University
 
Synthesis and biological evaluation of four stereoisomers of PDMP-analogue, N-(2-decylamino-3-hydroxy-3-phenylprop-1-yl)-β-valienamine, and related compoundsEBI
TBA
Photoredox-based late-stage functionalization in SAR study for in vivo potent glucosylceramide synthase inhibitor.EBI
Takeda Pharmaceutical
Modified Benzofuran-carboxamide Compounds as Glucosylceramide Synthase Inhibitors for Treating Diseases.EBI
Smith, Gambrell & Russell
Discovery of Brain-Penetrant Glucosylceramide Synthase Inhibitors with a Novel Pharmacophore.EBI
Takeda Pharmaceutical
New PDMP analogues inhibit process outgrowth in an insect cell line.EBI
University of Arizona