PMID

Data

Article Title

Organization

Synthetic 1,2,3-triazole-linked glycoconjugates bind with high affinity to human galectin-3.

Fcfrp - Usp

Synthesis and evaluation of iminocoumaryl and coumaryl derivatized glycosides as galectin antagonists.

Lund University

Elements and modulation of functional dynamics.

Janssen Research And Development

Tuning the preference of thiodigalactoside- and lactosamine-based ligands to galectin-3 over galectin-1.

Utrecht University

Synthesis of bivalent lactosides and their activity as sensors for differences between lectins in inter- and intrafamily comparisons.

Ludwig-Maximilians-University Munich

1H-1,2,3-triazol-1-yl thiodigalactoside derivatives as high affinity galectin-3 inhibitors.

The Hashemite University

Galectin-inhibitory thiodigalactoside ester derivatives have antimigratory effects in cultured lung and prostate cancer cells.

Lund University

Synthesis of stable and selective inhibitors of human galectins-1 and -3.

Universit£

3-(1,2,3-Triazol-1-yl)-1-thio-galactosides as small, efficient, and hydrolytically stable inhibitors of galectin-3.

Lund University

Synthesis and galectin-binding activities of mercaptododecyl glycosides containing a terminalß-galactosyl group.

National Institute Of Advanced Industrial Science And Technology (Aist)

Protein subtype-targeting through ligand epimerization: talose-selectivity of galectin-4 and galectin-8.

Lund University

Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia.

Griffith University

Identification of Monosaccharide Derivatives as Potent, Selective, and Orally Bioavailable Inhibitors of Human and Mouse Galectin-3.

Bristol Myers Squibb

Discovery and Optimization of the First Highly Effective and Orally Available Galectin-3 Inhibitors for Treatment of Fibrotic Disease.

Galecto Biotech

Synthesis, Structure-Activity Relationships, and In Vivo Evaluation of Novel Tetrahydropyran-Based Thiodisaccharide Mimics as Galectin-3 Inhibitors.

Bristol Myers Squibb

Benzimidazole-galactosides bind selectively to the Galectin-8 N-Terminal domain: Structure-based design and optimisation.

Lund University

Structure-Guided Design of d-Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain.

Lund University

Quinoline-Pyrazole Scaffold as a Novel Ligand of Galectin-3 and Suppressor of TREM2 Signaling.

Stanford University School Of Medicine

Novel Galectin-3 Inhibitors for Treating Fibrosis.

Smith, Gambrell & Russell

A Selective Galactose-Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model.

Institute Of Science Education And Research-Kolkata (Iiser) Kolkata

Epimers Switch Galectin-9 Domain Selectivity: 3

Lund University

Binding of triazole-linked galactosyl arylsulfonamides to galectin-3 affects Trypanosoma cruzi cell invasion.

University Of Sao Paulo

Bivalent O-glycoside mimetics with S/disulfide/Se substitutions and aromatic core: Synthesis, molecular modeling and inhibitory activity on biomedically relevant lectins in assays of increasing physiological relevance.

Ludwig-Maximilians-University Munich

Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity.

Lund University

Lactosamine-Based Derivatives as Tools to Delineate the Biological Functions of Galectins: Application to Skin Tissue Repair.

Universit?? De Nantes

Arginine binding motifs: design and synthesis of galactose-derived arginine tweezers as galectin-3 inhibitors.

Lund University

Thioureido N-acetyllactosamine derivatives as potent galectin-7 and 9N inhibitors.

Lund University