31 articles for thisTarget
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In vitro and in silico PTP-1B inhibition and in vivo antidiabetic activity of semisynthetic moronic acid derivatives.
Universidad Aut£Noma Del Estado De Morelos
Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors.
Indiana University School Of Medicine
Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silico studies for PTP-1B inhibition.
Universidad Aut£Noma Del Estado De Morelos
Is RK-682 a promiscuous enzyme inhibitor? Synthesis and in vitro evaluation of protein tyrosine phosphatase inhibition of racemic RK-682 and analogues.
University Of Campinas
A potent and selective inhibitor for the UBLCP1 proteasome phosphatase.
Indiana University
Therapeutic potential of targeting the oncogenic SHP2 phosphatase.
Indiana University School Of Medicine
Synthesis, biological activity and structure-activity relationships of new benzoic acid-based protein tyrosine phosphatase inhibitors endowed with insulinomimetic effects in mouse C2C12 skeletal muscle cells.
University Of Messina
A potent and selective small-molecule inhibitor for the lymphoid-specific tyrosine phosphatase (LYP), a target associated with autoimmune diseases.
Indiana University School Of Medicine
Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold.
Indiana University School Of Medicine
Low molecular weight phosphotyrosine protein phosphatases as emerging targets for the design of novel therapeutic agents.
University Of Messina
Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells.
University Of Southern California
Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTP-1B: in vitro, in silico, and in vivo approaches.
Universidad Aut£Noma Del Estado De Morelos
New 4-[(5-arylidene-2-arylimino-4-oxo-3-thiazolidinyl)methyl]benzoic acids active as protein tyrosine phosphatase inhibitors endowed with insulinomimetic effect on mouse C2C12 skeletal muscle cells.
University Of Messina
5-Arylidene-2,4-thiazolidinediones as inhibitors of protein tyrosine phosphatases.
Universit£
Small molecule inhibitors of SHP2 tyrosine phosphatase discovered by virtual screening.
Indiana University
Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.
University Of California
Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).
Indiana University School Of Medicine
Synthesis, activity and molecular modeling of a new series of chromones as low molecular weight protein tyrosine phosphatase inhibitors.
University Of Modena And R.E.
5-Arylidene-2-phenylimino-4-thiazolidinones as PTP1B and LMW-PTP inhibitors.
University Of Messina
Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors.
Eli Lilly
Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta.
Procter & Gamble Pharmaceuticals
Discovery of Orally Bioavailable Purine-Based Inhibitors of the Low-Molecular-Weight Protein Tyrosine Phosphatase.
University Of California
Inhibition of Low Molecular Weight Protein Tyrosine Phosphatase by an Induced-Fit Mechanism.
Purdue University
SAR of non-hydrolysable analogs of pyridoxal 5'-phosphate against low molecular weight protein tyrosine phosphatase isoforms.
Saint John'S University
Allosteric Inhibitors of SHP2 with Therapeutic Potential for Cancer Treatment.
Chinese Academy Of Sciences