7 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Isoquinoline-pyridine-based protein kinase B/Akt antagonists: SAR and in vivo antitumor activity.
Abbott Laboratories
Discovery and SAR of oxindole-pyridine-based protein kinase B/Akt inhibitors for treating cancers.
Abbott Laboratories
Design and synthesis of pyridine-pyrazolopyridine-based inhibitors of protein kinase B/Akt.
Abbott Laboratories
Syntheses of potent, selective, and orally bioavailable indazole-pyridine series of protein kinase b/akt inhibitors with reduced hypotension.
Abbott Laboratories
Identification of a novel 3,5-disubstituted pyridine as a potent, selective, and orally active inhibitor of Akt1 kinase.
Abbott Laboratories
Discovery of trans-3,4'-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation.
Abbott Laboratories