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41 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of KDM5A inhibitors: Homology modeling, virtual screening and structure-activity relationship analysis.EBI
Sichuan University
Recent Progress in Histone Demethylase Inhibitors.EBI
University Of Oxford
Identification of SNAIL1 Peptide-Based Irreversible Lysine-Specific Demethylase 1-Selective Inactivators.EBI
Kyoto Prefectural University Of Medicine
Docking and Linking of Fragments To Discover Jumonji Histone Demethylase Inhibitors.EBI
University Of Oxford
Identification of Jumonji AT-Rich Interactive Domain 1A Inhibitors and Their Effect on Cancer Cells.EBI
Kyoto Prefectural University Of Medicine
Small-molecule ligands of methyl-lysine binding proteins: optimization of selectivity for L3MBTL3.EBI
University Of North Carolina At Chapel Hill
Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity.EBI
Kyoto Prefectural University Of Medicine
Recent Advances with KDM4 Inhibitors and Potential Applications.EBI
St. Jude Children'S Research Hospital
Drug discovery of histone lysine demethylases (KDMs) inhibitors (progress from 2018 to present).EBI
Hangzhou Normal University
Discovery of Novel Pyrazole-Based KDM5B Inhibitor EBI
Zhengzhou University
Discovery of a new class of JMJD6 inhibitors and structure-activity relationship study.EBI
Nankai University
Discovery of a potent and selective inhibitor of histone lysine demethylase KDM4D.EBI
Nankai University
Discovery of pyrazole derivatives as cellular active inhibitors of histone lysine specific demethylase 5B (KDM5B/JARID1B).EBI
Zhengzhou University
Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors.EBI
Genentech
Identification of potent, selective KDM5 inhibitors.EBI
Constellation Pharmaceuticals
Lead optimization of a pyrazolo[1,5-a]pyrimidin-7(4H)-one scaffold to identify potent, selective and orally bioavailable KDM5 inhibitors suitable for in vivo biological studies.EBI
Genentech
Identification of novel lysine demethylase 5-selective inhibitors by inhibitor-based fragment merging strategy.EBI
Kyoto Prefectural University Of Medicine
Identification of ortho-hydroxy anilide as a novel scaffold for lysine demethylase 5 inhibitors.EBI
Kyoto Prefectural University Of Medicine
Optimisation of a triazolopyridine based histone demethylase inhibitor yields a potent and selective KDM2A (FBXL11) inhibitor.EBI
University Of Oxford
The structure-activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface.EBI
University Of North Carolina
Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A.EBI
The University Of Texas M.D. Anderson Cancer Center
Structure-based design and discovery of potent and selective KDM5 inhibitors.EBI
Celgene
Methyllysine binding domains: Structural insight and small molecule probe development.EBI
University Of Connecticut
Investigations on small molecule inhibitors targeting the histone H3K4 tri-methyllysine binding PHD-finger of JmjC histone demethylases.EBI
University Of Oxford
From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors.EBI
Genentech
Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A.EBI
The University Of Texas M.D. Anderson Cancer Center
Discovery of pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives as a new class of histone lysine demethylase 4D (KDM4D) inhibitors.EBI
Sichuan University
Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.BDB
University Of Oxford
An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells.BDB
Genentech
Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1.BDB
University Of North Carolina At Chapel Hill
Identification and Characterization of Small Molecule Inhibitors of a Plant Homeodomain Finger.BDB
University Of Wisconsin