BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.8M data for 1.2M Compounds and 9.2K Targets. Of those, 1,346K data for 622K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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6 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of a Potent and Selective ROMK Inhibitor with Pharmacokinetic Properties Suitable for Preclinical Evaluation.EBI
Merck Research Laboratories
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.EBI
University Of Oxford
Discovery of (R)-(3-fluoropyrrolidin-1-yl)(6-((5-(trifluoromethyl)pyridin-2-yl)oxy)quinolin-2-yl)methanone (ABBV-318) and analogs as small molecule NaEBI
Abbvie
Discovery of Selective Inhibitors of NaEBI
Siteone Therapeutics
Discovery of Acyl-sulfonamide NaEBI
Genentech
Challenges and Opportunities for Therapeutics Targeting the Voltage-Gated Sodium Channel Isoform NaEBI
Siteone Therapeutics