BindingDB logo
myBDB logout

20 articles for Actelion Pharmaceuticals Ltd

The following articles (labelled with PubMed ID or TBD) are for your review
PMIDArticle TitlePublishedDeposition
26231163 Discovery of novel bridged tetrahydronaphthalene derivatives as potent T/L-type calcium channel blockers. 17-8 -2015 27-NOV-2016
26045032 Recent trends in orexin research--2010 to 2015. 13-6 -2015 14-NOV-2016
25838147 Substituted pyrrolidin-2-ones: Centrally acting orexin receptor antagonists promoting sleep. Part 2. 23-APR-2015 23-APR-2016
25113932 Optimization of 2-phenyl-pyrimidine-4-carboxamides towards potent, orally bioavailable and selective P2Y(12) antagonists for inhibition of platelet aggregation. 26-AUG-2014 01-APR-2016
US9096595 7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido[1,2-a]indol acetic acid derivatives and their use as prostaglandin D2 receptor modulators 04-AUG-2015 28-MAR-2016
24447850 Discovery of substituted lactams as novel dual orexin receptor antagonists. Synthesis, preliminary structure-activity relationship studies and efforts towards improved metabolic stability and pharmacokinetic properties. Part 1. 10-FEB-2014 25-JUL-2014
23719231 Structure-activity relationship studies and sleep-promoting activity of novel 1-chloro-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine derivatives as dual orexin receptor antagonists. Part 2. 10-JUN-2013 13-APR-2014
23968485 Design, synthesis, and characterization of novel tetrahydropyran-based bacterial topoisomerase inhibitors with potent anti-gram-positive activity. 26-SEP-2013 13-APR-2014
23324405 Evolution of novel tricyclic CRTh2 receptor antagonists from a (E)-2-cyano-3-(1H-indol-3-yl)acrylamide scaffold. 28-JAN-2013 13-APR-2014
23434414 Synthesis, structure-activity relationship studies, and identification of novel 5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine derivatives as dual orexin receptor antagonists. Part 1. 18-MAR-2013 24-SEP-2013
23006603 Structure-guided design, synthesis and biological evaluation of novel DNA ligase inhibitors with in vitro and in vivo anti-staphylococcal activity. 15-OCT-2012 17-MAY-2013
22726929 Novel 2-(2-(benzylthio)-1H-benzo[d]imidazol-1-yl)acetic acids: discovery and hit-to-lead evolution of a selective CRTh2 receptor antagonist chemotype. 03-JUL-2012 08-FEB-2013
20843686 Design and optimization of new piperidines as renin inhibitors. 11-OCT-2010 13-JUN-2011
20843690 Piperidine-based renin inhibitors: upper chain optimization. 11-OCT-2010 13-JUN-2011
20144866 Novel pyrazolo-tetrahydropyridines as potent orexin receptor antagonists. 22-FEB-2010 18-NOV-2010
19853442 New classes of potent and bioavailable human renin inhibitors. 05-NOV-2009 17-NOV-2010
18845436 N-Glycine-sulfonamides as potent dual orexin 1/orexin 2 receptor antagonists. 30-OCT-2009 25-AUG-2010
12617929 The use of sulfonylamido pyrimidines incorporating an unsaturated side chain as endothelin receptor antagonists. 05-MAR-2003 10-NOV-2009
17000102 Inhibitors of Plasmepsin II-potential antimalarial agents. 19-NOV-2006 10-NOV-2009
12617928 Bis-sulfonamides as endothelin receptor antagonists. 05-MAR-2003 10-NOV-2009