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26 articles for Adolor Corporation


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDArticle TitlePublishedDeposition
US8580788 Opioid antagonists 12-NOV-2013 06-MAR-2014
19464172 Nascent structure-activity relationship study of a diastereomeric series of kappa opioid receptor antagonists derived from CJ-15,208. 09-JUN-2009 22-DEC-2012
18788723 Potent, orally bioavailable delta opioid receptor agonists for the treatment of pain: discovery of N,N-diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide (ADL5859). 02-OCT-2008 19-DEC-2012
18430570 Sulfamoyl benzamides as novel CB2 cannabinoid receptor ligands. 05-MAY-2008 16-DEC-2012
18487043 Use of receptor chimeras to identify small molecules with high affinity for the dynorphin A binding domain of the kappa opioid receptor. 10-JUN-2008 15-DEC-2012
18024030 Discovery of a series of aminopiperidines as novel iNOS inhibitors. 09-JAN-2008 15-DEC-2012
17149859 Synthesis and pharmacological evaluation of novel octahydro-1H-pyrido[1,2-a]pyrazine as mu-opioid receptor antagonists. 07-DEC-2006 09-DEC-2012
17149858 Elucidation of the bioactive conformation of the N-substituted trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine class of mu-opioid receptor antagonists. 07-DEC-2006 09-DEC-2012
14643346 trans-3,4-dimethyl-4-(3-carboxamidophenyl)piperidines: a novel class of micro-selective opioid antagonists. 03-DEC-2003 09-OCT-2012
18313920 Novel trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines as mu opioid receptor antagonists with improved opioid receptor selectivity profiles. 15-XXX-2008 12-JUN-2012
19919895 Novel sulfamoyl benzamides as selective CB(2) agonists with improved in vitro metabolic stability. 03-FEB-2010 31-AUG-2010
19646869 Discovery of N-(3-(morpholinomethyl)-phenyl)-amides as potent and selective CB2 agonists. 17-AUG-2009 30-AUG-2010
19736007 Novel pyridine derivatives as potent and selective CB2 cannabinoid receptor agonists. 28-SEP-2009 30-AUG-2010
19694468 Spirocyclic delta opioid receptor agonists for the treatment of pain: discovery of N,N-diethyl-3-hydroxy-4-(spiro[chromene-2,4'-piperidine]-4-yl) benzamide (ADL5747). 17-SEP-2009 27-AUG-2010
19091565 CB2 selective sulfamoyl benzamides: optimization of the amide functionality. 26-DEC-2008 11-JAN-2010
17307360 Novel malonamide derivatives as potent kappa opioid receptor agonists. 13-MAR-2007 10-NOV-2009
17507224 Biaryl cannabinoid mimetics--synthesis and structure-activity relationship. 18-JUN-2007 10-NOV-2009
11086731 Arylacetamides as peripherally restricted kappa opioid receptor agonists. 12-FEB-2001 10-NOV-2009
15686919 Synthesis and evaluation of novel peripherally restricted kappa-opioid receptor agonists. 02-FEB-2005 10-NOV-2009
16203140 Potent and highly selective kappa opioid receptor agonists incorporating chroman- and 2,3-dihydrobenzofuran-based constraints. 19-OCT-2005 10-NOV-2009
15863335 Arylacetamide kappa opioid receptor agonists with reduced cytochrome P450 2D6 inhibitory activity. 02-MAY-2005 10-NOV-2009
15482950 Azepinone as a conformational constraint in the design of kappa-opioid receptor agonists. 14-OCT-2004 10-NOV-2009
16263278 Novel phenylamino acetamide derivatives as potent and selective kappa opioid receptor agonists. 26-DEC-2005 10-NOV-2009
16298525 Synthesis and structure-activity relationships of a new series of 2alpha-substituted trans-4,5-dimethyl-4-(3-hydroxyphenyl)piperidine as mu-selective opioid antagonists. 09-JAN-2006 10-NOV-2009
15713370 Amino acid conjugates as kappa opioid receptor agonists. 16-FEB-2005 10-NOV-2009
17350835 Further studies of tyrosine surrogates in opioid receptor peptide ligands. 06-APR-2007 10-NOV-2009