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9 articles for Amgen Inc

The following articles (labelled with PubMed ID or TBD) are for your review
PMIDArticle TitlePublishedDeposition
26812066 Discovery of (R)-6-(1-(8-Fluoro-6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one (AMG 337), a Potent and Selective Inhibitor of MET with High Unbound Target Coverage and Robust In Vivo Antitumor Activity. 24-MAR-2016 13-JUL-2017
22926069 Phenylalanine derivatives as GPR142 agonists for the treatment of type II diabetes. 17-SEP-2012 17-MAY-2013
21376583 Discovery of triazine-benzimidazoles as selective inhibitors of mTOR. 14-MAR-2011 03-DEC-2011
21093258 Synthesis and optimization of novel 4,4-disubstituted cyclohexylbenzamide derivatives as potent 11ß-HSD1 inhibitors. 24-DEC-2010 22-AUG-2011
19864130 Design and synthesis of 6-oxo-1,6-dihydropyridines as CDK5 inhibitors. 05-NOV-2009 29-AUG-2010
19574047 Part 1: Structure-Activity Relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38alpha mitogen-activated protein kinase. 29-JUL-2009 27-AUG-2010
18652443 Blockade of glucocorticoid excess at the tissue level: inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 as a therapy for type 2 diabetes. 22-AUG-2008 11-JAN-2010
19062274 Discovery of alpha-amidosulfones as potent and selective agonists of CB2: synthesis, SAR, and pharmacokinetic properties. 26-DEC-2008 11-JAN-2010
18447379 Discovery of aryl aminoquinazoline pyridones as potent, selective, and orally efficacious inhibitors of receptor tyrosine kinase c-Kit. 05-JUN-2008 11-JAN-2010