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9 articles for Astex Pharmaceuticals


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDArticle TitlePublishedDeposition
27933945 Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA 08-DEC-2016 16-JUL-2018
27739691 Fragment-to-Lead Medicinal Chemistry Publications in 2015. 12-JAN-2017 15-JUL-2018
27167608 Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening. 10-JUN-2016 26-SEP-2017
27031670 Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery. 28-APR-2016 22-SEP-2017
26191369 Fragment-Based Discovery of Potent and Selective DDR1/2 Inhibitors. 20-7 -2015 19-NOV-2016
26218264 Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Discovery of a Non-Alanine Lead Series with Dual Activity Against cIAP1 and XIAP. 28-8 -2015 15-NOV-2016
25589925 Fragment-based discovery of type I inhibitors of maternal embryonic leucine zipper kinase. 15-JAN-2015 19-MAR-2016
25589926 Structure-Based Design of Type II Inhibitors Applied to Maternal Embryonic Leucine Zipper Kinase. 15-JAN-2015 19-MAR-2016
23023261 Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function. XX-NOV-2012 28-DEC-2012