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14 articles for Aventis Pharma

The following articles (labelled with PubMed ID or TBD) are for your review
PMIDArticle TitlePublishedDeposition
11266171 RPR203494 a pyrimidine analogue of the p38 inhibitor RPR200765A with an improved in vitro potency. 12-MAR-2001 30-OCT-2018
11378377 Fine Tuning of physico-chemical parameters to optimise a new series of novobiocin analogues. 04-JUN-2001 26-OCT-2018
12086479 Principles governing the binding of a class of non-peptidic inhibitors to the SH2 domain of src studied by X-ray analysis. 27-JUN-2002 26-NOV-2012
12527336 Affinity of cyamemazine, an anxiolytic antipsychotic drug, for human recombinant dopamine vs. serotonin receptor subtypes. 01-XXX-2003 13-MAY-2012
12086480 Structural requirements for inhibition of the neuronal nitric oxide synthase (NOS-I): 3D-QSAR analysis of 4-oxo- and 4-amino-pteridine-based inhibitors. 27-JUN-2002 10-NOV-2009
11206465 Solid-phase optimisation of achiral amidinobenzyl indoles as potent and selective factor Xa inhibitors. 05-FEB-2001 10-NOV-2009
11229763 Synthesis of analogues of the O-beta-D-ribofuranosyl nucleoside moiety of liposidomycins. Part 1: contribution of the amino group and the uracil moiety upon the inhibition of MraY. 02-MAR-2001 10-NOV-2009
11965374 Small ligands interacting with the phosphotyrosine binding pocket of the Src SH2 protein. 19-APR-2002 10-NOV-2009
11965373 Discovery of highly potent Src SH2 binders: structure-activity studies and X-ray structures. 19-APR-2002 10-NOV-2009
11965372 Imidazole-based ligands of the Src SH2 protein. 19-APR-2002 10-NOV-2009
14613321 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. 20-NOV-2003 02-APR-2007
10966741 Crystal structures of human factor Xa complexed with potent inhibitors. 24-AUG-2000 06-MAR-2007
12593649 Molecular structures of human factor Xa complexed with ketopiperazine inhibitors: preference for a neutral group in the S1 pocket. 27-FEB-2003 19-DEC-2006
15999990 Probing the subpockets of factor Xa reveals two binding modes for inhibitors based on a 2-carboxyindole scaffold: a study combining structure-activity relationship and X-ray crystallography. 14-JUL-2005 11-DEC-2006